Gene: KDF1

Basic information

Tag Content
Uniprot ID H2PYE8; A0A2J8JNW0;
Entrez ID 737621
Genbank protein ID
Genbank nucleotide ID XM_016957044.1; XM_001146912.4; XM_016957041.1;
Ensembl protein ID ENSPTRP00000000696
Ensembl nucleotide ID ENSPTRG00000000396
Gene name Keratinocyte differentiation factor 1
Gene symbol KDF1
Organism Pan troglodytes
NCBI taxa ID 9598
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MPRPGHPRPA SGPPRLGPWE RPTELCLETY DKPPQPPPSR RTRRPDPKDP GHHGPESITF 60
ISGSAEPAPE SPTCCLLWRP WVWEWCRAAF CFRRCRDCLQ RCGACVRGCS PCLSTEDSTE 120
GTAEANWAKE HNGVPPSPDR APPSRRDGQR LKSTMGSSFS YPDVKLKGIP VYPYPRATSP 180
APDADSCCKE PLADPPPMRH SLPSTLASSP RGSEEYYSFH ESDLDLPEMG SGSMSSREID 240
VLIFKKLTEL FSVHQIDELA KCTSDTVFLE KTSKISDLIS SITQDYHLDE QDAEGRLVRG 300
IIRISTRKSR ARPQTSEGRS TRAAAPTAAA PDSGHETMVG SGLSQDELTV QISQETTADA 360
IARKLRPYGV PGYPASHDSS FQGTDTDSSG APLLQVYC 398

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologKDF1540019A5PJK4Bos taurusPredictionMore>>
1:1 orthologKDF1612121E2R9Y8Canis lupus familiarisPredictionMore>>
1:1 orthologKDF1102179821A0A452FYZ0Capra hircusPredictionMore>>
1:1 orthologKDF1100057007F7DZ26Equus caballusPredictionMore>>
1:1 orthologKDF1126695Q8NAX2Homo sapiensPredictionMore>>
1:1 orthologKdf169073A2A9F4CPOMus musculusPublicationMore>>
1:1 orthologKDF1737621H2PYE8Pan troglodytesPredictionMore>>
1:1 orthologKDF1100511202F1STQ5Sus scrofaPredictionMore>>
1:1 orthologKDF1100357150G1SQZ0Oryctolagus cuniculusPredictionMore>>
1:1 orthologkdf1a797923E7F2A2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005938 cell cortex
GO:0030054 cell junction
GO:0031252 cell leading edge
GO:0072686 mitotic spindle
GO:0005654 nucleoplasm
GO:0048589 developmental growth
GO:0061436 establishment of skin barrier
GO:0003334 keratinocyte development
GO:0060887 limb epidermis development
GO:0016331 morphogenesis of embryonic epithelium
GO:0010839 negative regulation of keratinocyte proliferation
GO:2000647 negative regulation of stem cell proliferation
GO:0045606 positive regulation of epidermal cell differentiation
GO:0010482 regulation of epidermal cell division

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1185 Reference proteome

Interpro

InterPro ID InterPro Term
IPR028003 KDF1

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term
PF15551 DUF4656