| Tag | Content |
|---|---|
| Uniprot ID | E1BBM6 |
| Entrez ID | 539808 |
| Genbank protein ID | |
| Genbank nucleotide ID | NM_001192313.1 |
| Ensembl protein ID | ENSBTAP00000014023 |
| Ensembl nucleotide ID | ENSBTAG00000010605 |
| Gene name | Ventral anterior homeobox 2 |
| Gene symbol | VAX2 |
| Organism | Bos taurus |
| NCBI taxa ID | 9913 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGDGGTERDR GPARRESQSG RGGDGGGAED STADAGGRSP REIAGTSDSS PAGSRESGAD 60 RDGQPGLGEA DHCRRILVRD AKGTIREIVL PKGLDLDRPK RTRTSFTAEQ LYRLEMEFQR 120 CQYVVGRERT ELARQLNLSE TQVKVWFQNR RTKQKKDQSR DLEKRASSSA SKAFATSNIL 180 RLLEHGRLLS VPRAPSLLAL TPGPPGLPAG HRGTSLGDPR NSSPHLNPLT SASPPLPPPP 240 PALCFSTAPL LDLPAGYELG SSAFEPYSRL DRRVGSPGGS SKKASA 286 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VAX2 | 539808 | E1BBM6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | VAX2 | 102188324 | A0A452E6B0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | VAX2 | 25806 | Q9UIW0 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Vax2 | 24113 | Q9WTP9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | VAX2 | A0A2I3SNN0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | VAX2 | F1SLE1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Vax2 | G3V7R0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | vax2 | 373869 | Q801E1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0031490 | chromatin DNA binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0000978 | RNA polymerase II cis-regulatory region sequence-specific DNA binding |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding |
| GO:0007409 | axonogenesis |
| GO:0007417 | central nervous system development |
| GO:0009950 | dorsal/ventral axis specification |
| GO:0048048 | embryonic eye morphogenesis |
| GO:0030900 | forebrain development |
| GO:0030182 | neuron differentiation |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0060041 | retina development in camera-type eye |
| GO:0007601 | visual perception |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |