| Tag | Content |
|---|---|
| Uniprot ID | G3V7R0 |
| Entrez ID | |
| Genbank protein ID | EDL91158.1 |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSRNOP00000018128 |
| Ensembl nucleotide ID | ENSRNOG00000013261 |
| Gene name | Ventral anterior homeobox 2 |
| Gene symbol | Vax2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGDGGAERDR GPKRREEPGG RSGCRGEHRG AEDLRADTGS TSPREIAGTS ASSPAGSRES 60 GGDSDGQQAL GETDHCRRIL VRDAKGTIRE IVLPKGLDLD RPKRTRTSFT AEQLYRLEME 120 FQRCQYVVGR ERTELARQLN LSETQVKVWF QNRRTKQKKD QSRDLEKRAS SSASEAFATS 180 NVLRLLEQGR LLSVPRAPSL LALSPGLPGL TAGHRGTSLG DPRNSSQRLN PMPSASASSP 240 LPPPLPAVCF SAAPLLDLPA SYKLGSSAFE PYSRLEQQKV GSPGQSDKKA DI 292 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | VAX2 | 539808 | E1BBM6 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | VAX2 | 102188324 | A0A452E6B0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | VAX2 | 25806 | Q9UIW0 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Vax2 | 24113 | Q9WTP9 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | VAX2 | A0A2I3SNN0 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | VAX2 | F1SLE1 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Vax2 | G3V7R0 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | vax2 | 373869 | Q801E1 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005634 | nucleus |
| GO:0031490 | chromatin DNA binding |
| GO:0001227 | DNA-binding transcription repressor activity, RNA polymerase II-specific |
| GO:0001162 | RNA polymerase II intronic transcription regulatory region sequence-specific DNA binding |
| GO:0007409 | axonogenesis |
| GO:0009950 | dorsal/ventral axis specification |
| GO:0048048 | embryonic eye morphogenesis |
| GO:0030900 | forebrain development |
| GO:0060041 | retina development in camera-type eye |
| GO:0007601 | visual perception |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |