Gene: Acss2

Basic information

Tag Content
Uniprot ID G3V9U0
Entrez ID 311569
Genbank protein ID EDL85913.1
Genbank nucleotide ID NM_001107793.1
Ensembl protein ID ENSRNOP00000059987
Ensembl nucleotide ID ENSRNOG00000018755
Gene name Acyl-CoA synthetase short-chain family member 2
Gene symbol Acss2
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MGLPEERRKS GSGSRAREET GAEGRVRGWS PPPEVRRSAH VPSLQRYREL HRRSVEEPRE 60
FWGNIAKEFY WKTPCPGPFL QYNFDVTKGK IFTEWMKGAT TNICYNVLDR NVHEKKLGDK 120
VAFYWEGNEP GETTKITYRE LLVQVCQFSN VLRKQGVQKG DRVAIYMPMI LELVVAMLAC 180
ARLGALHSIV FAGFSAESLC ERILDSSCCL LITTDAFYRG EKLVNLKELA DESLEKCREK 240
GFPVRCCIVV KHLGRAELGM NDSPSQSPPV KRPCPDVQIS WNEGVDLWWH ELMQQAGDEF 300
EPEWCDAEDP LFILYTSGST GKPKGVVHTV GGYMLYVATT FKYVFDFHPE DVFWCTADIG 360
WITGHSYVTY GPLANGATSV LFEGIPTYPD EGRLWSIVDK YKVTKFYTAP TAIRMLMKFG 420
DDPVTKHSRA SLQVLGTVGE PINPEAWLWY HRVVGSQRCP IVDTFWQTET GGHMLTPLPG 480
ATPMKPGSAS FPFFGVAPAI LNESGEELEG EAEGYLVFKQ PWPGIMRTVY GNHTRFETTY 540
FKKFPGYYVT GDGCRRDQDG YYWITGRIDD MLNVSGHLLS TAEVESALVE HEAVAEAAVV 600
GHPHPVKGEC LYCFVTLCDG HTFSPTLTEE LKKQIREKIG PIATPDYIQN APGLPKTRSG 660
KIMRRVLRKI AQNDHDLGDT STVADPSVIN HLFSHRCLTT Q 701

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologACSS2506459A7YWF1Bos taurusPredictionMore>>
1:1 orthologACSS2E2R0C6Canis lupus familiarisPredictionMore>>
1:1 orthologACSS2102169772A0A452FVS4Capra hircusPredictionMore>>
1:1 orthologACSS255902Q9NR19Homo sapiensPublicationMore>>
1:1 orthologAcss260525Q9QXG4Mus musculusPredictionMore>>
1:1 orthologACSS2A0A2J8JYI9Pan troglodytesPredictionMore>>
1:1 orthologACSS2F1S4Y0Sus scrofaPredictionMore>>
1:1 orthologAcss2311569G3V9U0Rattus norvegicusPredictionMore>>
1:1 orthologacss2Q6DHN4Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0016021 integral component of membrane
GO:0005654 nucleoplasm
GO:0003987 acetate-CoA ligase activity
GO:0050218 propionate-CoA ligase activity
GO:0019413 acetate biosynthetic process
GO:0006085 acetyl-CoA biosynthetic process
GO:0008610 lipid biosynthetic process
GO:0019542 propionate biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR032387 ACAS_N
IPR025110 AMP-bd_C
IPR020845 AMP-binding_CS
IPR000873 AMP-dep_Synth/Lig
IPR042099 AMP-dep_Synthh-like_sf

PROSITE

PROSITE ID PROSITE Term
PS00455 AMP_BINDING

Pfam

Pfam ID Pfam Term
PF16177 ACAS_N
PF00501 AMP-binding
PF13193 AMP-binding_C