| Tag | Content |
|---|---|
| Uniprot ID | H2PYE8; A0A2J8JNW0; |
| Entrez ID | 737621 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_016957044.1; XM_001146912.4; XM_016957041.1; |
| Ensembl protein ID | ENSPTRP00000000696 |
| Ensembl nucleotide ID | ENSPTRG00000000396 |
| Gene name | Keratinocyte differentiation factor 1 |
| Gene symbol | KDF1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MPRPGHPRPA SGPPRLGPWE RPTELCLETY DKPPQPPPSR RTRRPDPKDP GHHGPESITF 60 ISGSAEPAPE SPTCCLLWRP WVWEWCRAAF CFRRCRDCLQ RCGACVRGCS PCLSTEDSTE 120 GTAEANWAKE HNGVPPSPDR APPSRRDGQR LKSTMGSSFS YPDVKLKGIP VYPYPRATSP 180 APDADSCCKE PLADPPPMRH SLPSTLASSP RGSEEYYSFH ESDLDLPEMG SGSMSSREID 240 VLIFKKLTEL FSVHQIDELA KCTSDTVFLE KTSKISDLIS SITQDYHLDE QDAEGRLVRG 300 IIRISTRKSR ARPQTSEGRS TRAAAPTAAA PDSGHETMVG SGLSQDELTV QISQETTADA 360 IARKLRPYGV PGYPASHDSS FQGTDTDSSG APLLQVYC 398 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | KDF1 | 540019 | A5PJK4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 612121 | E2R9Y8 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 102179821 | A0A452FYZ0 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 100057007 | F7DZ26 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 126695 | Q8NAX2 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Kdf1 | 69073 | A2A9F4 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | KDF1 | 737621 | H2PYE8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 100511202 | F1STQ5 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | KDF1 | 100357150 | G1SQZ0 | Oryctolagus cuniculus | Prediction | More>> | ||
| 1:1 ortholog | kdf1a | 797923 | E7F2A2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005938 | cell cortex |
| GO:0030054 | cell junction |
| GO:0031252 | cell leading edge |
| GO:0072686 | mitotic spindle |
| GO:0005654 | nucleoplasm |
| GO:0048589 | developmental growth |
| GO:0061436 | establishment of skin barrier |
| GO:0003334 | keratinocyte development |
| GO:0060887 | limb epidermis development |
| GO:0016331 | morphogenesis of embryonic epithelium |
| GO:0010839 | negative regulation of keratinocyte proliferation |
| GO:2000647 | negative regulation of stem cell proliferation |
| GO:0045606 | positive regulation of epidermal cell differentiation |
| GO:0010482 | regulation of epidermal cell division |
| Keyword ID | Keyword Term |
|---|---|
| KW-1185 | Reference proteome |
| InterPro ID | InterPro Term |
|---|---|
| IPR028003 | KDF1 |
| Pfam ID | Pfam Term |
|---|---|
| PF15551 | DUF4656 |