Gene: STX18

Basic information

Tag Content
Uniprot ID J9P4H8
Entrez ID 609342
Genbank protein ID
Genbank nucleotide ID XM_845928.4
Ensembl protein ID ENSCAFP00000040457
Ensembl nucleotide ID ENSCAFG00000015700
Gene name Syntaxin 18
Gene symbol STX18
Organism Canis lupus familiaris
NCBI taxa ID 9615
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MAVDITLLFR ASVKTVKTRN KALGVAVGGG GVDGSRDELF RRSPRPKGDF SSRAREVISH 60
IGKLRDFLLE HRKDYINAYS HIMSEYGRMT DTERDQIDQD AQTFMRTCSE AIQQLRTQAH 120
KEIHSQQVKE HRSAVLDFIE DYLKRVCKLY SEQRAIRVKR VVDKKRLSKL EPEPHTKTRE 180
STSSEKVSQT PSQESEEKPV TEECPEKIPA ESQPELGTWG DGKGDDELSP EEIQMFEQEN 240
QRLIGEMNSL FDEVRQIEGR VVEISRLQEI FTEKVLQQEA EIDSIHQLVV GATENIKEGN 300
EDIREAIKNN AGFRVWVLFF LVMCSFSLLF LDWYDS 336

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSTX18609342J9P4H8Canis lupus familiarisPredictionMore>>
1:1 orthologSTX18A0A452FDT2Capra hircusPredictionMore>>
1:1 orthologSTX1853407Q9P2W9Homo sapiensPublicationMore>>
1:1 orthologStx1871116Q8VDS8Mus musculusPredictionMore>>
1:1 orthologSTX18741790K6Z7Y3Pan troglodytesPredictionMore>>
1:1 orthologSTX18A0A286ZVN3Sus scrofaPredictionMore>>
1:1 orthologStx18360953Q68FW4Rattus norvegicusPredictionMore>>
1:1 orthologstx18554130Q4VBI7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005783 endoplasmic reticulum
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
GO:0019904 protein domain specific binding
GO:0005484 SNAP receptor activity
GO:0090158 endoplasmic reticulum membrane organization
GO:0006886 intracellular protein transport
GO:1902953 positive regulation of ER to Golgi vesicle-mediated transport
GO:1902117 positive regulation of organelle assembly
GO:1903358 regulation of Golgi organization
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR019529 Syntaxin-18_N
IPR006012 Syntaxin/epimorphin_CS

PROSITE

PROSITE ID PROSITE Term
PS00914 SYNTAXIN

Pfam

Pfam ID Pfam Term
PF10496 Syntaxin-18_N