Gene: GLG1

Basic information

Tag Content
Uniprot ID F6V9R9
Entrez ID 479654
Genbank protein ID
Genbank nucleotide ID XM_536786.5
Ensembl protein ID ENSCAFP00000032284
Ensembl nucleotide ID ENSCAFG00000020113
Gene name Golgi glycoprotein 1
Gene symbol GLG1
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAACGRVRRM FRLSAALQLL LLAAAGAQKL TGQGGHGQGQ GPGANFPSFV GQPGGGGPAG 60
QPLLQLPQSS QLQHQQQQQQ QQQQQQQPPQ PPQPPFPAGG PPARRGGAGP GGAGGGWKLA 120
EEESCREDVT RVCPKHTWSN NLAVLECLQD VREPENEISS DCNHLLWNYK LNLTTDPKFE 180
SVAREVCKST ISEIKECADE PVGKGYLVSC LVDHRGNITE YQCHQYITKM TAIIFSDYRL 240
ICGFMDDCKN DINILKCGSI RLGEKDAHSQ GEVVSCLEKG LVKEAEERDP KIQVSELCKK 300
AILRVAELSS DDFHLDRHLY FACRDDRERF CENTQAGEGR VYKCLFNHKF EESMSEKCRE 360
ALTTRQKLIA QDYKVSYSLA KSCKSDLKKY RCNVENLPRS REARLSYLLM CLESAVHRGR 420
QVSSECQGEM LDYRRMLMED FSLSPEIILS CRGEIEHHCS GLHRKGRTLH CLMKVVRGEK 480
GSLGMNCQQA LQTLIQETDP GADYRIDRAL NEACESVIQT ACKHIRSGDP MILSCLMEHL 540
YTEKMVEDCE HRLLELQYFI SRDWKLDPVL YRKCQGDASR LCHTHGWNET SELMPPGAVF 600
SCLYRHAYRT EEQGRRLSRE CRAEVQRILH QRAMDVKLDP ALQDKCLIDL GKWCSEKTET 660
GQELECLQDH LDDLAVECRD IVGNLTELES EDIQIEALLM RACEPIIQNF CHDVADNQID 720
SGDLMECLIQ NKHQKDMNEK CAIGVTHFQL VQMKDFRFSY KFKMACKEDV LKLCPNIKKK 780
VDVVICLSTT VRNDTLQEAK EHRVSLKCRK QLRVEELEMT EDIRLEPDLY EACKTDIKNY 840
CSTVQYGNAQ IIECLKENKK QLSTRCHQKV FKLQETEMMD PELDYTLMRV CKQMIKRFCP 900
EADSKTMLQC LKQNKNSELM DPKCKQMITK RQITQNTDYR LNPVLRKACK ADIPKFCHGI 960
LTKAKDDSEL EGQVISCLKL RYADQRLSSD CEDQIRIIIQ ESALDYRLDP QLQLHCSDEI 1020
SNLCAEEAAA QEQTGQVEEC LKVNLLKIKT DTCKKEVLNM LKESKADIFV DPVLHTACAL 1080
DIKHHCAAIT PGRGRQMSCL MEALEDKRVR LQPECKKRLN DRIEMWSYAA KVAPADGFSD 1140
LAMQVMTSPS KNYILSVISG SICILFLIGL MCGRITKRVT RELKDR 1186

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGLG1479654F6V9R9Canis lupus familiarisPredictionMore>>
1:1 orthologGLG1A0A452E1L5Capra hircusPredictionMore>>
1:1 orthologGLG1F6Z3Z4Equus caballusPredictionMore>>
1:1 orthologGLG12734Q92896Homo sapiensPredictionMore>>
1:1 orthologGlg120340Q61543CPOMus musculusPublicationMore>>
1:1 orthologGLG1A0A2I3TER7Pan troglodytesPredictionMore>>
1:1 orthologGLG1G1SJQ2Oryctolagus cuniculusPredictionMore>>
1:1 orthologGlg1G3V8G5Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0031012 extracellular matrix
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0017134 fibroblast growth factor binding
GO:0060349 bone morphogenesis
GO:0010955 negative regulation of protein processing
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032330 regulation of chondrocyte differentiation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0472 Membrane
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR001893 Cys-rich_GLG1_repeat
IPR017873 Cys-rich_GLG1_repeat_euk
IPR039728 GLG1

PROSITE

PROSITE ID PROSITE Term
PS51289 GLG1_C_RICH

Pfam

Pfam ID Pfam Term
PF00839 Cys_rich_FGFR