SZGR2

Summary ?

GeneID	3105
Symbol	HLA-A
Synonyms	Aw-33\|Aw-74\|HLAA
Description	major histocompatibility complex, class I, A
Reference	MIM:142800\|HGNC:HGNC:4931\|Ensembl:ENSG00000206503\|Ensembl:ENST00000376809\|Ensembl:ENST00000454091\|Ensembl:ENST00000456012\|HPRD:00826\|Vega:OTTHUMG00000130501
Gene type	protein-coding
Map location	6p21.3
Pascal p-value	1E-12
Sherlock p-value	0.382
Fetal beta	-1.353
eGene	Anterior cingulate cortex BA24 Caudate basal ganglia Cerebellar Hemisphere Cerebellum Cortex Frontal Cortex BA9 Hippocampus Hypothalamus Nucleus accumbens basal ganglia Putamen basal ganglia Myers' cis & trans Meta

Gene in Data Sources

Gene set name	Method of gene set	Description	Info
CV:GWAScat	Genome-wide Association Studies	This data set includes 560 SNPs associated with schizophrenia. A total of 486 genes were mapped to these SNPs within 50kb.
CV:GWASdb	Genome-wide Association Studies	GWASdb records for schizophrenia
CV:PGCnp	Genome-wide Association Study	GWAS
PMID:cooccur	High-throughput literature-search	Systematic search in PubMed for genes co-occurring with SCZ keywords. A total of 3027 genes were included.
GSMA_I	Genome scan meta-analysis	Psr: 0.033
Literature	High-throughput literature-search	Co-occurance with Schizophrenia keywords: schizophrenia,schizophrenic,schizophrenics,schizophrenias	Click to show details

