| Tag | Content |
|---|---|
| Uniprot ID | Q5U2R1 |
| Entrez ID | 365592 |
| Genbank protein ID | AAH85898.1 |
| Genbank nucleotide ID | NM_001014249.1 |
| Ensembl protein ID | ENSRNOP00000059060 |
| Ensembl nucleotide ID | ENSRNOG00000042962 |
| Gene name | Decaprenyl-diphosphate synthase subunit 2 |
| Gene symbol | Pdss2 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Supplies decaprenyl diphosphate, the precursor for the side chain of the isoprenoid quinones ubiquinone-10. |
| Sequence | MSLRQLLLRL SGYLGASGPP NRHWWYFRSL DTISSVGSWR GRSSRSPAHW NQVVSEAEKI 60 VGYPASFMSL RCLLSDELSN VAMQVRKLVG TQHPLLTTAR GFVHDSRHNL QLRGLVVLLI 120 SKAAGPSTRN SSSQNYDMVS GIYSCQRNLA EITELIHTAL LVHRGIVNLS ELQSSDGPLK 180 DMKFGNKIAV LSGDFLLANA CNGLALLQNT KVVELLASAL MDLVQGIYQE NSASTQGNPI 240 PDDIRISTWK EQTFLSHCAL LAKSCKAAME LAKHDAAVQD MAFQYGKHMA MSHKINSDLQ 300 PFIKDKASDS KTFNLNSAPV VLHQEFLGRD LWIKQIGEAQ EKGRLNYTKL RETIKAGKGV 360 TSAIDLCRYH GNKALEALES FPPSEARSAL ENIVFAVTRF S 401 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | PDSS2 | 521115 | A6QR05 | Bos taurus | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | 481950 | A0A5F4DM97 | Canis lupus familiaris | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | 102191138 | A0A452EPD3 | Capra hircus | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | 100072062 | A0A3Q2LJH9 | Equus caballus | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | 57107 | Q86YH6 | Homo sapiens | Prediction | More>> | ||
| 1:1 ortholog | Pdss2 | 71365 | Q33DR3 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | PDSS2 | 462912 | H2QTH8 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | 100312977 | D0G786 | Sus scrofa | Prediction | More>> | ||
| 1:1 ortholog | PDSS2 | A0A5F9DMW0 | Oryctolagus cuniculus | Prediction | More>> | |||
| 1:1 ortholog | Pdss2 | 365592 | Q5U2R1 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | pdss2 | B7ZD86 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005829 | cytosol |
| GO:0005739 | mitochondrion |
| GO:1990234 | transferase complex |
| GO:0046982 | protein heterodimerization activity |
| GO:0000010 | trans-hexaprenyltranstransferase activity |
| GO:0050347 | trans-octaprenyltranstransferase activity |
| GO:0008299 | isoprenoid biosynthetic process |
| GO:0050878 | regulation of body fluid levels |
| GO:0006744 | ubiquinone biosynthetic process |
| Pfam ID | Pfam Term |
|---|---|
| PF00348 | polyprenyl_synt |