| Tag | Content |
|---|---|
| Uniprot ID | F1S615 |
| Entrez ID | |
| Genbank protein ID | |
| Genbank nucleotide ID | |
| Ensembl protein ID | ENSSSCP00000007266 |
| Ensembl nucleotide ID | ENSSSCG00000006812 |
| Gene name | ALX homeobox 3 |
| Gene symbol | ALX3 |
| Organism | Sus scrofa |
| NCBI taxa ID | 9823 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MDPERCAPFG VGPESGPYAA AGDEPPGPQR TPAAAPHLHP APPRGPRLTR FPACGPLEPY 60 LPEPAKPPAK YLQDLGPGPA LNGGHFYEGP AEAEEKASKA ASFPQLPLDC RGGPRDGPSN 120 LPGSPGPCLA SLRVPLSPGL PDSMELAKNK SKKRRNRTTF STFQLEELEK VFQKTHYPDV 180 YAREQLALRT DLTEARVQVW FQNRRAKWRK RERYGKIQEG RNPFTSAYDI SVLPRTDSHP 240 QLQNALWPSP GSGSPGGPCL VSPEGIPSPC MSPYPHSHGN VAGFMGVPAS PGAPPSIYSI 300 HSFSPALGAH SFEPSPDGDY KSPSLISLRV KPKEPPNLLN WTT 343 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | ALX3 | 102184773 | A0A452G5Q5 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | ALX3 | 257 | O95076 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Alx3 | 11694 | O70137 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | ALX3 | 469416 | H2PZM0 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | ALX3 | F1S615 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | ALX3 | 100355559 | G1SXT4 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | Alx3 | F1LN97 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0000981 | DNA-binding transcription factor activity, RNA polymerase II-specific |
| GO:0000977 | RNA polymerase II regulatory region sequence-specific DNA binding |
| GO:0048701 | embryonic cranial skeleton morphogenesis |
| GO:0035115 | embryonic forelimb morphogenesis |
| GO:0035116 | embryonic hindlimb morphogenesis |
| GO:0007389 | pattern specification process |
| GO:0042981 | regulation of apoptotic process |
| Pfam ID | Pfam Term |
|---|---|
| PF00046 | Homeodomain |