Section I. Genetics and epigenetics annotation

eQTL annotation

SNP ID	Chromosome	Position	eGene	Gene Entrez ID	pvalue	qvalue	TSS distance	eQTL type
rs3117143	chr6	29031141	HLA-A	3105		0.05		cis
rs3129788	chr6	29057638	HLA-A	3105		0.01		cis
rs3116830	chr6	29167574	HLA-A	3105		7.295E-4		cis
rs3117425	chr6	29260430	HLA-A	3105		7.295E-4		cis
rs6934993	chr6	29337499	HLA-A	3105		0.02		cis
rs3749971	chr6	29342774	HLA-A	3105		0.15		cis
rs406511	chr6	29376384	HLA-A	3105		4.3E-6		cis
rs2523443	chr6	29415463	HLA-A	3105		2.268E-5		cis
rs2746149	chr6	29435354	HLA-A	3105		1.009E-4		cis
rs1233487	chr6	29468808	HLA-A	3105		0.09		cis
rs1233396	chr6	29546798	HLA-A	3105		2.386E-5		cis
rs926552	chr6	29548088	HLA-A	3105		2.349E-4		cis
rs1233367	chr6	29622219	HLA-A	3105		0.11		cis
rs29228	chr6	29623738	HLA-A	3105		3.633E-7		cis
rs3129063	chr6	29645612	HLA-A	3105		1.6E-7		cis
rs387642	chr6	29645633	HLA-A	3105		6.597E-5		cis
rs3117295	chr6	29653376	HLA-A	3105		6.553E-5		cis
rs3129047	chr6	29670572	HLA-A	3105		0.07		cis
rs3129046	chr6	29670651	HLA-A	3105		3.959E-4		cis
rs2523405	chr6	29695304	HLA-A	3105		0.08		cis
rs2523404	chr6	29695712	HLA-A	3105		0.03		cis
rs1611350	chr6	29698820	HLA-A	3105		0.08		cis
rs2523399	chr6	29700078	HLA-A	3105		6.869E-5		cis
rs1610601	chr6	29700182	HLA-A	3105		1.392E-4		cis
rs1737077	chr6	29725294	HLA-A	3105		3.877E-4		cis
rs1737031	chr6	29737480	HLA-A	3105		0		cis
rs885940	chr6	29739056	HLA-A	3105		0		cis
rs1610637	chr6	29739905	HLA-A	3105		3.48E-4		cis
rs1615962	chr6	29745725	HLA-A	3105		3.48E-4		cis
rs1633030	chr6	29745793	HLA-A	3105		0.01		cis
rs1614309	chr6	29745883	HLA-A	3105		0.01		cis
rs1633002	chr6	29765046	HLA-A	3105		3.48E-4		cis
rs1632973	chr6	29777170	HLA-A	3105		3.48E-4		cis
rs1736963	chr6	29777982	HLA-A	3105		3.48E-4		cis
rs2523408	chr6	29778108	HLA-A	3105		0.03		cis
rs1077433	chr6	29783063	HLA-A	3105		3.48E-4		cis
rs2253981	chr6	29805921	HLA-A	3105		3.764E-4		cis
rs2254071	chr6	29806061	HLA-A	3105		3.466E-4		cis
rs2734990	chr6	29812504	HLA-A	3105		0.03		cis
rs2523766	chr6	29812833	HLA-A	3105		0.03		cis
rs9258555	chr6	29813015	HLA-A	3105		0.2		cis
rs2517869	chr6	29819324	HLA-A	3105		8.778E-13		cis
rs2508052	chr6	29820001	HLA-A	3105		3.046E-13		cis
rs2734970	chr6	29834471	HLA-A	3105		2.985E-11		cis
rs1611631	chr6	29835653	HLA-A	3105		0.12		cis
rs2571410	chr6	29881463	HLA-A	3105		0.05		cis
rs389600	chr6	29896998	HLA-A	3105		6.993E-13		cis
rs1655927	chr6	29899492	HLA-A	3105		2.57E-13		cis
rs2975046	chr6	29915148	HLA-A	3105		9.951E-4		cis
rs2735096	chr6	29915750	HLA-A	3105		1.428E-10		cis
rs1632882	chr6	29916367	HLA-A	3105		2.403E-9		cis
rs417162	chr6	29916504	HLA-A	3105		6.134E-19		cis
rs1655900	chr6	29916617	HLA-A	3105		1.901E-13		cis
rs1632879	chr6	29917702	HLA-A	3105		0.06		cis
rs1655906	chr6	29918253	HLA-A	3105		0.06		cis
rs2508037	chr6	29918435	HLA-A	3105		1.123E-17		cis
rs3115637	chr6	29918452	HLA-A	3105		0.01		cis
rs3094674	chr6	29918537	HLA-A	3105		0.08		cis
rs2905760	chr6	29926460	HLA-A	3105		0.05		cis
rs2517672	chr6	29937261	HLA-A	3105		0		cis
rs2523969	chr6	29938776	HLA-A	3105		0		cis
rs4947244	chr6	29954363	HLA-A	3105		0.07		cis
rs2275855	chr6	29976788	HLA-A	3105		0.05		cis
rs9357092	chr6	29984251	HLA-A	3105		0.04		cis
rs3115631	chr6	29986323	HLA-A	3105		1.029E-5		cis
rs259934	chr6	30006875	HLA-A	3105		2.08E-4		cis
rs259940	chr6	30011933	HLA-A	3105		4.085E-4		cis
rs1264703	chr6	30065415	HLA-A	3105		4.488E-7		cis
rs1264702	chr6	30065574	HLA-A	3105		2.784E-7		cis
rs2517595	chr6	30084548	HLA-A	3105		0.04		cis
rs9261471	chr6	30105348	HLA-A	3105		0.05		cis
rs2857435	chr6	30106023	HLA-A	3105		0.08		cis
rs2857439	chr6	30106295	HLA-A	3105		0.03		cis
rs9261485	chr6	30108750	HLA-A	3105		0.05		cis
rs9261488	chr6	30109411	HLA-A	3105		0.06		cis
rs9261489	chr6	30109481	HLA-A	3105		0.04		cis
rs9261491	chr6	30109860	HLA-A	3105		0.01		cis
rs757262	chr6	30114954	HLA-A	3105		0.05		cis
rs1573298	chr6	30116159	HLA-A	3105		0.04		cis
rs9261518	chr6	30116984	HLA-A	3105		0.08		cis
rs9261519	chr6	30117100	HLA-A	3105		0.03		cis
rs2517618	chr6	30158126	HLA-A	3105		0.12		cis
rs2844775	chr6	30179421	HLA-A	3105		0.04		cis
rs2844780	chr6	30204525	HLA-A	3105		0.01		cis
rs261946	chr6	30271333	HLA-A	3105		0.08		cis
rs3132649	chr6	30321056	HLA-A	3105		2.593E-4		cis
rs3094061	chr6	30321188	HLA-A	3105		4.996E-4		cis
rs3130374	chr6	30321335	HLA-A	3105		4.996E-4		cis
rs3130351	chr6	30328191	HLA-A	3105		3.818E-6		cis
rs3130352	chr6	30328356	HLA-A	3105		1.417E-5		cis
rs3129818	chr6	30342965	HLA-A	3105		0		cis
rs3132625	chr6	30347719	HLA-A	3105		2.557E-6		cis
rs9404964	chr6	30347832	HLA-A	3105		0.07		cis
rs3094050	chr6	30358590	HLA-A	3105		1.047E-4		cis
rs3094703	chr6	30358956	HLA-A	3105		2.73E-5		cis
rs3094035	chr6	30363135	HLA-A	3105		9.62E-7		cis
rs3094034	chr6	30363350	HLA-A	3105		3.818E-6		cis
rs1034325	chr6	30368456	HLA-A	3105		0.04		cis
rs4713327	chr6	30383767	HLA-A	3105		0.01		cis
rs3094694	chr6	30451903	HLA-A	3105		0.01		cis
rs1075496	chr6	30658238	HLA-A	3105		0.04		cis
rs3132605	chr6	30739971	HLA-A	3105		0.03		cis
rs3131050	chr6	30760024	HLA-A	3105		0.03		cis
rs3131060	chr6	30763290	HLA-A	3105		0.05		cis
rs886424	chr6	30782001	HLA-A	3105		0.19		cis
rs3132581	chr6	30913457	HLA-A	3105		0.1		cis
rs3135309	chr6	28855804	HLA-A	3105		0.1		trans
rs3116830	chr6	29167574	HLA-A	3105		0.06		trans
rs3117425	chr6	29260430	HLA-A	3105		0.06		trans
rs406511	chr6	29376384	HLA-A	3105		7.367E-4		trans
rs2523443	chr6	29415463	HLA-A	3105		0		trans
rs2746149	chr6	29435354	HLA-A	3105		0.01		trans
