| Tag | Content |
|---|---|
| Uniprot ID | F1Q5T3 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000069753 |
| Ensembl nucleotide ID | ENSDARG00000011190 |
| Gene name | Fibroblast growth factor receptor 1b |
| Gene symbol | fgfr1b |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MIFLSAAVSL RMLKSWRLLV LLLILTQLCT VQSRPAVTEQ GHIVASSEDE DDDESSSEEN 60 KPSSSQELLP MAPRWAQPEK MEKKLHAVPA SKTVKFRCQA EGNPIPKLRW LKNGKEFKRD 120 QRIGGYKLRE HMWTIIMESV VPSDKGNYTC LVENEYGSIN HTYQLDVVER SPHRPILYAG 180 LPANRTAVVG SDVEFVCKVF SDPQPHIQWL KHIRVNGSQL GPDGLPYVRV LKTAGLNTTD 240 KEMEVLQLRN VSFEDAGEYT CLAGNSIGIS HHSAWLTVVK |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | FGFR1 | 281768 | A4IFL5 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | FGFR1 | 100856477 | A0A5F4CQJ1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | FGFR1 | A0A452E6I8 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | FGFR1 | 2260 | P11362 | CL/P | Homo sapiens | Publication | More>> | |
| 1:1 ortholog | Fgfr1 | 14182 | P16092 | CPO | E14.5, E16.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | FGFR1 | A0A2I3RMA9 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Fgfr1 | F1LM54 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | fgfr1b | F1Q5T3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005887 | integral component of plasma membrane |
| GO:0043235 | receptor complex |
| GO:0017134 | fibroblast growth factor binding |
| GO:0005007 | fibroblast growth factor-activated receptor activity |
| GO:0004714 | transmembrane receptor protein tyrosine kinase activity |
| GO:0008543 | fibroblast growth factor receptor signaling pathway |
| GO:0007275 | multicellular organism development |
| GO:0045597 | positive regulation of cell differentiation |
| GO:0033674 | positive regulation of kinase activity |
| GO:0036342 | post-anal tail morphogenesis |
| GO:0007169 | transmembrane receptor protein tyrosine kinase signaling pathway |
| PROSITE ID | PROSITE Term |
|---|---|
| PS50835 | IG_LIKE |
| Pfam ID | Pfam Term |
|---|---|
| PF07679 | I-set |