Gene Page: RHOBTB2

Summary
GeneID  23221
Symbol  RHOBTB2
Synonyms  DBC2|KIAA0717
Description  Rho-related BTB domain containing 2
See related  HGNC:18756|MIM:607352|Ensembl:ENSG00000008853|HPRD:06300|
Locus tag  -
Gene type  protein-coding
Map location  8p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.031 
GSMA_IIAgenome scan meta-analysis (All samples)Psr: 0.03086 
GSMA_IIEgenome scan meta-analysis (European-ancestry samples)Psr: 0.00057 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PITPNM30.920.89
IQSEC20.920.87
SHANK10.910.89
OTUD7A0.910.87
SYNPO0.910.87
IQSEC10.900.90
SNPH0.900.93
C2orf550.900.80
IQSEC30.900.93
PACSIN10.900.85
Top 10 negatively co-expressed genes
RPL23A-0.50-0.57
C9orf46-0.50-0.53
EXOSC8-0.49-0.47
BCL7C-0.49-0.54
RPL32-0.47-0.50
RPS13P2-0.47-0.50
RPS18-0.47-0.50
RPS8-0.46-0.52
RPS6-0.46-0.52
DYNLT1-0.46-0.54
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000166nucleotide bindingIEA-
GO:0005515protein bindingIEA-
GO:0005525GTP bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007264small GTPase mediated signal transductionIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005622intracellularIEA-
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_UBIQUITIN_MEDIATED_PROTEOLYSIS 13898All SZGR genes in this pathway
REACTOME_SIGNALING_BY_RHO_GTPASES 11381All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_LIVE_DN 384220All SZGR genes in this pathway
ZHOU_INFLAMMATORY_RESPONSE_FIMA_DN 284156All SZGR genes in this pathway
DODD_NASOPHARYNGEAL_CARCINOMA_UP 1821933All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_DN 17811082All SZGR genes in this pathway
SCHAEFFER_PROSTATE_DEVELOPMENT_48HR_DN 428306All SZGR genes in this pathway
ZHANG_RESPONSE_TO_IKK_INHIBITOR_AND_TNF_DN 10364All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
SATO_SILENCED_BY_METHYLATION_IN_PANCREATIC_CANCER_1 419273All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_UP 566371All SZGR genes in this pathway
SHEDDEN_LUNG_CANCER_GOOD_SURVIVAL_A4 196124All SZGR genes in this pathway
KASLER_HDAC7_TARGETS_1_UP 194133All SZGR genes in this pathway
DELACROIX_RARG_BOUND_MEF 367231All SZGR genes in this pathway
ZWANG_EGF_PERSISTENTLY_UP 3224All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-129-5p8748811A,m8hsa-miR-129brainCUUUUUGCGGUCUGGGCUUGC
hsa-miR-129-5pCUUUUUGCGGUCUGGGCUUGCU
miR-370141114171Ahsa-miR-370brainGCCUGCUGGGGUGGAACCUGG
miR-410266726731Ahsa-miR-410AAUAUAACACAGAUGGCCUGU
miR-4508748801Ahsa-miR-450UUUUUGCGAUGUGUUCCUAAUA
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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