Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

7166

Name

TPH1

Synonymous

TPRH|TRPH;tryptophan hydroxylase 1;TPH1;tryptophan hydroxylase 1

Definition

L-tryptophan hydroxylase|indoleacetic acid-5-hydroxylase|tryptophan 5-hydroxylase 1|tryptophan 5-monooxygenase 1|tryptophan hydroxylase (tryptophan 5-monooxygenase)

Position

11p15.3-p14

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for TPH1

Transcription Factors   [Top]

Regulation From TransFac database

TPH1(h) --> tryptophan 5-hydroxylase 1 isoform-1(h) (expression).
TPH1(h) --> tryptophan 5-hydroxylase 1(h) (expression).
TPH1(h) --> tryptophan 5-hydroxylase 1 isoform-2(h) (expression).

Post Transcriptional Modification   [Top]

Location (AA)

PTM type

Literature

Database

58Phosphoserine (by PKA) (Potential).Swiss-Prot 53.0

Methylation Profile   [Top]

There is no record for TPH1



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