| Tag | Content |
|---|---|
| Uniprot ID | K7DFT6; A0A2J8M2A1; |
| Entrez ID | 461438 |
| Genbank protein ID | JAA39974.1 |
| Genbank nucleotide ID | XM_009448143.2 |
| Ensembl protein ID | ENSPTRP00000082192 |
| Ensembl nucleotide ID | ENSPTRG00000016371 |
| Gene name | Homeobox protein |
| Gene symbol | PITX2 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | METNCRKLVS ACVQLEKDKS QQGKNEDVGA EDPSKKKRQR RQRTHFTSQQ LQELEATFQR 60 NRYPDMSTRE EIAVWTNLTE ARVRVWFKNR RAKWRKRERN QQAELCKNGF GPQFNGLMQP 120 YDDMYPGYSY NNWAAKGLTS ASLSTKSFPF FNSMNVNPLS SQSMFSPPNS ISSMSMSSSM 180 VPSAVTGVPG SSLNSLNNLN NLSSPSLNSA VPTPACPYAP PTPPYVYRDT CNSSLASLRL 240 KAKQHSSFGY ASVQNPASNL SACQYAVDRP V 271 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PITX2 | 506721 | A5D7J4 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PITX2 | 487902 | E2R5R2 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PITX2 | 102180740 | A0A452E417 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PITX2 | 5308 | Q99697 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pitx2 | 18741 | P97474 | CPO | E14.5 | Mus musculus | Publication | More>> |
| 1:1 ortholog | PITX2 | 461438 | K7DFT6 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PITX2 | A0A287AUF8 | Sus scrofa | Prediction | More>> | |||
| 1:1 ortholog | Pitx2 | 54284 | Q9R0W1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pitx2 | 30164 | Q9W5Z2 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005634 | nucleus |
| GO:0003700 | DNA-binding transcription factor activity |
| GO:0043565 | sequence-specific DNA binding |
| GO:0007275 | multicellular organism development |