| Tag | Content |
|---|---|
| Uniprot ID | Q5XIV0 |
| Entrez ID | 310721 |
| Genbank protein ID | AAH83570.1 |
| Genbank nucleotide ID | XM_006233038.3; NM_001014041.1; |
| Ensembl protein ID | ENSRNOP00000020401 |
| Ensembl nucleotide ID | ENSRNOG00000015222 |
| Gene name | Terminal nucleotidyltransferase 5C |
| Gene symbol | Tent5c |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | Nucleotidyltransferase that act as a non-canonical poly(A) RNA polymerase which enhances mRNA stability and gene expression. Mainly targets mRNAs encoding endoplasmic reticulum-targeted protein and may be involved in induction of cell death. |
| Sequence | MADEGSSTKD SESFSVLNWD QVSRLHEVLT EVVPIHGRGN FPTLEITLKD IVQTVRSRLE 60 EAGIKVQDVR LNGSAAGHVL VKDNGLGCKD LDLIFHVALP TEAEFQLVRD VVLCSLLNFL 120 PEGVNKLKIS PVTLKEAYVQ KLVKVCTDTD RWSLISLSNK NGRNVELKFV DSIRRQFEFS 180 VDSFQIILDS LLFFYDCSSN PVSEHFHPTV VGESMYGDFE EAFDHLQNRL IATKNPEEIR 240 GGGLLKYSNL LVRDFRPADQ EEIKTLERYM CSRFFIDFPD ILEQQRKLET YLQNHFADEE 300 RSKYDYLMIL RRVVNESTVC LMGHERRQTL NLISLLALRV LAEQNIIPSA TNVTCYYQPA 360 PYVSDGNFNN YYIAHPPVTY SQPYPTWLPC N 391 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.