| Tag | Content |
|---|---|
| Uniprot ID | H2R630 |
| Entrez ID | 459986 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_009444464.2; XM_016950591.1; XM_009444465.2; XM_516128.4; |
| Ensembl protein ID | ENSPTRP00000048691 |
| Ensembl nucleotide ID | ENSPTRG00000012991 |
| Gene name | Collagen type IV alpha 4 chain |
| Gene symbol | COL4A4 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MWSLHIVLMR CSFRLTKSLA TDPWSLTLIL FSVQYVYGSG KKYVGPCGGR DCSVCHCVPE 60 KGSRGPPGPP GPQGPIGPLG APGPIGLSGE KGMRGDHGPP GAAGDKGDKG STGVPGFPGL 120 DGIPGHPGPP GPRGKPGMSG HNGSRGDPGF PGGRGALGPG GPLGHPGEKG EKGNSVFILG 180 AVKGIQGDRG DPGLPGLPGS WGAGGPAGPT GYPGEPGLVG PPGQPGRPGL KGNPGVGVKG 240 QMGDPGEVGQ QGSPGPTLLV EPPDFRLYKG EKGIKGIPGM VGLPGPPGRK GESDIGAKGE 300 KGIPGFPGPR GDPGSYGSPG FPGLKGELGL VGDPGLFGLI GPKGDPGNRG HPGPPGVLVT 360 PPLPLKGPPG DPGFPGRYGE TGDVGPPGPP GLLGRPGEAC AGMIGPPGPQ GFPGLPGLPG 420 EAGIPGRPDS APGKPGKPGS PGLPGAPGLQ GLPGSSVIYC SVGNPGPQGI KGKVGPPGGR 480 GSKGEKGNEG LCACEPGPMG PPGPPGLPGR QGSKGDLGLP GWLGTKGDPG PPGAEGPPGL 540 PGKHGASGPP GNKGAKGDMV VSRVKGHKGE RGPDGPPGFP GQPGSHGRDG HAGEKGDPGP 600 PGDHEDATPG GKGFPGPLGP PGKAGPLGPP GLGFPGPPGQ RGHPGVPGHP GVRGPDGLKG 660 QKGDTISCNV TYPGRHGPPG FDGPPGPKGF PGPQGAPGLS GSDGHKGRPG TPGTAEIPGP 720 PGFRGDMGDP GFGGEKGSSP AGPPGPPGSP GVNGQKGIPG DPAFGHLGPP GKRGLSGVPG 780 IKGPRGDPGC PGAEGPAGIP GFPGLKGPKG REGHAGFPGV PGPPGHSCER GAPGIPGQPG 840 LPGYPGSPGA PGGKGQLGDV GPPGPAGMKG LPGLPGWPGA HGPPGLPGIP GPFGDDGLPG 900 PPGPKGPQGL PGFPGFPGER GKPGAEGCPG TKGEPGEKGM SGLPGDRGLR GAKGAIGPPG 960 DEGEMAIISQ KGTPGEPGPP GDDGFPGERG DKGTPGMQGR RGEPGRYGPP GFQRGEPGEK 1020 GQPGHPGPPG PPGSTGLRGF IGFPGLPGDQ GEPGSPGPPG FSGIDGARGP KGNKGDPASH 1080 FGPPGPKGEP GSPGCPGHFG ASGEQGLPGI QGPRGSPGRP GPPGSSGPPG CPGDHGMPGL 1140 RGQPGEMGDP GPRGLQGDPG IPGPPGIKGP SGSPGLNGLH GLKGQKGTKG ASGLHDVGPP 1200 GPVGIPGLKG ERGDPGSPGI SPPGPRGEKG PPGPPGSSGP PGPAGATGRA PKDIPDPGPP 1260 GDQGPPGPDG PRGAPGPPGL PGSVDLLRGE PGDCGLPGPP GPPGPPGPPG YKGFPGCDGK 1320 DGQKGPMGFP GPQGPHGFPG PPGEKGLPGP PGRKGPTGLP GPRGEPGPPA DVDDCPRIPG 1380 LPGAPGMRGP EGAMGLSGMR GPPGPGCKGE PGLDGRRGVD GVPGSPGPPG RKGDTGEDGY 1440 PGGPGPPGPI GDPGPKGFGP GYLGGFLLVL HSQTDQEPTC PLGMPRLWTG YSLLYLEGQE 1500 KAHNQDLGLA GSCLPVFSTL PFAYCNIHQV CHYAQRNDRS YWLASAAPLP MMPLSEEAIR 1560 PYVSRCAVCE APAQAVAVHS QDKSIPPCPQ TWRSLWIGYS FLMHTGAGDQ GGGQALMSPG 1620 SCLEDFRAAP FLECQGRQGT CHFFANKYSF WLTTVKADLQ FSSAPAPDTL KESQAQRQKI 1680 SRCQVCVKYS |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | COL4A4 | A0A452G3N1 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | COL4A4 | 1286 | P53420 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Col4a4 | 12829 | Q9QZR9 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | COL4A4 | 459986 | H2R630 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Col4a4 | A0A0G2K742 | Rattus norvegicus | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005587 | collagen type IV trimer |
| GO:0031012 | extracellular matrix |
| GO:0005615 | extracellular space |
| GO:0005201 | extracellular matrix structural constituent |
| GO:0038063 | collagen-activated tyrosine kinase receptor signaling pathway |
| GO:0030198 | extracellular matrix organization |
| GO:0032836 | glomerular basement membrane development |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51403 | NC1_IV |