| Tag | Content |
|---|---|
| Uniprot ID | Q9CYB4 |
| Entrez ID | 13555 |
| Genbank protein ID | BAB30968.1 |
| Genbank nucleotide ID | NM_001291105.1; NM_007891.5; |
| Ensembl protein ID | ENSMUSP00000000894 |
| Ensembl nucleotide ID | ENSMUSG00000027490 |
| Gene name | Transcription factor E2F1 |
| Gene symbol | E2f1 |
| Organism | Mus musculus |
| NCBI taxa ID | 10090 |
| Cleft type | |
| Developmental stage | E12.5, E13.5, E14.5 |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MGKCFTQLQM VGLIFELMSA GLLQNLWLGS AHSCLLEVKR RLDLETDHQY LAGSSGPFRG 60 RGRHPGKGVK SPGEKSRYET SLNLTTKRFL ELLSRSADGV VDLNWAAEVL KVQKRRIYDI 120 TNVLEGIQLI AKKSKNHIQW LGSHTMVGIG KRLEGLTQDL QQLQESEQQL DHLMHICTTQ 180 LQLLSEDSDT QRLAYVTCQD LRSIADPAEQ MVIVIKAPPE TQLQAVDSSE TFQISLKSKQ 240 GPIDVFLCPE ESADGISPGK TSCQETSSGE DRTADSGPAG PPPSPPSTSP ALDPSQSLLG 300 LEQEAVLPRM GHLRVPMEED QLSPLVAADS LLEHVKEDFS GLLPGEFISL SPPHEALDYH 360 FGLEEGEGIR DLFDCDFGDL TPLDF 385 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | E2F1 | A0A452ESG5 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | E2F1 | 1869 | Q01094 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | E2f1 | 13555 | Q9CYB4 | E12.5, E13.5, E14.5 | Mus musculus | Prediction | More>> | |
| 1:1 ortholog | E2f1 | 399489 | O09139 | Rattus norvegicus | Prediction | More>> |
| Gene symbol | Significant Variants/SNPS | Methods | PubMed ID |
|---|---|---|---|
| E2F1 | rs2071054C>T | Genotyping | 25045080 |
| GO ID | GO Term | Evidence |
|---|
| GO ID | GO Term | Evidence |
|---|
| GO ID | GO Term | Evidence |
|---|
| Reactome ID | Reactome Term | Evidence |
|---|---|---|
| R-MMU-1640170 | Cell Cycle | IEA |
| R-MMU-453274 | Mitotic G2-G2/M phases | IEA |
| R-MMU-453279 | Mitotic G1 phase and G1/S transition | IEA |
| R-MMU-68689 | CDC6 association with the ORC:origin complex | IEA |
| R-MMU-68867 | Assembly of the pre-replicative complex | IEA |
| R-MMU-68911 | G2 Phase | IEA |
| R-MMU-69002 | DNA Replication Pre-Initiation | IEA |
| R-MMU-69231 | Cyclin D associated events in G1 | IEA |
| R-MMU-69236 | G1 Phase | IEA |
| R-MMU-69278 | Cell Cycle, Mitotic | IEA |
| R-MMU-69306 | DNA Replication | IEA |