rs1233396	chr6	29546798	HLA-A	3105		0		trans
rs926552	chr6	29548088	HLA-A	3105		0.02		trans
rs29228	chr6	29623738	HLA-A	3105		7.348E-5		trans
rs3129063	chr6	29645612	HLA-A	3105		3.478E-5		trans
rs387642	chr6	29645633	HLA-A	3105		0.01		trans
rs3117295	chr6	29653376	HLA-A	3105		0.01		trans
rs3129046	chr6	29670651	HLA-A	3105		0.03		trans
rs2523399	chr6	29700078	HLA-A	3105		0.01		trans
rs1610601	chr6	29700182	HLA-A	3105		0.01		trans
rs1737077	chr6	29725294	HLA-A	3105		0.03		trans
rs1737031	chr6	29737480	HLA-A	3105		0.13		trans
rs885940	chr6	29739056	HLA-A	3105		0.12		trans
rs1610637	chr6	29739905	HLA-A	3105		0.03		trans
rs1615962	chr6	29745725	HLA-A	3105		0.03		trans
rs1633002	chr6	29765046	HLA-A	3105		0.03		trans
rs1632973	chr6	29777170	HLA-A	3105		0.03		trans
rs1736963	chr6	29777982	HLA-A	3105		0.03		trans
rs9258466		0	HLA-A	3105		0.09		trans
rs1077433	chr6	29783063	HLA-A	3105		0.03		trans
rs2253981	chr6	29805921	HLA-A	3105		0.03		trans
rs2254071	chr6	29806061	HLA-A	3105		0.03		trans
rs407238		0	HLA-A	3105		9.808E-10		trans
rs2517869	chr6	29819324	HLA-A	3105		2.236E-10		trans
rs2508052	chr6	29820001	HLA-A	3105		7.32E-11		trans
snp_a-2077850		0	HLA-A	3105		3.003E-11		trans
rs2734970	chr6	29834471	HLA-A	3105		7.877E-9		trans
rs9258865		0	HLA-A	3105		5.751E-11		trans
rs389600	chr6	29896998	HLA-A	3105		1.785E-10		trans
rs1655927	chr6	29899492	HLA-A	3105		6.17E-11		trans
rs2975046	chr6	29915148	HLA-A	3105		0.07		trans
rs2735096	chr6	29915750	HLA-A	3105		3.639E-8		trans
rs1632882	chr6	29916367	HLA-A	3105		5.84E-7		trans
rs417162	chr6	29916504	HLA-A	3105		8.576E-17		trans
rs1655900	chr6	29916617	HLA-A	3105		4.326E-11		trans
rs2508037	chr6	29918435	HLA-A	3105		2.578E-15		trans
rs2517672	chr6	29937261	HLA-A	3105		0.19		trans
rs2523969	chr6	29938776	HLA-A	3105		0.16		trans
rs3115631	chr6	29986323	HLA-A	3105		0		trans
rs259934	chr6	30006875	HLA-A	3105		0.02		trans
rs259940	chr6	30011933	HLA-A	3105		0.03		trans
rs1264703	chr6	30065415	HLA-A	3105		8.913E-5		trans
rs1264702	chr6	30065574	HLA-A	3105		5.714E-5		trans
rs3132649	chr6	30321056	HLA-A	3105		0.02		trans
rs3094061	chr6	30321188	HLA-A	3105		0.04		trans
rs3130374	chr6	30321335	HLA-A	3105		0.04		trans
rs3130351	chr6	30328191	HLA-A	3105		6.609E-4		trans
rs3130352	chr6	30328356	HLA-A	3105		0		trans
rs3129818	chr6	30342965	HLA-A	3105		0.13		trans
rs3132625	chr6	30347719	HLA-A	3105		4.41E-4		trans
rs3094050	chr6	30358590	HLA-A	3105		0.01		trans
rs3094703	chr6	30358956	HLA-A	3105		0		trans
rs3094035	chr6	30363135	HLA-A	3105		1.813E-4		trans
rs3094034	chr6	30363350	HLA-A	3105		6.609E-4		trans
rs3130544	chr6	31058339	HLA-A	3105		0.19		trans
rs2844559	chr6	31340074	HLA-A	3105		0.19		trans
rs16910024	chr9	25988971	HLA-A	3105		0.11		trans
rs9259874	6	29898105	HLA-A	ENSG00000206503.7	1.598E-6	0.01	-10932	gtex_brain_ba24
rs9259896	6	29898559	HLA-A	ENSG00000206503.7	1.866E-6	0.01	-10478	gtex_brain_ba24
rs1611320	6	29902373	HLA-A	ENSG00000206503.7	1.774E-7	0.01	-6664	gtex_brain_ba24
rs1611329	6	29902875	HLA-A	ENSG00000206503.7	2.713E-7	0.01	-6162	gtex_brain_ba24
rs435760	6	29902949	HLA-A	ENSG00000206503.7	7.745E-7	0.01	-6088	gtex_brain_ba24
rs425482	6	29903217	HLA-A	ENSG00000206503.7	1.899E-7	0.01	-5820	gtex_brain_ba24
rs543075878	6	29903389	HLA-A	ENSG00000206503.7	4.76E-7	0.01	-5648	gtex_brain_ba24
rs567782341	6	29903577	HLA-A	ENSG00000206503.7	1.843E-7	0.01	-5460	gtex_brain_ba24
rs545567928	6	29903675	HLA-A	ENSG00000206503.7	1.706E-7	0.01	-5362	gtex_brain_ba24
rs9259976	6	29904131	HLA-A	ENSG00000206503.7	8.61E-7	0.01	-4906	gtex_brain_ba24
rs9259978	6	29904180	HLA-A	ENSG00000206503.7	8.265E-7	0.01	-4857	gtex_brain_ba24
rs9259981	6	29904357	HLA-A	ENSG00000206503.7	2.431E-7	0.01	-4680	gtex_brain_ba24
rs9259982	6	29904389	HLA-A	ENSG00000206503.7	8.86E-7	0.01	-4648	gtex_brain_ba24
rs2517736	6	29904505	HLA-A	ENSG00000206503.7	1.615E-6	0.01	-4532	gtex_brain_ba24
rs2524000	6	29904528	HLA-A	ENSG00000206503.7	1.624E-6	0.01	-4509	gtex_brain_ba24
rs400956	6	29905242	HLA-A	ENSG00000206503.7	1.536E-6	0.01	-3795	gtex_brain_ba24
rs9259998	6	29905360	HLA-A	ENSG00000206503.7	6.252E-7	0.01	-3677	gtex_brain_ba24
rs9260000	6	29905362	HLA-A	ENSG00000206503.7	3.21E-7	0.01	-3675	gtex_brain_ba24
rs433128	6	29905566	HLA-A	ENSG00000206503.7	1.157E-6	0.01	-3471	gtex_brain_ba24
rs2517731	6	29906049	HLA-A	ENSG00000206503.7	6.37E-7	0.01	-2988	gtex_brain_ba24
rs428081	6	29906512	HLA-A	ENSG00000206503.7	5.913E-7	0.01	-2525	gtex_brain_ba24
rs367077	6	29906564	HLA-A	ENSG00000206503.7	6.178E-7	0.01	-2473	gtex_brain_ba24
rs414215	6	29906772	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-2265	gtex_brain_ba24
rs9260029	6	29907243	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-1794	gtex_brain_ba24
rs9260032	6	29907286	HLA-A	ENSG00000206503.7	5.785E-7	0.01	-1751	gtex_brain_ba24
rs9260033	6	29907298	HLA-A	ENSG00000206503.7	5.785E-7	0.01	-1739	gtex_brain_ba24
rs9260036	6	29907494	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-1543	gtex_brain_ba24
rs9260038	6	29907544	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-1493	gtex_brain_ba24
rs387850	6	29907696	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-1341	gtex_brain_ba24
rs366907	6	29907755	HLA-A	ENSG00000206503.7	6.094E-7	0.01	-1282	gtex_brain_ba24
rs9260046	6	29908044	HLA-A	ENSG00000206503.7	6.141E-7	0.01	-993	gtex_brain_ba24
rs199654615	6	29908396	HLA-A	ENSG00000206503.7	2.989E-7	0.01	-641	gtex_brain_ba24
.	6	29908397	HLA-A	ENSG00000206503.7	2.623E-7	0.01	-640	gtex_brain_ba24
