| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 3156 |
Name | HMGCR |
Synonymous | LDLCQ3;3-hydroxy-3-methylglutaryl-CoA reductase;HMGCR;3-hydroxy-3-methylglutaryl-CoA reductase |
Definition | 3-hydroxy-3-methylglutaryl CoA reductase (NADPH)|3-hydroxy-3-methylglutaryl-Coenzyme A reductase|HMG-CoA reductase|hydroxymethylglutaryl-CoA reductase |
Position | 5q13.3-q14 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
There is no record for HMGCR | ||
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.G849V; chr5:74655898-74655898 |
lung | adenocarcinoma; carcinoma |
p.R630L; chr5:74652176-74652176 |
lung | adenocarcinoma; carcinoma |
p.K549R; chr5:74650963-74650963 |
lung | adenocarcinoma; carcinoma |
p.S520F; chr5:74650518-74650518 |
lung | adenocarcinoma; carcinoma |
p.G663C; chr5:74654482-74654482 |
lung | squamous_cell_carcinoma; carcinoma |
p.S290S; chr5:74646703-74646703 |
lung | adenocarcinoma; carcinoma |
p.G587W; chr5:74651226-74651226 |
lung | squamous_cell_carcinoma; carcinoma |
p.H270L; chr5:74646642-74646642 |
lung | adenocarcinoma; carcinoma |