| Tag | Content |
|---|---|
| Uniprot ID | F1RC47 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSDARP00000156756; ENSDARP00000042943; |
| Ensembl nucleotide ID | ENSDARG00000036956; ENSDARG00000115751; |
| Gene name | ASXL transcriptional regulator 1 |
| Gene symbol | asxl1 |
| Organism | Danio rerio |
| NCBI taxa ID | 7955 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MLHSQVRGDR VKNSIFFKLP GRMSLFTLKK NALQWTKSPS ANESGDGTPT ASTTSTVEGA 60 EQESCDSTET AAASGENDAS VDETSSSASC STEPQTRLSR SSQSGRQRKK AVMMPRVVLT 120 PLKVNGEHVP SGAAGRRREG SRGGPGPTLR TRSELGWKRT QHFKSIRGLR SGPMKRSRGG 180 VEVDFETPGS ILVNTNIRAL INTRTFAAFP SHSQQQLLQL LPEVDRQVGP DGLARLSSSA 240 LNNEFFTHAS QSWKERLAEG EFTHEMQVRF RQEMEKEKKV EAWKEKFFEE YHGQRSGLTR 300 EEALKLTMSE AGDVASPVLD SDSATVATPK RRSVGRRRRE GRIRRRSRAD LRRRARRTLC 360 KTTTATVATE ETTESTATPE EVPSVASPVP ETTAVQGEVV LQTDPELEAP EENLSTEAVP 420 SPVPVPTPPP ASTSSTCDEP ETSTRLLPEV PEPAVASTSS PSSSSSSTSS SSSPSSSPSS 480 ASDRQTFAAS SDSSSSSSSS TAAVATDPLD DGASVITTGT AGTGASSRES SPAASPATSS 540 PAIQLKEQKR RPDESQAFTS FPEKRARLDE RQSFRNTVDC VHSEKPQPTT EEPKVPPIRI 600 QLSRIKPPWV KGPPTYQICP RIVPPNEGSR RSGTGARTLA DIKARAQQAR AQREAAAAVA 660 ASGDGGGPGG SGPGGGTGIP DRSSGRRTRE HPGPVEPGGG GGRRGGRVDL EEQESPASSH 720 SSGAQLQLSS VDSADRPQTS TPLTEPSPSS VSSNPSLPSS ESPKILALSP PATDSPASQD 780 QVEEICGVEE VTACPSDKTS EQTLDTPVPT PSESESFCSH QDGRGEEAES SDSRTNTPVC 840 TSSSNDAISL VPTSIPDSLP RFGAQGVDVI RTLAASSQPW EGEKKAVELH PGTTGVIQHG 900 SDLKLPKETL VTARNGWVEN REEHSMREGM LEEHRNGGSD ANGKYESGSL PCLPRCAGEE 960 DTGAHSDSTE TASDFENESQ EDEMVDWHGT QMDGSGMQTQ NTKSLNRPVI QTSSRLTSSI 1020 VNPPQHQQPV IQAHISNQNH TQTVIQACFP NGVPNQPVIH PHKQHAINTH AINHSQDQIA 1080 SAPSQAQVQA YLTQTEMDQS RNLRLNDNGN GVKLYLSEDD TKPLGREDLV LKNSAGPPVG 1140 RRVQVSSRPV STVEANNPLV TQLLQGSLPL EKVLPQPHSA SKLEINRLPG ANSSNSLNPA 1200 NHQTQRNLAP RFRGPPESGG PTDTVSSDFQ HKTPPARVSP GPGRNFGSSP PGSAPSRMAC 1260 LFEEASPRSA NSQFSSQQPG GVVPPGAVPV ITSLPLNSTT RTSMDMNSQN APVYESAVIK 1320 EHPGPLSQRS ETPERPSSFQ QHPNNVSQSV CRNTPDAPSP PHGDLCPSEV VPTVKINWRP 1380 NKPQQPISPV ATVKNEVSLR PSCQQALTKN SPAPISGNTS VVITKKEPLD GFHGGGGAME 1440 GLLNMEMSLV RMAKKEQVKN PYTRQADTSA SPVSSSPSSS ASSLPFQLYG KLPKLQQSGG 1500 NGGSSSSFSY TANVSVVDGS GFTRTLADSV LQLRPRVSVG SGGGQSATLG IQAFTDSAAE 1560 EVALKCSCRL KAMIMCQGCG AFCHDDCIGP SKLCVSCLVV R 1601 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ASXL1 | A0A452G2F5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | ASXL1 | 171023 | Q8IXJ9 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Asxl1 | 228790 | P59598 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ASXL1 | H2R3B7 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | Asxl1 | A0A0G2JU33 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | asxl1 | F1RC47 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0035517 | PR-DUB complex |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0046872 | metal ion binding |
| GO:0042975 | peroxisome proliferator activated receptor binding |
| GO:0009887 | animal organ morphogenesis |
| GO:0045944 | positive regulation of transcription by RNA polymerase II |