Gene: CRISPLD2

Basic information

Tag Content
Uniprot ID E2QU10
Entrez ID 489677
Genbank protein ID
Genbank nucleotide ID XM_546797.5
Ensembl protein ID ENSCAFP00000029542
Ensembl nucleotide ID ENSCAFG00000019943
Gene name Cysteine rich secretory protein LCCL domain containing 2
Gene symbol CRISPLD2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSLNGVVPLG LVLLVCGAQG FFLPNVTHLE KLLSKYQQDK PHSRVRRAIP RSDKEEILML 60
HNKLRGQVYP PASNMEYMTW DEELEQSAAA WAQECIWEHG PTGLLVSIGQ NLAVHWGRYR 120
SPGFHVQSWY DEVKDYTYPY PHECNPWCPE RCSGPMCTHY TQIVWATTNK IGCAVNTCRR 180
MNVWGDVWEN AVYLVCNYSP KGNWIGEAPY KTGRPCSECP PSYGGSCNNN LCYRGESYSP 240
KPETDEMNEV EVAPIPEEKH VWVQPRVVRP TKPKKAPAVN YMTQVVRCDT KMKDKCKGST 300
CNRYQCPAGC LESKAKVFGT LFYESSSSIC RAAIHYGILD SKGGLVDVTR NGKVPFFVRS 360
ERHGVESLSK YKPSSSFVVS KVKVQDLDCY TTVAQLCPFE KAGTHCPRVH CPAHCKDEPS 420
YWAPVFGTNI YADSSSICKT AVHAGVIRNE SGGYVDVMPV DKKKTYVGSL RNGIQSESLR 480
TPRDGKAFRI FAVRQ 495

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCRISPLD2505329A6QLZ7Bos taurusPredictionMore>>
1:1 orthologCRISPLD2489677E2QU10Canis lupus familiarisPredictionMore>>
1:1 orthologCRISPLD2102186984A0A452FWH8Capra hircusPredictionMore>>
1:1 orthologCRISPLD2100070252A0A3Q2GZC0Equus caballusPredictionMore>>
1:1 orthologCRISPLD283716Q9H0B8CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologCrispld278892Q8BZQ2Mus musculusPredictionMore>>
1:1 orthologCRISPLD2454288K7A8K8Pan troglodytesPredictionMore>>
1:1 orthologCRISPLD2K7GSW9Sus scrofaPredictionMore>>
1:1 orthologCrispld2171547G3V9T1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0031012 extracellular matrix
GO:0005615 extracellular space
GO:0030133 transport vesicle
GO:0005539 glycosaminoglycan binding
GO:0008201 heparin binding
GO:0030198 extracellular matrix organization
GO:0060325 face morphogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR018244 Allrgn_V5/Tpx1_CS
IPR014044 CAP_domain
IPR035940 CAP_sf
IPR001283 CRISP-related
IPR004043 LCCL
IPR036609 LCCL_sf

PROSITE

PROSITE ID PROSITE Term
PS01010 CRISP_2
PS50820 LCCL

Pfam

Pfam ID Pfam Term
PF00188 CAP
PF03815 LCCL