| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 5163 |
Name | PDK1 |
Synonymous | -;pyruvate dehydrogenase kinase, isozyme 1;PDK1;pyruvate dehydrogenase kinase, isozyme 1 |
Definition | PDH kinase 1|mitochondrial pyruvate dehydrogenase, lipoamide, kinase isoenzyme 1|pyruvate dehydrogenase kinase, isoenzyme 1 |
Position | 2q31.1 |
Gene Type | protein-coding |
Gene Regulation: | ENCODE RegulomeDB Transcription Factors Post Transcriptional Modification From dbPTM Methylation Profile From DiseaseMeth database |
ENCODE RegulomeDB [Top] | |||
There is no record for PDK1 | |||
Transcription Factors [Top] |
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Regulation From TransFac database |
PDK1(h) --> pyruvate dehydrogenase (lipoamide) kinase isozyme 1, mitochondrial(h) (expression). | PDK1(h) --> pyruvate dehydrogenase (lipoamide) kinase isozyme 1, mitochondrial(h) (expression). | SGK-1(h) + ATP --pyruvate dehydrogenase (lipoamide) kinase isozyme 1, mitochondrial(h)--> SGK-1(h){p} + ADP (phosphorylation) |
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Post Transcriptional Modification [Top] | |||
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Location (AA) |
PTM type |
Literature |
Database |
25 | Phosphoserine | 12177059 | Phospho.ELM 6.0 | 396 | Phosphoserine | 12177059 | Phospho.ELM 6.0 | 393 | Phosphoserine | 12177059 | Phospho.ELM 6.0 |
|---|---|---|---|
Methylation Profile [Top] | ||
|
Chromosome |
Location |
Source |
|---|---|---|
chr2 |
Promoter: 173127525 - 173129525 | Agilent_014791 |
chr2 |
Promoter: 173127525 - 173129525 | GSE27584 |
chr2 |
Promoter: 173127525 - 173129525 | Agilent_014791_44K |