Gene: Glg1

Basic information

Tag Content
Uniprot ID G3V8G5
Entrez ID
Genbank protein ID EDL92563.1
Genbank nucleotide ID
Ensembl protein ID ENSRNOP00000025570
Ensembl nucleotide ID ENSRNOG00000018668
Gene name Golgi apparatus protein 1
Gene symbol Glg1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAVCGRVRRM FRLSAALQLL LLVAAGVQNS HGQGQGPGVN FGPFAGQAGG GNPVGQQPPQ 60
LPQLSQQQQQ QQPPPQQQQP FPAGGLPARR GGAGPGGTGG GWKLAEEESC REDVTRVCPK 120
HTWSNNLAVL ECLQDVREPE NEISSDCNHL LWNYKLNLTT DPKFESVARE VCKSTISEIK 180
ECAEEPVGKG YMVSCLVDHR GNITEYQCHQ YITKMTAIIF SDYRLICGFM DDCKNDINLL 240
KCGSIRLGEK DAHSQGEVVS CLEKGLVKEA EEKEPKIQVS ELCKKAILRV AELSSDDFHL 300
DRHLYFACRD DRERFCENTQ AGEGRVYKCL FNHKFEESMS EKCREALTTR QKLIAQDYKV 360
SYSLAKSCKS DLKKYRCNVE NLPRSREARL SYLLMCLESA VHRGRQVSSE CQGEMLDYRR 420
MLMEDFSLSP EIILSCRGEI EHHCSGLHRK GRTLHCLMKV VRGEKGSLGM NCQQALQTLI 480
QETDPGADYR IDRALNEACE SVIQTACKHI RSGDPMILSC LMEHLYTEKM VEDCEHRLLE 540
LQYFISRDWK LDPVLYRKCQ GDASRLCHTH GWNETSELMP PGAVFSCLYR HAYRTEEQGR 600
RLSRECRAEV QRILHQRAMD VKLDPALQDK CLIDLGKWCS EKTETGQELE CLQDHLDDLA 660
VECRDIVGNL TELESEDIQI EALLMRACEP IIHNFCHDVA DNQIDSGDLM ECLIQNKHQK 720
DMNEKCAIGV THFQLVQMKD FRFSYKFKMA CKEDVLKLCP NIKKKVDVVI CLSTTVRNDT 780
LQEAKEHRVS LKCRKQLRVE ELEMTEDIRL EPDLYEACKS DIKNYCSTVQ YGNAQIIECL 840
KENKKQLSTR CHQRVFKLQE TEMMDPELDY TLMRVCKQMI KRFCPEADSK TMLQCLKQNK 900
NSELMDPKCK QMITKRQITQ NTDYRLNPVL RKACKADIPK FCHGILTKAK DDSELEGQVI 960
SCLKLRYADQ RLSSDCEDQI RIIIQESALD YRLDPQLQLH CSDEIANLCA EEAAAQEQTG 1020
QVEECLKVNL LKIRTELCKK EVLNMLKESK ADIFVDPVLH TACALDIKHH CAAITPGRGR 1080
QMSCLMEALE DKRVRLQPEC KKRLNDRIEM WSYAAKVAPA DGFSDLAMQV MTSPSKNYIL 1140
SVISGSICIL FLIGLMCGRI TKRVTRELKD R 1171

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologGLG1479654F6V9R9Canis lupus familiarisPredictionMore>>
1:1 orthologGLG1A0A452E1L5Capra hircusPredictionMore>>
1:1 orthologGLG1F6Z3Z4Equus caballusPredictionMore>>
1:1 orthologGLG12734Q92896Homo sapiensPredictionMore>>
1:1 orthologGlg120340Q61543CPOMus musculusPublicationMore>>
1:1 orthologGLG1A0A2I3TER7Pan troglodytesPredictionMore>>
1:1 orthologGLG1G1SJQ2Oryctolagus cuniculusPredictionMore>>
1:1 orthologGlg1G3V8G5Rattus norvegicusPredictionMore>>

Gene ontology

GO ID GO Term
GO:0031012 extracellular matrix
GO:0000139 Golgi membrane
GO:0016021 integral component of membrane
GO:0060349 bone morphogenesis
GO:0010955 negative regulation of protein processing
GO:0030512 negative regulation of transforming growth factor beta receptor signaling pathway
GO:0032330 regulation of chondrocyte differentiation

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0472 Membrane
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0732 Signal
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR001893 Cys-rich_GLG1_repeat
IPR017873 Cys-rich_GLG1_repeat_euk
IPR039728 GLG1

PROSITE

PROSITE ID PROSITE Term
PS51289 GLG1_C_RICH

Pfam

Pfam ID Pfam Term
PF00839 Cys_rich_FGFR