Gene: SERPINA11

Basic information

Tag Content
Uniprot ID F1PHS2
Entrez ID 490838
Genbank protein ID
Genbank nucleotide ID XM_005623764.2; XM_547960.5;
Ensembl protein ID ENSCAFP00000026021
Ensembl nucleotide ID ENSCAFG00000024668
Gene name Serpin family A member 11
Gene symbol SERPINA11
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MLLALCTYFL WLSTSYLLTV QAKDPDTDVS TSSSHRDLAP KNVDFAFNLY RHLVASSPDK 60
NVFISPVSIS MALAMLSLGA CGYTRVQLLQ GLGFNLTKMS EAEIHQGFRH LRHLLEKSDT 120
MLEMTMGNAL FLDRSLELLE PFSADTKHYY DLEAWATDFQ DGTGASRQIN EYIKNKTQGK 180
IVDLLSKLDS SAMVILVNYI FFKGTWEHPF DPESTREEDF YVNETTVVRV PTMFQSSTIK 240
HLNDQVLPCQ LVQLEYMGNG TVFFILPEEG KMDTVIAALS RDTIQRWSES FTRSQVNLYI 300
PKVSLSGAYD LRAILRDMGI ADLLDNGADF SGMTREAQPK LSKVVHKAVL QLHEKGLEAA 360
GPAGVMPNVK SEPLAFHFNR PFIVMIFDHF TWSSLFLGKV VNPT 404

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSERPINA6513746E1BF81Bos taurusPredictionMore>>
1:1 orthologSERPINA11490838F1PHS2Canis lupus familiarisPredictionMore>>
1:1 orthologSERPINA6102171661A0A452FGE5Capra hircusPredictionMore>>
1:1 orthologSERPINA6866P08185Homo sapiensPublicationMore>>
1:1 orthologSerpina612401Q06770Mus musculusPredictionMore>>
1:1 orthologSERPINA6453131H2Q8V1Pan troglodytesPredictionMore>>
1:1 orthologSerpina6299270P31211Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0010951 negative regulation of endopeptidase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome
KW-0732 Signal

Interpro

InterPro ID InterPro Term
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
IPR042178 Serpin_sf_1
IPR042185 Serpin_sf_2

PROSITE

PROSITE ID PROSITE Term
PS00284 SERPIN

Pfam

Pfam ID Pfam Term
PF00079 Serpin