Gene: TSHZ1

Basic information

Tag Content
Uniprot ID F1SNN4
Entrez ID
Genbank protein ID HDB10641.1; HDB41727.1;
Genbank nucleotide ID
Ensembl protein ID ENSSSCP00000005234
Ensembl nucleotide ID ENSSSCG00000004861
Gene name Teashirt homolog 1 isoform 1
Gene symbol TSHZ1
Organism Sus scrofa
NCBI taxa ID 9823
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPRRKQQAPR RSAAYVPEEE LKAAEIDEEN GEEDGLPLDL QEGDYACNEE TEIKEAQSYQ 60
NSPVSTATNQ DAGYGSPFSE NSDQLAHLKS SSSREEKEEP PGPESVSYPQ DSLAQIKAVY 120
ANLFSESCWS SLALDLKKSS STTSNSDVGQ KEGSTPAPTP PTSTSGATGT TASTPSSGAA 180
SGSGTSTSSS GGGGGSGYDW HQAALAKTLQ QTSSYGLLPE PSLFSTVQLY RQNNKLYGSV 240
FTGASKFRCK DCSAAYDTLV ELTVHMNETG HYRDDNRDKD SEKTKRWSKP RKRSLMEMEG 300
KEDAQKVLKC MYCGHSFESL QDLSVHMIKT KHYQKVPLKE PVPAITKLVP STKKRALQDL 360
AAPCSPEPAG IAVEASLSES AKDQKAANPY VTPNNRYGYQ NGASYTWQFE ARKAQILKCM 420
ECGSSHDTLQ QLTAHMMVTG HFLKVTTSAS KKGKQLVLDP VVEEKIQSIP LPPTTHTRLP 480
AAHIKKQPDS PAGSTTSEEK KEPEKEKAPV VAPAGEVDKK IKEEGEDSSE KFEPTALYQY 540
LREEDLDDSP RGGVDILKSL ENTVSTAISK AQNGAPSWGG YPSIHAAYQL PGTVKPLPAV 600
QSVQMQPSYA SSVKSLSSEH SALLHSPGSL TPPPHKSNVS AMEELVEKVT GKVSVKKEER 660
PVEKEKGSPA KAVSPVAKEN KDFPRTEEPS NGKPQPKKGP EADAGKAKKE GAGDAHTPNG 720
TEPLKAKVTN GCNNLGIITD HSPEPSFINP LSALQSIMNT HLGKVSRPVS PSLDPLAMLY 780
KISTSMLDKP AYPAMPAKPP GALDRYYYEN SDQPIDLTKS KSKPLVSGAA DGVASPLRES 840
ALMDISDMVK NLTGRLTPKS STPSTVSEKS DADGSSFEEA LDELSPVHKR KGRQSNWNPQ 900
HLLILQAQFA SSLRETPEGK YIMSDLGPQE RVHISKFTGL SMTTISHWLA NVKYQLRRTG 960
GTKFLKNLDT GHPVFFCNDC ASQFRTASTY INHLETHLGF SLKDLSKLPL NQIQEQQNVS 1020
KVLANKALGP VGASEEDLGS TFQCKLCNRT FASKHAVKLH LSKTHGKSPE DHLIYVTELE 1080
KQ 1082

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTSHZ1102179155A0A452EVF0Capra hircusPredictionMore>>
1:1 orthologTSHZ110194Q6ZSZ6Homo sapiensPredictionMore>>
1:1 orthologTshz1110796Q5DTH5CPOMus musculusPublicationMore>>
1:1 orthologTSHZ1455478H2QEQ4Pan troglodytesPredictionMore>>
1:1 orthologTSHZ1F1SNN4Sus scrofaPredictionMore>>
1:1 orthologTshz1F1LW29Rattus norvegicusPredictionMore>>
1:1 orthologtshz1369196F6NU84Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003682 chromatin binding
GO:0003677 DNA binding
GO:0009952 anterior/posterior pattern specification
GO:0042474 middle ear morphogenesis
GO:0006357 regulation of transcription by RNA polymerase II
GO:0060023 soft palate development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0479 Metal-binding
KW-1185 Reference proteome
KW-0862 Zinc
KW-0863 Zinc-finger

Interpro

InterPro ID InterPro Term
IPR001356 Homeobox_dom
IPR027008 Teashirt_fam
IPR026808 Tshz1
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS00028 ZINC_FINGER_C2H2_1
PS50157 ZINC_FINGER_C2H2_2

Pfam

Pfam ID Pfam Term