rs9260063	6	29908544	HLA-A	ENSG00000206503.7	5.127E-7	0.01	-493	gtex_brain_ba24
rs9260072	6	29908838	HLA-A	ENSG00000206503.7	5.599E-7	0.01	-199	gtex_brain_ba24
rs9260077	6	29908954	HLA-A	ENSG00000206503.7	5.139E-7	0.01	-83	gtex_brain_ba24
rs9260078	6	29909033	HLA-A	ENSG00000206503.7	9.779E-7	0.01	-4	gtex_brain_ba24
rs9260081	6	29909153	HLA-A	ENSG00000206503.7	5.203E-7	0.01	116	gtex_brain_ba24
rs9260087	6	29909376	HLA-A	ENSG00000206503.7	6.563E-7	0.01	339	gtex_brain_ba24
rs9260094	6	29909472	HLA-A	ENSG00000206503.7	5.621E-7	0.01	435	gtex_brain_ba24
rs9260096	6	29909510	HLA-A	ENSG00000206503.7	2.326E-7	0.01	473	gtex_brain_ba24
rs9260103	6	29909593	HLA-A	ENSG00000206503.7	6.227E-7	0.01	556	gtex_brain_ba24
rs9260104	6	29909616	HLA-A	ENSG00000206503.7	6.227E-7	0.01	579	gtex_brain_ba24
rs9260107	6	29909745	HLA-A	ENSG00000206503.7	6.317E-7	0.01	708	gtex_brain_ba24
rs9260111	6	29909916	HLA-A	ENSG00000206503.7	6.333E-7	0.01	879	gtex_brain_ba24
rs9260112	6	29909918	HLA-A	ENSG00000206503.7	6.333E-7	0.01	881	gtex_brain_ba24
rs9260115	6	29910027	HLA-A	ENSG00000206503.7	6.522E-7	0.01	990	gtex_brain_ba24
rs9260118	6	29910176	HLA-A	ENSG00000206503.7	6.522E-7	0.01	1139	gtex_brain_ba24
rs9260119	6	29910189	HLA-A	ENSG00000206503.7	6.522E-7	0.01	1152	gtex_brain_ba24
rs9260125	6	29910457	HLA-A	ENSG00000206503.7	1.22E-6	0.01	1420	gtex_brain_ba24
rs9260130	6	29910522	HLA-A	ENSG00000206503.7	8.139E-7	0.01	1485	gtex_brain_ba24
rs1136695	6	29911064	HLA-A	ENSG00000206503.7	6.253E-7	0.01	2027	gtex_brain_ba24
rs79222956	6	29911538	HLA-A	ENSG00000206503.7	6.569E-7	0.01	2501	gtex_brain_ba24
rs1136903	6	29912280	HLA-A	ENSG00000206503.7	1.101E-6	0.01	3243	gtex_brain_ba24
rs1141891	6	29912368	HLA-A	ENSG00000206503.7	5.892E-7	0.01	3331	gtex_brain_ba24
rs9260201	6	29912668	HLA-A	ENSG00000206503.7	1.01E-6	0.01	3631	gtex_brain_ba24
rs2975057	6	29913171	HLA-A	ENSG00000206503.7	6.548E-7	0.01	4134	gtex_brain_ba24
rs9260223	6	29913944	HLA-A	ENSG00000206503.7	6.513E-7	0.01	4907	gtex_brain_ba24
rs2523954	6	29914034	HLA-A	ENSG00000206503.7	7.162E-7	0.01	4997	gtex_brain_ba24
rs2571383	6	29914315	HLA-A	ENSG00000206503.7	6.522E-7	0.01	5278	gtex_brain_ba24
rs376646	6	29914377	HLA-A	ENSG00000206503.7	6.591E-7	0.01	5340	gtex_brain_ba24
rs396379	6	29914500	HLA-A	ENSG00000206503.7	6.522E-7	0.01	5463	gtex_brain_ba24
rs2524037	6	29914950	HLA-A	ENSG00000206503.7	6.511E-7	0.01	5913	gtex_brain_ba24
rs2517723	6	29915268	HLA-A	ENSG00000206503.7	2.132E-7	0.01	6231	gtex_brain_ba24
rs2517722	6	29915330	HLA-A	ENSG00000206503.7	2.132E-7	0.01	6293	gtex_brain_ba24
rs417162	6	29916505	HLA-A	ENSG00000206503.7	6.487E-7	0.01	7468	gtex_brain_ba24
rs9260316	6	29916914	HLA-A	ENSG00000206503.7	5.714E-7	0.01	7877	gtex_brain_ba24
rs2517716	6	29917260	HLA-A	ENSG00000206503.7	6.525E-7	0.01	8223	gtex_brain_ba24
rs2517713	6	29918099	HLA-A	ENSG00000206503.7	6.522E-7	0.01	9062	gtex_brain_ba24
rs2508037	6	29918436	HLA-A	ENSG00000206503.7	7.029E-7	0.01	9399	gtex_brain_ba24
rs2916806	6	29918684	HLA-A	ENSG00000206503.7	6.522E-7	0.01	9647	gtex_brain_ba24
rs2975043	6	29918734	HLA-A	ENSG00000206503.7	6.522E-7	0.01	9697	gtex_brain_ba24
rs2916807	6	29918770	HLA-A	ENSG00000206503.7	6.522E-7	0.01	9733	gtex_brain_ba24
rs9260403	6	29918861	HLA-A	ENSG00000206503.7	6.459E-7	0.01	9824	gtex_brain_ba24
rs9260408	6	29918917	HLA-A	ENSG00000206503.7	1.137E-6	0.01	9880	gtex_brain_ba24
rs9260413	6	29919010	HLA-A	ENSG00000206503.7	1.628E-7	0.01	9973	gtex_brain_ba24
rs9260424	6	29919098	HLA-A	ENSG00000206503.7	5.854E-7	0.01	10061	gtex_brain_ba24
rs547275509	6	29919141	HLA-A	ENSG00000206503.7	6.163E-7	0.01	10104	gtex_brain_ba24
rs2517709	6	29919421	HLA-A	ENSG00000206503.7	6.075E-7	0.01	10384	gtex_brain_ba24
rs2517706	6	29919659	HLA-A	ENSG00000206503.7	6.693E-7	0.01	10622	gtex_brain_ba24
rs9260463	6	29919862	HLA-A	ENSG00000206503.7	6.453E-7	0.01	10825	gtex_brain_ba24
rs9260464	6	29919864	HLA-A	ENSG00000206503.7	6.453E-7	0.01	10827	gtex_brain_ba24
rs9260483	6	29920238	HLA-A	ENSG00000206503.7	6.48E-7	0.01	11201	gtex_brain_ba24
rs9260484	6	29920253	HLA-A	ENSG00000206503.7	6.48E-7	0.01	11216	gtex_brain_ba24
rs9260486	6	29920281	HLA-A	ENSG00000206503.7	6.396E-7	0.01	11244	gtex_brain_ba24
rs2975042	6	29920536	HLA-A	ENSG00000206503.7	6.522E-7	0.01	11499	gtex_brain_ba24
rs2916809	6	29920549	HLA-A	ENSG00000206503.7	6.522E-7	0.01	11512	gtex_brain_ba24
rs9260599	6	29922653	HLA-A	ENSG00000206503.7	6.522E-7	0.01	13616	gtex_brain_ba24
rs2571390	6	29923554	HLA-A	ENSG00000206503.7	1.443E-6	0.01	14517	gtex_brain_ba24
rs2844810	6	29923580	HLA-A	ENSG00000206503.7	6.652E-7	0.01	14543	gtex_brain_ba24
rs1632984	6	29773392	HLA-A	ENSG00000206503.7	1.676E-6	0	-135645	gtex_brain_putamen_basal
rs1632972	6	29777346	HLA-A	ENSG00000206503.7	1.676E-6	0	-131691	gtex_brain_putamen_basal
rs1736965	6	29777443	HLA-A	ENSG00000206503.7	1.676E-6	0	-131594	gtex_brain_putamen_basal
rs1632971	6	29777911	HLA-A	ENSG00000206503.7	1.676E-6	0	-131126	gtex_brain_putamen_basal
rs1736962	6	29778613	HLA-A	ENSG00000206503.7	1.676E-6	0	-130424	gtex_brain_putamen_basal
rs1736952	6	29785653	HLA-A	ENSG00000206503.7	1.676E-6	0	-123384	gtex_brain_putamen_basal
rs2743931	6	29787072	HLA-A	ENSG00000206503.7	1.676E-6	0	-121965	gtex_brain_putamen_basal
rs1633017	6	29788770	HLA-A	ENSG00000206503.7	1.676E-6	0	-120267	gtex_brain_putamen_basal
rs1233334	6	29794897	HLA-A	ENSG00000206503.7	3.001E-6	0	-114140	gtex_brain_putamen_basal
rs56388903	6	29795720	HLA-A	ENSG00000206503.7	2.117E-6	0	-113317	gtex_brain_putamen_basal
