| General information | Literature | Expression | Regulation | Variant | Interaction |
|
Basic Information |
|
|---|---|
Gene ID | 7166 |
Name | TPH1 |
Synonymous | TPRH|TRPH;tryptophan hydroxylase 1;TPH1;tryptophan hydroxylase 1 |
Definition | L-tryptophan hydroxylase|indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase 1|tryptophan 5-monooxygenase 1|tryptophan hydroxylase (tryptophan 5-monooxygenase) |
Position | 11p15.3-p14 |
Gene Type | protein-coding |
Gene Mutation: | GWAS results PAH samples Lung cancer |
GWAS results [Top] | ||
There is no record for TPH1 | ||
Lung cancer [Top] | ||
|
Mutation (Type; AA; Chr) |
Site |
Histology |
|---|---|---|
p.G294C; chr11:18047172-18047172 |
lung | adenocarcinoma; carcinoma |
p.R17T; chr11:18062260-18062260 |
lung | squamous_cell_carcinoma; carcinoma |
p.R142S; chr11:18051105-18051105 |
lung | adenocarcinoma; carcinoma |
p.L435I; chr11:18042570-18042570 |
lung | adenocarcinoma; carcinoma |
p.F241L; chr11:18048117-18048117 |
lung | adenocarcinoma; carcinoma |
p.S260L; chr11:18048061-18048061 |
lung | adenocarcinoma; carcinoma |
p.C252R; chr11:18048086-18048086 |
lung | adenocarcinoma; carcinoma |
p.P92P; chr11:18057531-18057531 |
lung | adenocarcinoma; carcinoma |
p.H78D; chr11:18057575-18057575 |
lung | adenocarcinoma; carcinoma |
p.M124I; chr11:18054851-18054851 |
lung | adenocarcinoma; carcinoma |
p.P186Q; chr11:18050822-18050822 |
lung | squamous_cell_carcinoma; carcinoma |
p.?; chr11:18051058-18051058 |
lung | squamous_cell_carcinoma; carcinoma |
p.R142R; chr11:18051103-18051103 |
lung | adenocarcinoma; carcinoma |
p.V372I; chr11:18044391-18044391 |
lung | adenocarcinoma; carcinoma |
p.R406L; chr11:18042656-18042656 |
lung | adenocarcinoma; carcinoma |
p.W174F; chr11:18050857-18050858 |
lung | adenocarcinoma; carcinoma |