Gene: ACSS2

Basic information

Tag Content
Uniprot ID E2R0C6
Entrez ID
Genbank protein ID
Genbank nucleotide ID XM_014106885.1
Ensembl protein ID ENSCAFP00000011358
Ensembl nucleotide ID ENSCAFG00000007637
Gene name Acyl-CoA synthetase short chain family member 2
Gene symbol ACSS2
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGLPEERSRS GSGSGEREEA GTRNRVRSWS PPPEVSRSAH VPSLQRYREL HRRSVEQPRE 60
FWGDIAKEFY WKTSCPGPFL QYNFDVTKGK VFIEWMKGAT TNICYNVLDR IVHEKKLGDK 120
VAFYWEGNEP EETTQITYRE LLVQVCRFSN VLQKQGIRKG DRVAIYMPMI PELVVAMLAC 180
ARLGALHSIV FAGFSAESLC ERILDSSCSL LITTDAFYRG EKLVNLKELA DEALEKCREK 240
GFRVRCCIVV KHLGRAELGT GDSPSQSPPI KRPCPNVQGK LKEKPKRIWP QISWNQGVDL 300
WWHELMQEAE DECEPEWCDA EDPLFILYTS GSTGKPKGVV HTVGGYMLYV ATTFKYVFDF 360
HAEDVFWCTA DIGWITGHSY VTYGPLANGA TSVLFEGIPT YPDVSRLWNI VDKYKVTKFY 420
TAPTAIRLLM KFGDEPVTRH SRASLQVLGT VGEPINPEAW LWYHRVVGAQ RCSIVDTFWQ 480
TETGGHMLTP LPGATPMKPG SATFPFFGVA PAILNESGEE LEGEAEGYLV FKQPWPGIMR 540
TVYGNHERFE ATYFKKFPGY YVTGDGCRRD QDGYYWITGR IDDMLNVSGH LLSTAEVESA 600
LVEHEAIAEA AVVGHPHPVK GECLYCFVTL CDGYTFSPTL TEELKKQIRE KIGPIATPDY 660
IQNAPGLPKT RSGKIMRRVL RKIAQNDHDL GDTSTVADPT VICQLFNHRC LTIQ 714

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologACSS2506459A7YWF1Bos taurusPredictionMore>>
1:1 orthologACSS2E2R0C6Canis lupus familiarisPredictionMore>>
1:1 orthologACSS2102169772A0A452FVS4Capra hircusPredictionMore>>
1:1 orthologACSS255902Q9NR19Homo sapiensPublicationMore>>
1:1 orthologAcss260525Q9QXG4Mus musculusPredictionMore>>
1:1 orthologACSS2A0A2J8JYI9Pan troglodytesPredictionMore>>
1:1 orthologACSS2F1S4Y0Sus scrofaPredictionMore>>
1:1 orthologAcss2311569G3V9U0Rattus norvegicusPredictionMore>>
1:1 orthologacss2Q6DHN4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005829 cytosol
GO:0005654 nucleoplasm
GO:0003987 acetate-CoA ligase activity
GO:0050218 propionate-CoA ligase activity
GO:0006085 acetyl-CoA biosynthetic process
GO:0008610 lipid biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR032387 ACAS_N
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf

PROSITE

PROSITE ID PROSITE Term
PS00455 AMP_BINDING

Pfam

Pfam ID Pfam Term
PF16177 ACAS_N
PF00501 AMP-binding
PF13193 AMP-binding_C