rs1707	6	29798610	HLA-A	ENSG00000206503.7	2.406E-6	0	-110427	gtex_brain_putamen_basal
rs1233330	6	29799103	HLA-A	ENSG00000206503.7	2.117E-6	0	-109934	gtex_brain_putamen_basal
rs394146	6	29799235	HLA-A	ENSG00000206503.7	1.738E-6	0	-109802	gtex_brain_putamen_basal
rs1234836	6	29801035	HLA-A	ENSG00000206503.7	1.676E-6	0	-108002	gtex_brain_putamen_basal
rs1233326	6	29804071	HLA-A	ENSG00000206503.7	1.676E-6	0	-104966	gtex_brain_putamen_basal
rs1233324	6	29806107	HLA-A	ENSG00000206503.7	1.676E-6	0	-102930	gtex_brain_putamen_basal
rs3094644	6	29812578	HLA-A	ENSG00000206503.7	1.898E-6	0	-96459	gtex_brain_putamen_basal
rs3132727	6	29813363	HLA-A	ENSG00000206503.7	1.676E-6	0	-95674	gtex_brain_putamen_basal
rs3128912	6	29815637	HLA-A	ENSG00000206503.7	1.676E-6	0	-93400	gtex_brain_putamen_basal
rs3115629	6	29815713	HLA-A	ENSG00000206503.7	1.676E-6	0	-93324	gtex_brain_putamen_basal
rs3128911	6	29818030	HLA-A	ENSG00000206503.7	1.676E-6	0	-91007	gtex_brain_putamen_basal
rs3128908	6	29824267	HLA-A	ENSG00000206503.7	2.261E-6	0	-84770	gtex_brain_putamen_basal
rs9258693	6	29824534	HLA-A	ENSG00000206503.7	1.959E-6	0	-84503	gtex_brain_putamen_basal
rs9258694	6	29824537	HLA-A	ENSG00000206503.7	1.959E-6	0	-84500	gtex_brain_putamen_basal
rs3128907	6	29824994	HLA-A	ENSG00000206503.7	1.676E-6	0	-84043	gtex_brain_putamen_basal
rs3094172	6	29828019	HLA-A	ENSG00000206503.7	1.676E-6	0	-81018	gtex_brain_putamen_basal
rs3094170	6	29829265	HLA-A	ENSG00000206503.7	1.676E-6	0	-79772	gtex_brain_putamen_basal
rs3094656	6	29830751	HLA-A	ENSG00000206503.7	2.117E-6	0	-78286	gtex_brain_putamen_basal
rs3128904	6	29831466	HLA-A	ENSG00000206503.7	2.117E-6	0	-77571	gtex_brain_putamen_basal
rs3094168	6	29831577	HLA-A	ENSG00000206503.7	1.676E-6	0	-77460	gtex_brain_putamen_basal
rs3128902	6	29832514	HLA-A	ENSG00000206503.7	1.676E-6	0	-76523	gtex_brain_putamen_basal
rs3128901	6	29832907	HLA-A	ENSG00000206503.7	1.676E-6	0	-76130	gtex_brain_putamen_basal
rs2734976	6	29832958	HLA-A	ENSG00000206503.7	3.03E-6	0	-76079	gtex_brain_putamen_basal
rs3094166	6	29833102	HLA-A	ENSG00000206503.7	1.676E-6	0	-75935	gtex_brain_putamen_basal
rs9258859	6	29836090	HLA-A	ENSG00000206503.7	1.682E-6	0	-72947	gtex_brain_putamen_basal
rs3094157	6	29836239	HLA-A	ENSG00000206503.7	1.676E-6	0	-72798	gtex_brain_putamen_basal
rs3128888	6	29841356	HLA-A	ENSG00000206503.7	1.676E-6	0	-67681	gtex_brain_putamen_basal
rs1611581	6	29850827	HLA-A	ENSG00000206503.7	5.433E-7	0	-58210	gtex_brain_putamen_basal
rs3115612	6	29851443	HLA-A	ENSG00000206503.7	3.165E-6	0	-57594	gtex_brain_putamen_basal
rs3094645	6	29853936	HLA-A	ENSG00000206503.7	1.991E-6	0	-55101	gtex_brain_putamen_basal
rs9259329	6	29861134	HLA-A	ENSG00000206503.7	1.101E-6	0	-47903	gtex_brain_putamen_basal
rs1611440	6	29880429	HLA-A	ENSG00000206503.7	1.72E-6	0	-28608	gtex_brain_putamen_basal
rs6926454	6	29897872	HLA-A	ENSG00000206503.7	2.547E-6	0	-11165	gtex_brain_putamen_basal
rs9259871	6	29897974	HLA-A	ENSG00000206503.7	2.462E-6	0	-11063	gtex_brain_putamen_basal
rs9259874	6	29898105	HLA-A	ENSG00000206503.7	2.78E-6	0	-10932	gtex_brain_putamen_basal
rs9259896	6	29898559	HLA-A	ENSG00000206503.7	2.697E-6	0	-10478	gtex_brain_putamen_basal
rs2517741	6	29898806	HLA-A	ENSG00000206503.7	2.372E-6	0	-10231	gtex_brain_putamen_basal
rs2517740	6	29898821	HLA-A	ENSG00000206503.7	2.369E-6	0	-10216	gtex_brain_putamen_basal
rs1611320	6	29902373	HLA-A	ENSG00000206503.7	1.318E-7	0	-6664	gtex_brain_putamen_basal
rs1611329	6	29902875	HLA-A	ENSG00000206503.7	3.647E-7	0	-6162	gtex_brain_putamen_basal
rs435760	6	29902949	HLA-A	ENSG00000206503.7	1.197E-7	0	-6088	gtex_brain_putamen_basal
rs543075878	6	29903389	HLA-A	ENSG00000206503.7	1.191E-6	0	-5648	gtex_brain_putamen_basal
rs567782341	6	29903577	HLA-A	ENSG00000206503.7	3.415E-7	0	-5460	gtex_brain_putamen_basal
rs545567928	6	29903675	HLA-A	ENSG00000206503.7	2.114E-7	0	-5362	gtex_brain_putamen_basal
rs9259976	6	29904131	HLA-A	ENSG00000206503.7	6.655E-8	0	-4906	gtex_brain_putamen_basal
rs9259978	6	29904180	HLA-A	ENSG00000206503.7	7.484E-8	0	-4857	gtex_brain_putamen_basal
rs9259981	6	29904357	HLA-A	ENSG00000206503.7	1.424E-7	0	-4680	gtex_brain_putamen_basal
rs9259982	6	29904389	HLA-A	ENSG00000206503.7	6.564E-8	0	-4648	gtex_brain_putamen_basal
rs2517736	6	29904505	HLA-A	ENSG00000206503.7	3.324E-8	0	-4532	gtex_brain_putamen_basal
rs2524000	6	29904528	HLA-A	ENSG00000206503.7	2.957E-8	0	-4509	gtex_brain_putamen_basal
rs2523998	6	29904865	HLA-A	ENSG00000206503.7	2.634E-6	0	-4172	gtex_brain_putamen_basal
rs2916815	6	29905015	HLA-A	ENSG00000206503.7	2.325E-6	0	-4022	gtex_brain_putamen_basal
rs9259991	6	29905101	HLA-A	ENSG00000206503.7	4.334E-8	0	-3936	gtex_brain_putamen_basal
rs9259992	6	29905121	HLA-A	ENSG00000206503.7	2.035E-8	0	-3916	gtex_brain_putamen_basal
rs400956	6	29905242	HLA-A	ENSG00000206503.7	1.014E-8	0	-3795	gtex_brain_putamen_basal
rs9259998	6	29905360	HLA-A	ENSG00000206503.7	6.227E-8	0	-3677	gtex_brain_putamen_basal
rs9260000	6	29905362	HLA-A	ENSG00000206503.7	1.41E-7	0	-3675	gtex_brain_putamen_basal
rs201291609	6	29905512	HLA-A	ENSG00000206503.7	7.75E-8	0	-3525	gtex_brain_putamen_basal
rs433128	6	29905566	HLA-A	ENSG00000206503.7	3.932E-8	0	-3471	gtex_brain_putamen_basal
rs9260010	6	29905804	HLA-A	ENSG00000206503.7	1.514E-7	0	-3233	gtex_brain_putamen_basal
rs2517731	6	29906049	HLA-A	ENSG00000206503.7	1.712E-8	0	-2988	gtex_brain_putamen_basal
rs428081	6	29906512	HLA-A	ENSG00000206503.7	1.864E-8	0	-2525	gtex_brain_putamen_basal
rs367077	6	29906564	HLA-A	ENSG00000206503.7	1.044E-8	0	-2473	gtex_brain_putamen_basal
