Gene: stx18

Basic information

Tag Content
Uniprot ID Q4VBI7
Entrez ID 554130
Genbank protein ID AAH95763.1
Genbank nucleotide ID NM_001024425.1
Ensembl protein ID ENSDARP00000051892
Ensembl nucleotide ID ENSDARG00000035763
Gene name Syntaxin-18
Gene symbol stx18
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description Syntaxin that may be involved in targeting and fusion of Golgi-derived retrograde transport vesicles with the ER.
Sequence
MAADITLLFK ASVKTVKTRN KALGLMETTG REEPGAQKRP RPRQRDSFSC KAREVISNIS 60
KLKDFLLQHR KDYVNAGSVM SSEVSRMTDS ERDQIDQDAQ IFMRTCAEAI SQLRSEMDKK 120
QVSMQVKDHR AAVLDLIDSY LKGVCKLYSE QRAVRVKRVV DKKRLSRLEP EQINTEKRQS 180
DGEENDKPVS DGNVDLWEEN RVEDDLSPEE IQMFEQENQR LVGEMNSLLD EVRQIEGKVV 240
EISRLQEIFS EKVLQQETEI DSIHQLVVGA TENVKEGNED IREAIKNNAG FRVWILFFLV 300
MCSFSLLFLD WYDS 314

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologSTX18609342J9P4H8Canis lupus familiarisPredictionMore>>
1:1 orthologSTX18A0A452FDT2Capra hircusPredictionMore>>
1:1 orthologSTX1853407Q9P2W9Homo sapiensPublicationMore>>
1:1 orthologStx1871116Q8VDS8Mus musculusPredictionMore>>
1:1 orthologSTX18741790K6Z7Y3Pan troglodytesPredictionMore>>
1:1 orthologSTX18A0A286ZVN3Sus scrofaPredictionMore>>
1:1 orthologStx18360953Q68FW4Rattus norvegicusPredictionMore>>
1:1 orthologstx18554130Q4VBI7Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005783 endoplasmic reticulum
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0031201 SNARE complex
GO:0005484 SNAP receptor activity
GO:0006886 intracellular protein transport
GO:0006890 retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0175 Coiled coil
KW-0256 Endoplasmic reticulum
KW-0931 ER-Golgi transport
KW-0472 Membrane
KW-0653 Protein transport
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix
KW-0813 Transport

Interpro

InterPro ID InterPro Term
IPR019529 Syntaxin-18_N
IPR006012 Syntaxin/epimorphin_CS

PROSITE

PROSITE ID PROSITE Term
PS00914 SYNTAXIN

Pfam

Pfam ID Pfam Term
PF10496 Syntaxin-18_N