| Tag | Content |
|---|---|
| Uniprot ID | Q5DTH5; Q6PE60; Q8VD19; Q9JLD5; |
| Entrez ID | 110796 |
| Genbank protein ID | AAH58264.1; AAH17636.1; AAF63158.1; BAD90534.1; |
| Genbank nucleotide ID | NM_001081300.1 |
| Ensembl protein ID | ENSMUSP00000089388 |
| Ensembl nucleotide ID | ENSMUSG00000046982 |
| Gene name | Teashirt homolog 1 |
| Gene symbol | Tshz1 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | CPO |
| Developmental stage | |
| Data sources | Manually collected |
| Reference | 17586487 |
| Functional description | Probable transcriptional regulator involved in developmental processes. May act as a transcriptional repressor (Potential). |
| Sequence | MPRRKQQAPR RSAAYVPEEE LKAAEIDEEH AEDGGLSLDI QESEFACNEE TEIKEAQSYQ 60 NSPVSTATNQ DAGYGSPFSE GSDQLAHFKS SSSREEKEES QCPDSVSYPQ DSLAQIKAVY 120 ANLFSESCWS SLALDLKKSN SATSNNDASQ KESSTPTPTP PTSTASTACT TATTAITSCS 180 TSTSHSSTTS NSSSSGYDWH QAALAKTLQQ TSSYGLLPEP SLFSTVQLYR QNNKLYGSVF 240 TGASKFRCKD CSAAYDTLVE LTVHMNETGH YRDDNRDKDS EKTKRWSKPR KRSLMEMEGK 300 EDAQKVLKCM YCGHSFESLQ DLSVHMIKTK HYQKVPLKEP VPAITKLVPS TKKRALQDLA 360 SPCSPEPTGV ATEVALSESA KDQKTANPYV TPNNRYGYQN GASYTWQFEA RKAQILKCME 420 CGSSHDTLQQ LTAHMMVTGH FLKVTTSASK KGKQLVLDPV VEEKIQSIPL PPTTHTRLPA 480 SSIKKQPDSP AGSVASEEKK EPEKEKEKEK APPAAGDAER KIKEETEDAT EKFEPTALYQ 540 YLREEDLDDS PKGGVDILKS LENTVSTAIS KAQNGAPSWG GYPSIHAAYQ LPGTVKPLQS 600 AVQSVQIQPS YASSVKSLSS TEHNALLHSP GSLTPPPHKS NVSAMEELVE KVTGKVSIKK 660 EERPTEKEKS SPVKAISPVA KENKDLPKTE ETGSKPQKKG SDSETGKAKK ESTLDAHTPN 720 GTEPLKAKVT NGCGHLGIIT DHSPEPSFIN PLSALQSIMN THLGKVSKPV SPSLDPLAML 780 YKISNSMLDK PVYPTTPAKQ ADAIDRYYYE NSDQPIDLTK SKNKPLVSGV ADAVSSPLRE 840 SALMDISDMV KNLTGRLTPK SSTPSTVSEK SDADGSSFEE ALDELSPVHK RKGRQSNWNP 900 QHLLILQAQF ASSLRETAEG KYIMSDLGPQ ERVHISKFTG LSMTTISHWL ANVKYQLRRT 960 GGTKFLKNLD TGHPVFFCND CASQFRTAST YVSHLETHLG FSLKDLSKLP LSQIQEQQSV 1020 VSKALTNKTL GPLGSSEEDL GSTFQCKLCN RTFASKHAVK LHLSKTHGKS PEDHLIYVTE 1080 LEKQ 1084 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | TSHZ1 | 102179155 | A0A452EVF0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | TSHZ1 | 10194 | Q6ZSZ6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Tshz1 | 110796 | Q5DTH5 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | TSHZ1 | 455478 | H2QEQ4 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | TSHZ1 | F1SNN4 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Tshz1 | F1LW29 | Rattus norvegicus | Prediction | More>> | |||
| 1:1 ortholog | tshz1 | 369196 | F6NU84 | Danio rerio | Prediction | More>> |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0003677 | DNA binding | IEA |
| GO:0003682 | chromatin binding | IBA |
| GO:0005515 | protein binding | IPI |
| GO:0046872 | metal ion binding | IEA |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0006357 | regulation of transcription by RNA polymerase II | IBA |
| GO:0009952 | anterior/posterior pattern specification | IMP |
| GO:0042474 | middle ear morphogenesis | IMP |
| GO:0060023 | soft palate development | IMP |
| GO ID | GO Term | Evidence |
|---|---|---|
| GO:0005634 | nucleus | IBA |
| Reactome ID | Reactome Term | Evidence |
|---|