rs2860580	6	29906691	HLA-A	ENSG00000206503.7	5.081E-7	0	-2346	gtex_brain_putamen_basal
rs414215	6	29906772	HLA-A	ENSG00000206503.7	1.768E-8	0	-2265	gtex_brain_putamen_basal
rs9260029	6	29907243	HLA-A	ENSG00000206503.7	2.083E-8	0	-1794	gtex_brain_putamen_basal
rs9260032	6	29907286	HLA-A	ENSG00000206503.7	3.668E-8	0	-1751	gtex_brain_putamen_basal
rs9260033	6	29907298	HLA-A	ENSG00000206503.7	3.689E-8	0	-1739	gtex_brain_putamen_basal
rs9260036	6	29907494	HLA-A	ENSG00000206503.7	2.312E-8	0	-1543	gtex_brain_putamen_basal
rs9260038	6	29907544	HLA-A	ENSG00000206503.7	2.356E-8	0	-1493	gtex_brain_putamen_basal
rs387850	6	29907696	HLA-A	ENSG00000206503.7	2.515E-8	0	-1341	gtex_brain_putamen_basal
rs366907	6	29907755	HLA-A	ENSG00000206503.7	2.508E-8	0	-1282	gtex_brain_putamen_basal
rs1614003	6	29907996	HLA-A	ENSG00000206503.7	3.874E-7	0	-1041	gtex_brain_putamen_basal
rs9260046	6	29908044	HLA-A	ENSG00000206503.7	2.93E-8	0	-993	gtex_brain_putamen_basal
rs199654615	6	29908396	HLA-A	ENSG00000206503.7	5.475E-8	0	-641	gtex_brain_putamen_basal
.	6	29908397	HLA-A	ENSG00000206503.7	7.614E-8	0	-640	gtex_brain_putamen_basal
rs9260063	6	29908544	HLA-A	ENSG00000206503.7	2.862E-8	0	-493	gtex_brain_putamen_basal
rs9260072	6	29908838	HLA-A	ENSG00000206503.7	3.807E-8	0	-199	gtex_brain_putamen_basal
rs9260077	6	29908954	HLA-A	ENSG00000206503.7	2.377E-8	0	-83	gtex_brain_putamen_basal
rs9260078	6	29909033	HLA-A	ENSG00000206503.7	1.895E-6	0	-4	gtex_brain_putamen_basal
rs9260081	6	29909153	HLA-A	ENSG00000206503.7	2.691E-8	0	116	gtex_brain_putamen_basal
rs1632889	6	29909181	HLA-A	ENSG00000206503.7	3.226E-7	0	144	gtex_brain_putamen_basal
rs1655919	6	29909197	HLA-A	ENSG00000206503.7	1.677E-6	0	160	gtex_brain_putamen_basal
rs9260087	6	29909376	HLA-A	ENSG00000206503.7	1.947E-8	0	339	gtex_brain_putamen_basal
rs9260094	6	29909472	HLA-A	ENSG00000206503.7	1.241E-8	0	435	gtex_brain_putamen_basal
rs9260096	6	29909510	HLA-A	ENSG00000206503.7	4.713E-8	0	473	gtex_brain_putamen_basal
rs9260098	6	29909523	HLA-A	ENSG00000206503.7	1.496E-6	0	486	gtex_brain_putamen_basal
rs9260103	6	29909593	HLA-A	ENSG00000206503.7	5.132E-8	0	556	gtex_brain_putamen_basal
rs9260104	6	29909616	HLA-A	ENSG00000206503.7	5.184E-8	0	579	gtex_brain_putamen_basal
rs9260107	6	29909745	HLA-A	ENSG00000206503.7	4.966E-8	0	708	gtex_brain_putamen_basal
rs9260111	6	29909916	HLA-A	ENSG00000206503.7	7.552E-8	0	879	gtex_brain_putamen_basal
rs9260112	6	29909918	HLA-A	ENSG00000206503.7	7.566E-8	0	881	gtex_brain_putamen_basal
rs9260114	6	29909988	HLA-A	ENSG00000206503.7	1.656E-7	0	951	gtex_brain_putamen_basal
rs9260115	6	29910027	HLA-A	ENSG00000206503.7	3.998E-8	0	990	gtex_brain_putamen_basal
rs3132688	6	29910083	HLA-A	ENSG00000206503.7	1.755E-6	0	1046	gtex_brain_putamen_basal
rs9260118	6	29910176	HLA-A	ENSG00000206503.7	4.251E-8	0	1139	gtex_brain_putamen_basal
rs9260119	6	29910189	HLA-A	ENSG00000206503.7	4.251E-8	0	1152	gtex_brain_putamen_basal
rs2916801	6	29910286	HLA-A	ENSG00000206503.7	3.545E-7	0	1249	gtex_brain_putamen_basal
rs9260125	6	29910457	HLA-A	ENSG00000206503.7	2.319E-7	0	1420	gtex_brain_putamen_basal
rs9260127	6	29910478	HLA-A	ENSG00000206503.7	9.043E-7	0	1441	gtex_brain_putamen_basal
rs9260129	6	29910508	HLA-A	ENSG00000206503.7	1.238E-7	0	1471	gtex_brain_putamen_basal
rs9260130	6	29910522	HLA-A	ENSG00000206503.7	5.66E-8	0	1485	gtex_brain_putamen_basal
rs1136695	6	29911064	HLA-A	ENSG00000206503.7	5.282E-8	0	2027	gtex_brain_putamen_basal
rs1059542	6	29911256	HLA-A	ENSG00000206503.7	1.502E-6	0	2219	gtex_brain_putamen_basal
rs67054159	6	29911457	HLA-A	ENSG00000206503.7	1.733E-6	0	2420	gtex_brain_putamen_basal
rs79222956	6	29911538	HLA-A	ENSG00000206503.7	4.12E-8	0	2501	gtex_brain_putamen_basal
rs1136903	6	29912280	HLA-A	ENSG00000206503.7	3.82E-8	0	3243	gtex_brain_putamen_basal
rs1141891	6	29912368	HLA-A	ENSG00000206503.7	3.34E-8	0	3331	gtex_brain_putamen_basal
rs1655895	6	29912517	HLA-A	ENSG00000206503.7	1.777E-6	0	3480	gtex_brain_putamen_basal
rs9260201	6	29912668	HLA-A	ENSG00000206503.7	4.852E-8	0	3631	gtex_brain_putamen_basal
rs2571381	6	29912830	HLA-A	ENSG00000206503.7	3.454E-7	0	3793	gtex_brain_putamen_basal
rs1137296	6	29912852	HLA-A	ENSG00000206503.7	2.198E-8	0	3815	gtex_brain_putamen_basal
rs14288	6	29913042	HLA-A	ENSG00000206503.7	2.198E-6	0	4005	gtex_brain_putamen_basal
rs9260205	6	29913074	HLA-A	ENSG00000206503.7	4.652E-7	0	4037	gtex_brain_putamen_basal
rs41546815	6	29913078	HLA-A	ENSG00000206503.7	4.652E-7	0	4041	gtex_brain_putamen_basal
rs2975057	6	29913171	HLA-A	ENSG00000206503.7	4.182E-8	0	4134	gtex_brain_putamen_basal
rs2499	6	29913542	HLA-A	ENSG00000206503.7	1.676E-6	0	4505	gtex_brain_putamen_basal
rs13488	6	29913638	HLA-A	ENSG00000206503.7	3.332E-7	0	4601	gtex_brain_putamen_basal
rs2248006	6	29913672	HLA-A	ENSG00000206503.7	3.476E-7	0	4635	gtex_brain_putamen_basal
rs2571382	6	29913727	HLA-A	ENSG00000206503.7	3.315E-7	0	4690	gtex_brain_putamen_basal
rs9260223	6	29913944	HLA-A	ENSG00000206503.7	4.232E-8	0	4907	gtex_brain_putamen_basal
rs2523954	6	29914034	HLA-A	ENSG00000206503.7	4.014E-8	0	4997	gtex_brain_putamen_basal
rs1616549	6	29914270	HLA-A	ENSG00000206503.7	1.676E-6	0	5233	gtex_brain_putamen_basal
rs2571383	6	29914315	HLA-A	ENSG00000206503.7	4.251E-8	0	5278	gtex_brain_putamen_basal
rs376646	6	29914377	HLA-A	ENSG00000206503.7	4.196E-8	0	5340	gtex_brain_putamen_basal
rs396379	6	29914500	HLA-A	ENSG00000206503.7	4.251E-8	0	5463	gtex_brain_putamen_basal
rs2524037	6	29914950	HLA-A	ENSG00000206503.7	4.291E-8	0	5913	gtex_brain_putamen_basal
