Gene: BARX1

Basic information

Tag Content
Uniprot ID E2RF36
Entrez ID 610486
Genbank protein ID
Genbank nucleotide ID XM_847999.2
Ensembl protein ID ENSCAFP00000003249
Ensembl nucleotide ID ENSCAFG00000002234
Gene name BARX homeobox 1
Gene symbol BARX1
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MQRPGEPGAA RFGPPEGCAD PPPHRYRSFM IEEILTEPRG PKGAAPAAAA AAAAGELLKF 60
GVQALLAARP FHSHLAVLKA EQAAVFKFPL APLGCSGLGS ALLAAGPGLP GAPSAPHLPL 120
ELQLRGKLET PGPGEPGAKA KKGRRSRTVF TELQLMGLEK RFEKQKYLST PDRIDLAESL 180
GLSQLQVKTW YQNRRMKWKK IVLQGGGLES PTKPKGRPKK NSIPTSEQLT EQERAKEAEK 240
PAEAPGDTID RSRED 255

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologBARX1610486E2RF36Canis lupus familiarisPredictionMore>>
1:1 orthologBARX1A0A452F3S2Capra hircusPredictionMore>>
1:1 orthologBARX156033Q9HBU1Homo sapiensPredictionMore>>
1:1 orthologBarx112022Q9ER42CPOMus musculusPublicationMore>>
1:1 orthologBARX1745472H2R4D7Pan troglodytesPredictionMore>>
1:1 orthologBARX1F1SUC6Sus scrofaPredictionMore>>
1:1 orthologBarx1364680D3ZA67Rattus norvegicusPredictionMore>>
1:1 orthologbarx1553644B2GRF3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0001228 DNA-binding transcription activator activity, RNA polymerase II-specific
GO:0000977 RNA polymerase II regulatory region sequence-specific DNA binding
GO:0048513 animal organ development
GO:0055123 digestive system development
GO:0006357 regulation of transcription by RNA polymerase II
GO:0009888 tissue development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0238 DNA-binding
KW-0371 Homeobox
KW-0539 Nucleus
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR009057 Homeobox-like_sf
IPR017970 Homeobox_CS
IPR001356 Homeobox_dom
IPR020479 Homeobox_metazoa
IPR000047 HTH_motif

PROSITE

PROSITE ID PROSITE Term
PS00027 HOMEOBOX_1
PS50071 HOMEOBOX_2

Pfam

Pfam ID Pfam Term
PF00046 Homeodomain