| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5163 |
Name | PDK1 |
Synonymous | -;pyruvate dehydrogenase kinase, isozyme 1;PDK1;pyruvate dehydrogenase kinase, isozyme 1 |
Definition | PDH kinase 1|mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1|pyruvate dehydrogenase kinase, isoenzyme 1 |
Position | 2q31.1 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
There is no record for PDK1 | ||
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.C421Y; chr2:173460648-173460648 |
lung | adenocarcinoma; carcinoma |
p.P324S; chr2:173451030-173451030 |
lung | squamous_cell_carcinoma; carcinoma |
p.L352L; chr2:173451116-173451116 |
lung | adenocarcinoma; carcinoma |
p.E379Q; chr2:173457741-173457741 |
lung | adenocarcinoma; carcinoma |
p.?; chr2:173457662-173457662 |
lung | squamous_cell_carcinoma; carcinoma |
p.E290A; chr2:173435476-173435476 |
lung | adenocarcinoma; carcinoma |
p.I135V; chr2:173427012-173427012 |
lung | squamous_cell_carcinoma; carcinoma |
p.V303I; chr2:173435514-173435514 |
lung | adenocarcinoma; carcinoma |
p.K315M; chr2:173435551-173435551 |
lung | adenocarcinoma; carcinoma |
p.E227*; chr2:173429789-173429789 |
lung | adenocarcinoma; carcinoma |