Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5743

Name

PTGS2

Synonymous

COX-2|COX2|GRIPGHS|PGG/HS|PGHS-2|PHS-2|hCox-2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase);PTGS2;prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase)

Definition

PGH synthase 2|PHS II|cyclooxygenase 2b|prostaglandin G/H synthase 2|prostaglandin H2 synthase 2

Position

1q25.2-q25.3

Gene Type

protein-coding

Gene Mutation:

GWAS results
PAH samples
Lung cancer

GWAS results   [Top]

There is no record for PTGS2

Lung cancer   [Top]

Mutation (Type; AA; Chr)

Site

Histology

p.?; chr1:186646963-186646963

lungadenocarcinoma; carcinoma

p.?; chr1:186644530-186644530

lungsmall_cell_carcinoma; carcinoma

p.?; chr1:186643895-186643895

lungsquamous_cell_carcinoma; carcinoma

p.R293L; chr1:186645691-186645691

lungsquamous_cell_carcinoma; carcinoma

p.S601*; chr1:186643498-186643498

lungadenocarcinoma; carcinoma

p.E539D; chr1:186643683-186643683

lungadenocarcinoma; carcinoma

p.R170T; chr1:186646911-186646911

lungadenocarcinoma; carcinoma

p.R499L; chr1:186643804-186643804

lungadenocarcinoma; carcinoma

p.W373C; chr1:186645168-186645168

lungadenocarcinoma; carcinoma

p.Y287H; chr1:186645710-186645710

lungadenocarcinoma; carcinoma

p.I544I; chr1:186643668-186643668

lungadenocarcinoma; carcinoma

p.C26C; chr1:186648545-186648545

lungadenocarcinoma; carcinoma

p.R499R; chr1:186643803-186643803

lungadenocarcinoma; carcinoma

p.I544I; chr1:186643668-186643668

lungadenocarcinoma; carcinoma

p.D111E; chr1:186647517-186647517

lungadenocarcinoma; carcinoma

p.C42C; chr1:186648497-186648497

lungsquamous_cell_carcinoma; carcinoma

p.W531C; chr1:186643707-186643707

lungadenocarcinoma; carcinoma


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