Gene: Pcgf2

Basic information

Tag Content
Uniprot ID B2RZ82
Entrez ID 287662
Genbank protein ID EDM05871.1; AAI67059.1; EDM05872.1; EDM05873.1; EDM05870.1;
Genbank nucleotide ID XM_008767971.1; NM_001105836.2; XM_008767972.1; XM_008767973.2;
Ensembl protein ID ENSRNOP00000017241
Ensembl nucleotide ID ENSRNOG00000012705
Gene name Pcgf2 protein
Gene symbol Pcgf2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MHRTTRIKIT ELNPHLMCAL CGGYFIDATT IVECLHSFCK TCIVRYLETN KYCPMCDVQV 60
HKTRPLLSIR SDKTLQDIVY KLVPGLFKDE MKRRRDFYAA YPLTEVPNGS NEDRGEVLEQ 120
EKGALGDDEI VSLSIEFYEG VRDREEKKSL VENGDGDKEK TGVRFLRCPA AMTVMHLAKF 180
LRNKMDVPSK YKVEILYEDE PLKEYYTLMD IAYIYPWRRN GPLPLKYRVQ PACKRLTLPT 240
VPTPSEGTNT SGASECESVS DKAPSPATLP ATSSSLPSPA TPSHGSPSSH GPPATHPTSP 300
TPPSTAAGTT TATNGGTSNC LQTPSSTSRG RKMTVNGAPC PP 342

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPCGF2505147E1BMR4Bos taurusPredictionMore>>
1:1 orthologPCGF2102174970A0A452F706Capra hircusPredictionMore>>
1:1 orthologPCGF27703P35227Homo sapiensPredictionMore>>
1:1 orthologPcgf222658P23798CPOMus musculusPublicationMore>>
1:1 orthologPCGF2454614H2QCT2Pan troglodytesPredictionMore>>
1:1 orthologPCGF2A0A287A7A5Sus scrofaPredictionMore>>
1:1 orthologPcgf2287662B2RZ82Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0016604 nuclear body
GO:0000790 nuclear chromatin
GO:0005634 nucleus
GO:0031519 PcG protein complex
GO:0035102 PRC1 complex
GO:0001739 sex chromatin
GO:0003682 chromatin binding
GO:1990841 promoter-specific chromatin binding
GO:0009952 anterior/posterior pattern specification
GO:0070301 cellular response to hydrogen peroxide
GO:0006342 chromatin silencing
GO:0048706 embryonic skeletal system development
GO:0048704 embryonic skeletal system morphogenesis
GO:0016573 histone acetylation
GO:0036353 histone H2A-K119 monoubiquitination
GO:0001701 in utero embryonic development
GO:2001234 negative regulation of apoptotic signaling pathway
GO:0000122 negative regulation of transcription by RNA polymerase II
GO:0050790 regulation of catalytic activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR032443 RAWUL
IPR001841 Znf_RING
IPR013083 Znf_RING/FYVE/PHD
IPR017907 Znf_RING_CS

PROSITE

PROSITE ID PROSITE Term
PS00518 ZF_RING_1
PS50089 ZF_RING_2

Pfam

Pfam ID Pfam Term
PF16207 RAWUL