Gene: Pak1ip1

Basic information

Tag Content
Uniprot ID Q32PZ0
Entrez ID 361232
Genbank protein ID EDL98226.1; AAI07923.1;
Genbank nucleotide ID NM_001037356.1
Ensembl protein ID ENSRNOP00000033583
Ensembl nucleotide ID ENSRNOG00000023799
Gene name PAK1-interacting protein 1
Gene symbol Pak1ip1
Organism Rattus norvegicus
NCBI taxa ID 10116
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MELVAGSYEQ VLFGFTVHRG PAKSGHRETW TPVADFTHHA HTASLSAVAA NNRYVVTGSK 60
DETIHIYDMK KKVEHGALVH HSGTVTCLKF YGSRHLISGA EDGLICVWDA KKWECLKSIK 120
AHRGHVTFLS IHPSGKLALS VGTDKTLRTW NLVEGRSAFI KNIKQNAHIV EWSPNGEKYV 180
VVVMNKVDVY HLDTASVSGT LTNGKRISAI TFLSDSVLAV AGDEEVVRFF DCDTLVCLCE 240
FKAHENRVKD MVSFEIPDHH VLVTASNDGF IKMWTLTQDK KAPPSLLCET NTGARLTCLG 300
VWLDRGTDEK ARLPPATEPC PDQPKTIEKE SADKIQEEAS APNAEKSDHT GGSQQPTKRN 360
SPAPAKKRKM ANVSEKKRKK KM 382

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologPAK1IP1102178321A0A452FB78Capra hircusPredictionMore>>
1:1 orthologPAK1IP155003Q9NWT1Homo sapiensPredictionMore>>
1:1 orthologPak1ip168083Q9DCE5CPOMus musculusPublicationMore>>
1:1 orthologPAK1IP1463143H2QSA5Pan troglodytesPredictionMore>>
1:1 orthologPAK1IP1K7GSP8Sus scrofaPredictionMore>>
1:1 orthologPAK1IP1100357229G1T599Oryctolagus cuniculusPredictionMore>>
1:1 orthologPak1ip1361232Q32PZ0Rattus norvegicusPredictionMore>>
1:1 orthologpak1ip1336470Q6TNS2Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005730 nucleolus
GO:0008283 cell population proliferation
GO:1901796 regulation of signal transduction by p53 class mediator
GO:0042273 ribosomal large subunit biogenesis
GO:0060021 roof of mouth development

Functional annotations

Keywords

Keyword ID Keyword Term
KW-1267 Proteomics identification
KW-1185 Reference proteome
KW-0853 WD repeat

Interpro

InterPro ID InterPro Term
IPR020472 G-protein_beta_WD-40_rep
IPR015943 WD40/YVTN_repeat-like_dom_sf
IPR001680 WD40_repeat
IPR019775 WD40_repeat_CS
IPR017986 WD40_repeat_dom
IPR036322 WD40_repeat_dom_sf

PROSITE

PROSITE ID PROSITE Term
PS00678 WD_REPEATS_1
PS50082 WD_REPEATS_2
PS50294 WD_REPEATS_REGION

Pfam

Pfam ID Pfam Term
PF00400 WD40