Gene: TSHZ1

Basic information

Tag Content
Uniprot ID H2QEQ4
Entrez ID 455478
Genbank protein ID
Genbank nucleotide ID XM_001137580.4
Ensembl protein ID ENSPTRP00000017195
Ensembl nucleotide ID ENSPTRG00000010120
Gene name Teashirt zinc finger homeobox 1
Gene symbol TSHZ1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MERGPRAGPP SARCCAAARA GDDSAARRPG PARSARSPAA GTRPRGRRRR LLSGPRRGGP 60
CELGSPRSAA LPEPGARGDE AKVGRAAELR PRPGPRVPAP RELRRRLRRR LRRPSSMPRR 120
KQQAPRRSAA YVPEEELKAA EIDEEHVEDD GLSLDIQESE YMCNEETEIK EAQSYQNSPV 180
SSVTNQDAGY GSPFSESSDQ LAHFKGSSSR EEKEDPQCPD SVSYPQDSLA QIKAVYANLF 240
SESCWSSLAL DLKKSGSTTS TNDASQKESS APTPTPPTCP VSTTGPTTST PSTSCSSSTT 300
HSSTTSTSSS SGYDWHQAAL AKTLQQTSSY GLLPEPSLFS TVQLYRQNNK LYGSVFTGAS 360
KFRCKDCSAA YDTLVELTVH MNETGHYRDD NRDKDSEKTK RWSKPRKRSL MEMEGKEDAQ 420
KVLKCMYCGH SFESLQDLSV HMIKTKHYQK VPLKEPVPAI TKLVPSTKKR ALQDLAPPCS 480
PEPAGMAAEV ALSESAKDQK AANPYVTPNN RYGYQNGASY TWQFEARKAQ ILKCMECGSS 540
HDTLQQLTAH MMVTGHFLKV TTSASKKGKQ LVLDPVVEEK IQSIPLPPTT HTRLPASSIK 600
KQPDSPAGST TSEEKKEPEK EKPPVAGDAE KIKEESEDSL EKFEPSTLYP YLREEDLDDS 660
PKGGLDILKS LENTVSTAIS KAQNGAPSWG GYPSIHAAYQ LPGTVKPLPA AVQSMQVQPS 720
YAGGVKSLSS AEHNALLHSP GSLTPPPHKS NVSAMEELVE KVTGKVNIKK EERPPEKEKS 780
SPAKAASPIA KENKDFPKTE EVSGKPQKKG PEAETGKAKK EGPLDVHTPN GTEPLKAKVT 840
NGCNNLGIIT DHSPEPSFIN PLSALQSIMN THLGKVSKPV SPSLDPLAML YKISNSMLDK 900
PVYPATPVKQ ADAIDRYYYE NSDQPIDLTK SKNKPLVSSV ADSVASPLRE SALMDISDMV 960
KNLTGRLTPK SSTPSTVSEK SDADGSSFEE ALDELSPVHK RKGRQSNWNP QHLLILQAQF 1020
ASSLRETTEG KYIMSDLGPQ ERVHISKFTG LSMTTISHWL ANVKYQLRRT GGTKFLKNLD 1080
TGHPVFFCND CASQFRTAST YISHLETHLG FSLKDLSKLP FNQIQEQQNV SKVLTNKTLG 1140
PLGATEEDLG STFQCKLCNR TFASKHAVKL HLSKTHGKSP EDHLIYVTEL EKQ 1193

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologTSHZ1102179155A0A452EVF0Capra hircusPredictionMore>>
1:1 orthologTSHZ110194Q6ZSZ6Homo sapiensPredictionMore>>
1:1 orthologTshz1110796Q5DTH5CPOMus musculusPublicationMore>>
1:1 orthologTSHZ1455478H2QEQ4Pan troglodytesPredictionMore>>
1:1 orthologTSHZ1F1SNN4Sus scrofaPredictionMore>>
1:1 orthologTshz1F1LW29Rattus norvegicusPredictionMore>>
1:1 orthologtshz1369196F6NU84Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005634 nucleus
GO:0003682 chromatin binding
GO:0003677 DNA binding
GO:0009952 anterior/posterior pattern specification
GO:0042474 middle ear morphogenesis
GO:0006357 regulation of transcription by RNA polymerase II
GO:0060023 soft palate development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR001356 Homeobox_dom
IPR027008 Teashirt_fam
IPR026808 Tshz1
IPR013087 Znf_C2H2_type

PROSITE

PROSITE ID PROSITE Term
PS00028 ZINC_FINGER_C2H2_1
PS50157 ZINC_FINGER_C2H2_2

Pfam

Pfam ID Pfam Term