| Tag | Content |
|---|---|
| Uniprot ID | F7CLC3 |
| Entrez ID | 100049999 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_005613976.2; XM_005613975.2; XM_014728758.1; |
| Ensembl protein ID | ENSECAP00000017531 |
| Ensembl nucleotide ID | ENSECAG00000019648 |
| Gene name | Midline 1 |
| Gene symbol | MID1 |
| Organism | Equus caballus |
| NCBI taxa ID | 9796 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | METLESELTC PICLELFEDP LLLPCAHSLC FNCAHRILVS HCATNESVES ITAFQCPTCR 60 HVITLSQRGL DGLKRNVTLQ NIIDRFQKAS VSGPNSPSET RRERAFDANT MTSAEKVLCQ 120 FCDQDPAQDA VKTCVTCEVS YCDECLKATH PNKKPFTGHR LIEPIPDSHI RGLMCLEHED 180 ERVNMYCVTD DQLICALCKL VGRHRDHQVA ALSERYDKLK QNLESNLTSL IKRNTELETL 240 LAKLIQTCQH VEVNASRQEA KLMEECDLLI EIIQQRRQII GTKIKEGKVM RLRKLAQQIA 300 NCKQCIERSA SLISQAEHSL KENDHARFLQ TAKNITERVS MATASSQVLI PEINLNDTFD 360 TFALDFSREK KLLECLDYLT APNPPTIREE LCTASYDTIT VHWTSDDEFS VVSYELQYTI 420 FTGQANVVSL CNSADSWMIV PNIKQNHYTV HGLQSGTKYI FIVKAINQAG SRSSEPGKLK 480 TNSQPFKLDP KSAHRKLKVS HDNLTVERDE SSSKKSHTPE RFTSQGSYGV AGNVFIDSGR 540 HYWEVVISGS TWYAIGLAYK SAPKHEWIGK NSASWALCRC HNNWVVRHNS KEIPIEPAPH 600 LRRVGILLDY DNGSIAFYDA LNSIHLYTFD ITFSQPVCPT FTVWNKCLTI ITGLPIPDHL 660 DCTEQLP 667 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | MID1 | 534604 | E1BAD8 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | MID1 | 491737 | A0A5F4CNE1 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | MID1 | 102174822 | A0A452EDX1 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | MID1 | 100049999 | F7CLC3 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | MID1 | 4281 | O15344 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Mid1 | 17318 | O70583 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | MID1 | H2QYA1 | Pan troglodytes | Prediction | More>> | |||
| 1:1 ortholog | MID1 | 100524415 | A0A5G2R4L4 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | Mid1 | 54252 | P82458 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | mid1 | 100330952 | E7FAU0 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005881 | cytoplasmic microtubule |
| GO:0008017 | microtubule binding |
| GO:0051219 | phosphoprotein binding |
| GO:0042803 | protein homodimerization activity |
| GO:0031625 | ubiquitin protein ligase binding |
| GO:0008270 | zinc ion binding |
| GO:0032874 | positive regulation of stress-activated MAPK cascade |
| GO:0035372 | protein localization to microtubule |
| InterPro ID | InterPro Term |
|---|---|
| IPR001870 | B30.2/SPRY |
| IPR043136 | B30.2/SPRY_sf |
| IPR003649 | Bbox_C |
| IPR003879 | Butyrophylin_SPRY |
| IPR013320 | ConA-like_dom_sf |
| IPR017903 | COS_domain |
| IPR003961 | FN3_dom |
| IPR036116 | FN3_sf |
| IPR013783 | Ig-like_fold |
| IPR027727 | MID1 |
| IPR040859 | Midline-1_COS |
| IPR006574 | PRY |
| IPR003877 | SPRY_dom |
| IPR027370 | Znf-RING_LisH |
| IPR000315 | Znf_B-box |
| IPR001841 | Znf_RING |
| IPR013083 | Znf_RING/FYVE/PHD |
| IPR017907 | Znf_RING_CS |