rs2248162	6	29915061	HLA-A	ENSG00000206503.7	7.914E-8	0	6024	gtex_brain_putamen_basal
rs2571386	6	29915122	HLA-A	ENSG00000206503.7	1.676E-6	0	6085	gtex_brain_putamen_basal
rs2517723	6	29915268	HLA-A	ENSG00000206503.7	3.514E-8	0	6231	gtex_brain_putamen_basal
rs2517722	6	29915330	HLA-A	ENSG00000206503.7	3.525E-8	0	6293	gtex_brain_putamen_basal
rs417162	6	29916505	HLA-A	ENSG00000206503.7	4.343E-8	0	7468	gtex_brain_putamen_basal
rs1655902	6	29916855	HLA-A	ENSG00000206503.7	7.023E-7	0	7818	gtex_brain_putamen_basal
rs9260316	6	29916914	HLA-A	ENSG00000206503.7	6.053E-8	0	7877	gtex_brain_putamen_basal
rs1655903	6	29917005	HLA-A	ENSG00000206503.7	2.493E-6	0	7968	gtex_brain_putamen_basal
rs1655904	6	29917146	HLA-A	ENSG00000206503.7	1.888E-6	0	8109	gtex_brain_putamen_basal
rs2517716	6	29917260	HLA-A	ENSG00000206503.7	4.845E-8	0	8223	gtex_brain_putamen_basal
rs1632880	6	29917610	HLA-A	ENSG00000206503.7	3.545E-7	0	8573	gtex_brain_putamen_basal
rs1632879	6	29917703	HLA-A	ENSG00000206503.7	3.545E-7	0	8666	gtex_brain_putamen_basal
rs2517713	6	29918099	HLA-A	ENSG00000206503.7	4.251E-8	0	9062	gtex_brain_putamen_basal
rs1655906	6	29918254	HLA-A	ENSG00000206503.7	2.3E-6	0	9217	gtex_brain_putamen_basal
rs2508037	6	29918436	HLA-A	ENSG00000206503.7	4.258E-8	0	9399	gtex_brain_putamen_basal
rs1655907	6	29918587	HLA-A	ENSG00000206503.7	2.3E-6	0	9550	gtex_brain_putamen_basal
rs1655908	6	29918616	HLA-A	ENSG00000206503.7	2.703E-6	0	9579	gtex_brain_putamen_basal
rs1632876	6	29918619	HLA-A	ENSG00000206503.7	2.703E-6	0	9582	gtex_brain_putamen_basal
rs2916806	6	29918684	HLA-A	ENSG00000206503.7	4.246E-8	0	9647	gtex_brain_putamen_basal
rs2975043	6	29918734	HLA-A	ENSG00000206503.7	4.251E-8	0	9697	gtex_brain_putamen_basal
rs2916807	6	29918770	HLA-A	ENSG00000206503.7	4.251E-8	0	9733	gtex_brain_putamen_basal
rs9260403	6	29918861	HLA-A	ENSG00000206503.7	4.26E-8	0	9824	gtex_brain_putamen_basal
rs9260408	6	29918917	HLA-A	ENSG00000206503.7	4.791E-7	0	9880	gtex_brain_putamen_basal
rs9260413	6	29919010	HLA-A	ENSG00000206503.7	4.812E-8	0	9973	gtex_brain_putamen_basal
rs9260414	6	29919020	HLA-A	ENSG00000206503.7	1.495E-7	0	9983	gtex_brain_putamen_basal
rs9260424	6	29919098	HLA-A	ENSG00000206503.7	4.1E-8	0	10061	gtex_brain_putamen_basal
rs547275509	6	29919141	HLA-A	ENSG00000206503.7	4.324E-8	0	10104	gtex_brain_putamen_basal
rs2517709	6	29919421	HLA-A	ENSG00000206503.7	4.833E-8	0	10384	gtex_brain_putamen_basal
rs2517706	6	29919659	HLA-A	ENSG00000206503.7	4.778E-8	0	10622	gtex_brain_putamen_basal
rs7747114	6	29919774	HLA-A	ENSG00000206503.7	5.884E-8	0	10737	gtex_brain_putamen_basal
rs7747253	6	29919779	HLA-A	ENSG00000206503.7	6.853E-7	0	10742	gtex_brain_putamen_basal
rs9260463	6	29919862	HLA-A	ENSG00000206503.7	4.281E-8	0	10825	gtex_brain_putamen_basal
rs9260464	6	29919864	HLA-A	ENSG00000206503.7	4.281E-8	0	10827	gtex_brain_putamen_basal
rs9260468	6	29920000	HLA-A	ENSG00000206503.7	6.748E-8	0	10963	gtex_brain_putamen_basal
rs1655910	6	29920105	HLA-A	ENSG00000206503.7	7.504E-8	0	11068	gtex_brain_putamen_basal
rs9260483	6	29920238	HLA-A	ENSG00000206503.7	1.403E-7	0	11201	gtex_brain_putamen_basal
rs9260484	6	29920253	HLA-A	ENSG00000206503.7	1.403E-7	0	11216	gtex_brain_putamen_basal
rs9260486	6	29920281	HLA-A	ENSG00000206503.7	1.393E-7	0	11244	gtex_brain_putamen_basal
rs554052992	6	29920465	HLA-A	ENSG00000206503.7	5.969E-7	0	11428	gtex_brain_putamen_basal
rs2975042	6	29920536	HLA-A	ENSG00000206503.7	4.251E-8	0	11499	gtex_brain_putamen_basal
rs2916809	6	29920549	HLA-A	ENSG00000206503.7	4.251E-8	0	11512	gtex_brain_putamen_basal
rs576595600	6	29920841	HLA-A	ENSG00000206503.7	8.186E-9	0	11804	gtex_brain_putamen_basal
rs9260512	6	29920883	HLA-A	ENSG00000206503.7	3.02E-8	0	11846	gtex_brain_putamen_basal
rs9260521	6	29921135	HLA-A	ENSG00000206503.7	3.105E-8	0	12098	gtex_brain_putamen_basal
rs9260524	6	29921158	HLA-A	ENSG00000206503.7	3.111E-8	0	12121	gtex_brain_putamen_basal
rs9260530	6	29921220	HLA-A	ENSG00000206503.7	1.24E-8	0	12183	gtex_brain_putamen_basal
rs2735092	6	29921262	HLA-A	ENSG00000206503.7	8.157E-9	0	12225	gtex_brain_putamen_basal
rs111867975	6	29921542	HLA-A	ENSG00000206503.7	4.468E-8	0	12505	gtex_brain_putamen_basal
rs9260555	6	29921773	HLA-A	ENSG00000206503.7	2.504E-8	0	12736	gtex_brain_putamen_basal
rs9260559	6	29921822	HLA-A	ENSG00000206503.7	2.334E-8	0	12785	gtex_brain_putamen_basal
rs9260565	6	29921880	HLA-A	ENSG00000206503.7	2.466E-8	0	12843	gtex_brain_putamen_basal
rs1655914	6	29921927	HLA-A	ENSG00000206503.7	2.392E-6	0	12890	gtex_brain_putamen_basal
rs5027910	6	29922073	HLA-A	ENSG00000206503.7	2.775E-8	0	13036	gtex_brain_putamen_basal
rs1632874	6	29922123	HLA-A	ENSG00000206503.7	2.786E-6	0	13086	gtex_brain_putamen_basal
rs5027912	6	29922177	HLA-A	ENSG00000206503.7	2.735E-8	0	13140	gtex_brain_putamen_basal
rs5027913	6	29922199	HLA-A	ENSG00000206503.7	2.689E-8	0	13162	gtex_brain_putamen_basal
rs9260584	6	29922448	HLA-A	ENSG00000206503.7	1.585E-6	0	13411	gtex_brain_putamen_basal
rs9260599	6	29922653	HLA-A	ENSG00000206503.7	4.251E-8	0	13616	gtex_brain_putamen_basal
rs1655915	6	29922934	HLA-A	ENSG00000206503.7	1.618E-6	0	13897	gtex_brain_putamen_basal
rs9260614	6	29922995	HLA-A	ENSG00000206503.7	2.687E-8	0	13958	gtex_brain_putamen_basal
rs1632873	6	29923497	HLA-A	ENSG00000206503.7	1.615E-6	0	14460	gtex_brain_putamen_basal
rs2571390	6	29923554	HLA-A	ENSG00000206503.7	9.323E-8	0	14517	gtex_brain_putamen_basal
rs2844810	6	29923580	HLA-A	ENSG00000206503.7	4.22E-8	0	14543	gtex_brain_putamen_basal

