Gene: Nectin3

Basic information

Tag Content
Uniprot ID D4A5C0
Entrez ID 288124
Genbank protein ID EDM11121.1
Genbank nucleotide ID NM_001105883.1
Ensembl protein ID ENSRNOP00000002957
Ensembl nucleotide ID ENSRNOG00000002176
Gene name Nectin cell adhesion molecule 3
Gene symbol Nectin3
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MARTPGPALL CPGGGKAQLS SASPPAAGLL LPAPTPPPLL LLLIPLLLFS RLCGALAGSI 60
IVEPHVTAVW GKNVSLKCLI EVNETITQIS WEKIHGKSTQ TVAVHHPQYG FSVQGEYQGR 120
ILFKNYSLND ATITLHNIGF SDSGKYICKA VTFPLGNAQS STTVTVLVEP TVSLMKGPDS 180
LIDGGNETVA AVCIAATGKP VARIDWEGDL GEMESTITSF PNETATIISQ YKLFPTRFAR 240
GRRITCVVKH PALEKDIRYS FILDIQYAPE VSVTGYDGNW FVGRKGVNLK CNADANPPPF 300
KSVWSRLDGE WPDGLLASDN TLHFVHPLTF NYSGVYVCKV TNSLGQRSDQ KVIYISDIPL 360
KQTSSIAVAG AVIGAVLALF IIAVFVTVLL TPRKKRPSYL DKVIDLPPTH KPPPVYEERI 420
PSLPQKNRLF QTERLPLQTQ FKEKGAGGLQ PPNGPIRRLD YEDENTVQED GTQQMCPLYN 480
QMCHQDRSPH QHRPRNPERL YINPREHYV 509

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNECTIN325945Q9NQS3Homo sapiensPublicationMore>>
1:1 orthologNectin358998Q9JLB9Mus musculusPredictionMore>>
1:1 orthologNECTIN3742869H2QN30Pan troglodytesPredictionMore>>
1:1 orthologNectin3288124D4A5C0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005912 adherens junction
GO:0043296 apical junction complex
GO:0030424 axon
GO:0044291 cell-cell contact zone
GO:0005911 cell-cell junction
GO:0030425 dendrite
GO:0098686 hippocampal mossy fiber to CA3 synapse
GO:0099061 integral component of postsynaptic density membrane
GO:0005886 plasma membrane
GO:0045202 synapse
GO:0050839 cell adhesion molecule binding
GO:0042802 identical protein binding
GO:0042803 protein homodimerization activity
GO:0038023 signaling receptor activity
GO:0007155 cell adhesion
GO:0098609 cell-cell adhesion
GO:0061951 establishment of protein localization to plasma membrane
GO:0009566 fertilization
GO:0007157 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules
GO:0007156 homophilic cell adhesion via plasma membrane adhesion molecules
GO:0002089 lens morphogenesis in camera-type eye
GO:1902414 protein localization to cell junction
GO:0060042 retina morphogenesis in camera-type eye
GO:0007286 spermatid development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0393 Immunoglobulin domain
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR033319 Nectin-3

PROSITE

PROSITE ID PROSITE Term
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF08205 C2-set_2
PF07686 V-set