| Tag | Content |
|---|---|
| Uniprot ID | Q8CH93 |
| Entrez ID | 282821 |
| Genbank protein ID | BAC43730.1 |
| Genbank nucleotide ID | NM_172323.1 |
| Ensembl protein ID | ENSRNOP00000014824 |
| Ensembl nucleotide ID | ENSRNOG00000010994 |
| Gene name | Hyaluronan synthase 1 |
| Gene symbol | Has1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MRQDMPKPSE AARCCSGLAR RVLTITFALL ILGLMTWAYA AGVPLASDPY GLLAFGLYGA 60 FLSAHLVAQS LFAYLEHRRV TVAARRAFAK GPLDAATARS VALTISAYQE DPTYLRQCLT 120 SARALLYPRT RLRVLMVVDG NRAEDLYMVD MFREVFADED PATYVWDGNY HQPWEPAEAA 180 GAVGEGAYRE VEAEDPGRLA VEALVRTRRC VCVAQRWGGK REVMYTAFKA LGDSVDYVQV 240 CDSDTRLDPM ALLELVRVLD EDPRVGAVGG DVRILNPLDS WVSFLSSLRY WVAFNVERAC 300 QSYFHCVSCI SGPLGLYRNN LLQQFLEAWY NQKFLGTHCT FGDDRHLTNR MLSMGYATKY 360 TSRSRCYSET PSSFLRWLSQ QTRWSKSYFR EWLYNALWWH RHHAWMTYEA VVSGLFPFFV 420 AATVLRLFYA GRPWALLWVL LCVQGVALAK AAFAAWLRGC LRMVLLSLYA PLYMCGLLPA 480 KFLALVTMNQ SGWGTSGRKK LAANYVPVLP LALWALLLLG GLIRSVAQEV RADWSGPSRA 540 AEAYHLAAGA SAYVAYWVIM LTIYWVGVRR LCRRRSGGYR VQV 583 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | HAS1 | A0A452FT40 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | HAS1 | M0R2V0 | Homo sapiens | Prediction | More>> | |||
| 1:1 ortholog | Has1 | 15116 | Q61647 | CPO | Mus musculus | Publication | More>> | |
| 1:1 ortholog | HAS1 | 468978 | A0A2I3TFP5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Has1 | 282821 | Q8CH93 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | has1 | 403130 | X1WCR3 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0005887 | integral component of plasma membrane |
| GO:0016020 | membrane |
| GO:0050501 | hyaluronan synthase activity |
| GO:0042802 | identical protein binding |
| GO:0036120 | cellular response to platelet-derived growth factor stimulus |
| GO:0044849 | estrous cycle |
| GO:0085029 | extracellular matrix assembly |
| GO:0045226 | extracellular polysaccharide biosynthetic process |
| GO:0030213 | hyaluronan biosynthetic process |
| GO:0010764 | negative regulation of fibroblast migration |