| Tag | Content |
|---|---|
| Uniprot ID | D3ZJ19 |
| Entrez ID | 501145 |
| Genbank protein ID | EDL99029.1 |
| Genbank nucleotide ID | NM_001109306.1 |
| Ensembl protein ID | ENSRNOP00000071049; ENSRNOP00000044829; |
| Ensembl nucleotide ID | ENSRNOG00000010188 |
| Gene name | DNA-binding protein SATB |
| Gene symbol | Satb2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MERRSESPCL RDSPDRRSGS PDVKGPPPVK VARLEQNGSP MGARGRPNGA VAKAVGGLMI 60 PVFCVVEQLD GSLEYDNREE HAEFVLVRKD VLFSQLVETA LLALGYSHSS AAQAQGIIKL 120 GRWNPLPLSY VTDAPDATVA DMLQDVYHVV TLKIQLQSCS KLEDLPAEQW NHATVRNALK 180 ELLKEMNQST LAKECPLSQS MISSIVNSTY YANVSATKCQ EFGRWYKKYK KIKVERVERE 240 NLSDYCVLGQ RPMHLPNMNQ LASLGKTNEQ SPHSQIHHST PIRNQVPALQ PIMSPGLLSP 300 QLSPQLVRQQ IAMAHLINQQ IAVSRLLAHQ HPQAINQQFL NHPPIPRAVK PEPTNSSVEV 360 SPDIYQQVRD ELKRASVSQA VFARVAFNRT QGLLSEILRK EEDPRTASQS LLVNLRAMQN 420 FLNLPEVERD RIYQDERERS MNPNVSMVSS ASSSPSSSRT PQAKTSTPTT DLPIKVDGAN 480 VNITAAIYDE IQQEMKRAKV SQALFAKVAA NKSQGWLCEL LRWKENPSPE NRTLWENLCT 540 IRRFLNLPQH ERDVIYEEES RHHHSERMQH VVQLPPEPVQ VLHRQQSQPT KESSPPREEA 600 PPPPPPTEDS CAKKPRSRTK ISLEALGILQ SFIHDVGLYP DQEAIHTLSA QLDLPKHTII 660 KFFQNQRYHV KHHGKLKEHL GSAVDVAEYK DEELLTESEE NDSEEGSDEM YKVEAEEESA 720 EKNKVAPAET DQR 733 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | SATB2 | 102171018 | A0A452FN88 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | SATB2 | 23314 | Q9UPW6 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Satb2 | 212712 | Q8VI24 | CPO | E12.5, E14.25, E13.5, E14.5, E16.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | SATB2 | 459856 | A0A2I3SX19 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | SATB2 | I3LRU7 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | SATB2 | 100351405 | G1SXR2 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Satb2 | 501145 | D3ZJ19 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | satb2 | 563435 | A8WIP9 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0000118 | histone deacetylase complex |
| GO:0005634 | nucleus |
| GO:0005667 | transcription factor complex |
| GO:0003682 | chromatin binding |
| GO:0001228 | DNA-binding transcription activator activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0043565 | sequence-specific DNA binding |
| GO:0051216 | cartilage development |
| GO:0071310 | cellular response to organic substance |
| GO:0006338 | chromatin remodeling |
| GO:0021902 | commitment of neuronal cell to specific neuron type in forebrain |
| GO:0009880 | embryonic pattern specification |
| GO:0048704 | embryonic skeletal system morphogenesis |
| GO:0000122 | negative regulation of transcription by RNA polymerase II |
| GO:0001764 | neuron migration |
| GO:0002076 | osteoblast development |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |
| GO:0010468 | regulation of gene expression |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060021 | roof of mouth development |