Pulmonary Arterial Hypertension KnowledgeBase (PAHKB)
PAHKB
Pulmonary Arterial Hypertension KnowledgeBase
General information | Literature | Expression | Regulation | Variant | Interaction

Basic Information

Gene ID

5592

Name

PRKG1

Synonymous

1|PKG|PRKG1B|PRKGR1B|cGK|cGK 1|cGK1|cGKI|cGKI-BETA|cGKI-alpha;protein kinase, cGMP-dependent, type I;PRKG1;protein kinase, cGMP-dependent, type I

Definition

cGMP-dependent protein kinase 1|protein kinase, cGMP-dependent, regulatory, type I, beta

Position

10q11.2

Gene Type

protein-coding

Gene Regulation:

ENCODE RegulomeDB
Transcription Factors
Post Transcriptional Modification From dbPTM
Methylation Profile From DiseaseMeth database

ENCODE RegulomeDB   [Top]

There is no record for PRKG1

Transcription Factors   [Top]

Regulation From TransFac database

PRKG1(h) --> cGKI-alpha(h) (expression).
cGKI-beta(h) + TFII-I(m) <==> cGKI-beta(h):TFII-I(m) (binding)
cGKI-beta(h) + TFII-I(h) <==> cGKI-beta(h):TFII-I(h) (binding)
PRKG1(h) --> cGKI-beta(h) (expression).
TFII-I(h) + ATP --cGKI-beta(h)--> TFII-I(h){p} + ADP (phosphorylation)
cGKI(h) --> HSL(h){pS} (increase of phosphorylation)
PRKG1(h) --> cGKI(h) (expression).

Post Transcriptional Modification   [Top]

There is no record for PRKG1

Methylation Profile   [Top]

Chromosome

Location

Source

chr10

Promoter: 52502799 - 52504799Agilent_014791

chr10

Promoter: 52502799 - 52504799GSE27584

chr10

Promoter: 52502799 - 52504799Agilent_014791_44K


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