Gene: NECTIN3

Basic information

Tag Content
Uniprot ID H2QN30
Entrez ID 742869
Genbank protein ID
Genbank nucleotide ID XM_016941623.1
Ensembl protein ID ENSPTRP00000026234
Ensembl nucleotide ID ENSPTRG00000015204
Gene name Nectin cell adhesion molecule 3
Gene symbol NECTIN3
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAEGWRWCFV RRTPGLLRGP LLPRSFPGNR RALAGPIIVE PHVTAVWGKN VSLKCLIEVN 60
ETITQISWEK IHGKSSQTVA VHHPQYGFSV QGEYQGRVLF KNYSLNDATI TLHNIGFSDS 120
GKYICKAVTF PLGNAQSSTT VTVLVEPTVS LIKGPDSLID GGNETVAAIC IAATGKPVAH 180
IDWEGDLGEM ESTTTSFPNE TATIISQYKL FPTRFARGRR ITCVVKHPAL EKDIRYSFIL 240
DIQYAPEVSV TGYDGNWFVG RKGVNLKCNA DANPPPFKSV WSRLDGQWPD GLLASDNTLH 300
FVHPLTFNYS GVYICKVTNS LGQRSDQKVI YISDVPFKQT SSIAVAGAVI GAVLALFIIA 360
IFVTVLLTPR KKRPSYLDKV IDLPPTHKPP PVYEERSPPL PQKDLFQPEH LPLQTQFKER 420
EVGNLQHSNG LNSRSFDYED ENPVGEDGIQ QMYPLYNQMC YQDRSPGKHH QNNDPKRVYI 480
DPREHYV 487

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologNECTIN325945Q9NQS3Homo sapiensPublicationMore>>
1:1 orthologNectin358998Q9JLB9Mus musculusPredictionMore>>
1:1 orthologNECTIN3742869H2QN30Pan troglodytesPredictionMore>>
1:1 orthologNectin3288124D4A5C0Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005911 cell-cell junction
GO:0016021 integral component of membrane
GO:0050839 cell adhesion molecule binding
GO:0042803 protein homodimerization activity
GO:0007155 cell adhesion
GO:0007286 spermatid development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1015 Disulfide bond
KW-0393 Immunoglobulin domain
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR013162 CD80_C2-set
IPR007110 Ig-like_dom
IPR036179 Ig-like_dom_sf
IPR013783 Ig-like_fold
IPR003599 Ig_sub
IPR013106 Ig_V-set
IPR033319 Nectin-3

PROSITE

PROSITE ID PROSITE Term
PS50835 IG_LIKE

Pfam

Pfam ID Pfam Term
PF08205 C2-set_2
PF07686 V-set