Gene: has1

Basic information

Tag Content
Uniprot ID X1WCR3
Entrez ID 403130
Genbank protein ID
Genbank nucleotide ID NM_001164030.1
Ensembl protein ID ENSDARP00000128010
Ensembl nucleotide ID ENSDARG00000042983
Gene name Hyaluronan synthase 1
Gene symbol has1
Organism Danio rerio
NCBI taxa ID 7955
Cleft type
Developmental stage
Data sources Homology search
Reference
Functional description
Sequence
MDLKPVLKKF VSLVRAFLTF LFALLVLGVM LWAYIDGFQI ATSPFGIISF GFYGVLLSLH 60
VLIQSFFAFV EHRRMNARRK PCSYTKTIGF TISAYQEDPA YLRECLQSVR ALQYPSELLR 120
IVMVVDGNSE DDRYMLEMFR EVFADQDPGC YIWQNNYHSW NPNGQDQGAA EGPDADYEVL 180
FEDPQRLEVE EIIRTKKCVC IMQKWGGKRE VMYTAFKALG SSVDFIQVCD SDTKLDPLAT 240
VELCKVLESN QKYGAVGGDV MILNLKDSYI SFMSSLRYWM AFNIERSCQS FFDCVSCISG 300
PLGLYRNDLL QQFLESWYNQ KFLGTHCTFG DDRHLTNRML SMGYATKYTA LSKCYTETPA 360
QFLRWLNQQT RWTKSYFREW LYNAMWWHKH HLWMTYESIV SGIFPFFVTA TIIKLFWTGT 420
LWDILWVLCS IQLIGLIKAG YACLLRQDIV MLFMSLYSAL YMTSLLPAKY FAIITMNKSS 480
WGTSGRRKMV GNYIPLAPLS VWAAILLGGL GYTIYREAKK SWLTEAKQEE IKFLIFGAVA 540
YVCYWLIMIC LYWIWFRRLF RKRSQTYTVN V 571

Abbreviation :
CLO : cleft lip only. CPO : cleft palate only. CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.

Protein disorder information

Orthologous information

Relation Gene symbol Entrez ID UniProt ID Cleft type Developmental stage Species Evidence Details
1:1 orthologHAS1A0A452FT40Capra hircusPredictionMore>>
1:1 orthologHAS1M0R2V0Homo sapiensPredictionMore>>
1:1 orthologHas115116Q61647CPOMus musculusPublicationMore>>
1:1 orthologHAS1468978A0A2I3TFP5Pan troglodytesPredictionMore>>
1:1 orthologHas1282821Q8CH93Rattus norvegicusPredictionMore>>
1:1 orthologhas1403130X1WCR3Danio rerioPredictionMore>>

Gene ontology

GO ID GO Term
GO:0005887 integral component of plasma membrane
GO:0016020 membrane
GO:0050501 hyaluronan synthase activity
GO:0085029 extracellular matrix assembly
GO:0045226 extracellular polysaccharide biosynthetic process
GO:0030213 hyaluronan biosynthetic process

Functional annotations

Keywords

Keyword ID Keyword Term
KW-0472 Membrane
KW-1185 Reference proteome
KW-0812 Transmembrane
KW-1133 Transmembrane helix

Interpro

InterPro ID InterPro Term
IPR028385 HAS1
IPR029044 Nucleotide-diphossugar_trans

PROSITE

PROSITE ID PROSITE Term

Pfam

Pfam ID Pfam Term