Gene: CRISPLD2

Basic information

Tag Content
Uniprot ID K7A8K8; H2R269;
Entrez ID 454288
Genbank protein ID JAA04212.1; JAA14096.1; JAA22712.1;
Genbank nucleotide ID XM_016930296.1
Ensembl protein ID ENSPTRP00000043479
Ensembl nucleotide ID ENSPTRG00000008422
Gene name Cysteine-rich secretory protein LCCL domain-containing 2
Gene symbol CRISPLD2
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MSCVLGGVIP LGLLFLVCGS QGYLLPNVTL LEELLSKYQH NESHSRVRRA IPREDKEEIL 60
MLHNKLRGQV QPQASNMEYM TWDDELEKSA AAWASQCIWE HGPTSLLVSI GQNLGAHWGR 120
YRSPGFHVQS WYDEVKDYTY PYPSECNPWC PERCSGPMCT HYTQIVWATT NKIGCAVNTC 180
RKMTVWGEVW ENAVYFVCNY SPKGNWIGEA PYKNGRPCSE CPPSYGGSCR NNLCYREETY 240
TPKPETDEMN EVETAPIPEE NHVWLQPRVM RPTKPKKTSA VNYMTQVVRC DTKMKDRCKG 300
STCNRYQCPA GCLNHKAKIF GTLFYESSSS ICRAAIHYGI LDDKGGLVDI TRNGKVPFFV 360
KSERHGVQSL SKYKPSSSFM VSKVKVQDLD CYTTVAQLCP FEKPATHCPR IHCPAHCKDE 420
PSYWAPVFGT NIYADTSSIC KTAVHAGVIS NESGGDVDVM PVDKKKTYVG SLRNGVQSES 480
LGTPRDGKAF RIFAVRQ 497

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologCRISPLD2505329A6QLZ7Bos taurusPredictionMore>>
1:1 orthologCRISPLD2489677E2QU10Canis lupus familiarisPredictionMore>>
1:1 orthologCRISPLD2102186984A0A452FWH8Capra hircusPredictionMore>>
1:1 orthologCRISPLD2100070252A0A3Q2GZC0Equus caballusPredictionMore>>
1:1 orthologCRISPLD283716Q9H0B8CPO,CL/PHomo sapiensPublicationMore>>
1:1 orthologCrispld278892Q8BZQ2Mus musculusPredictionMore>>
1:1 orthologCRISPLD2454288K7A8K8Pan troglodytesPredictionMore>>
1:1 orthologCRISPLD2K7GSW9Sus scrofaPredictionMore>>
1:1 orthologCrispld2171547G3V9T1Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0031012 extracellular matrix
GO:0005615 extracellular space
GO:0030133 transport vesicle
GO:0005539 glycosaminoglycan binding
GO:0008201 heparin binding
GO:0030198 extracellular matrix organization
GO:0060325 face morphogenesis

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR018244 Allrgn_V5/Tpx1_CS
IPR014044 CAP_domain
IPR035940 CAP_sf
IPR001283 CRISP-related
IPR004043 LCCL
IPR036609 LCCL_sf

PROSITE

PROSITE ID PROSITE Term
PS01010 CRISP_2
PS50820 LCCL

Pfam

Pfam ID Pfam Term
PF00188 CAP
PF03815 LCCL