Gene: SERPINA6

Basic information

Tag Content
Uniprot ID H2Q8V1; A0A2J8QMQ9;
Entrez ID 453131
Genbank protein ID
Genbank nucleotide ID XM_510143.6
Ensembl protein ID ENSPTRP00000011384
Ensembl nucleotide ID ENSPTRG00000006678
Gene name Serpin family A member 6
Gene symbol SERPINA6
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPLLLYTCLL WLSTSGLWTV QAMDPNAAYV NMSNHHRGLA SANVDFAFSL YKHLVALSPK 60
KNIFISPVSI SMALAMLSLG TCGHTRAQLL QGLGFNLTER SETEIHQGFQ HLHQLFAKSD 120
TSLEMTMGNA LFLDGSLELL QSFSADIKHY YESEVLATNF QDWATASRQI NSYVKSKTQG 180
KIADLLSGLD SPAILVLVNY IFFKGTWTQP FDLASTREDN FYVDETTVVK VPMMLQSSII 240
SYLHDSELPC QLVQMNYVGN GTVFFILPDK GKMNTVIAAL SRDTINRWSA GLTSSQVDLY 300
IPKVTISGVY DLGDVLEEMG IADLFTNQAN FSRITQDAQL KSSKVVHKAV LQLNEEGVDT 360
AGSTGVTLNL TSKPIILRFN QPFIIMIFDH FTWSSLFLAR VMNPV 405

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSERPINA6513746E1BF81Bos taurusPredictionMore>>
1:1 orthologSERPINA11490838F1PHS2Canis lupus familiarisPredictionMore>>
1:1 orthologSERPINA6102171661A0A452FGE5Capra hircusPredictionMore>>
1:1 orthologSERPINA6866P08185Homo sapiensPublicationMore>>
1:1 orthologSerpina612401Q06770Mus musculusPredictionMore>>
1:1 orthologSERPINA6453131H2Q8V1Pan troglodytesPredictionMore>>
1:1 orthologSerpina6299270P31211Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005615 extracellular space
GO:0004867 serine-type endopeptidase inhibitor activity
GO:0005496 steroid binding
GO:0008211 glucocorticoid metabolic process
GO:0010951 negative regulation of endopeptidase activity

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR023795 Serpin_CS
IPR023796 Serpin_dom
IPR000215 Serpin_fam
IPR036186 Serpin_sf
IPR042178 Serpin_sf_1
IPR042185 Serpin_sf_2

PROSITE

PROSITE ID PROSITE Term
PS00284 SERPIN

Pfam

Pfam ID Pfam Term
PF00079 Serpin