Section II. Transcriptome annotation

General gene expression (GTEx)

Gene expression during devlopment (BrainCloud)

Footnote:
A total of 269 time points ploted, with n=38 fetal samples (x=1:38). Each triangle represents one time point.

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
HLA-DRB5	0.86	0.91
CD74	0.84	0.88
HLA-DQB1	0.82	0.82
HLA-DPA1	0.79	0.86
HLA-DRA	0.79	0.84
HLA-DPB1	0.79	0.81
ANXA11	0.74	0.81
HLA-DMB	0.74	0.77
CTSF	0.73	0.72
ME1	0.73	0.80

Top 10 negatively co-expressed genes
Gene	Pearson's Correlation	Spearman's Correlation
KIAA1949	-0.59	-0.59
TUBB2B	-0.58	-0.65
SH3BP2	-0.58	-0.66
NKIRAS2	-0.57	-0.55
ZNF300	-0.57	-0.56
AL033532.1	-0.56	-0.58
ZNF311	-0.56	-0.59
ZNF551	-0.56	-0.56
CCDC123	-0.56	-0.55
AC004017.1	-0.56	-0.56

Section III. Gene Ontology annotation

Molecular function	GO term	Evidence	Neuro keywords	PubMed ID
GO:0005515	protein binding	IPI		12414957 \|17353931
GO:0032393	MHC class I receptor activity	NAS		1431115 \|2437024 \|2715640 \|6609814 \|8188325
Biological process	GO term	Evidence	Neuro keywords	PubMed ID
GO:0002474	antigen processing and presentation of peptide antigen via MHC class I	IEA		-
GO:0019882	antigen processing and presentation	IEA		-
GO:0006955	immune response	IEA		-
GO:0006955	immune response	NAS		1431115 \|2437024 \|2715640 \|6609814 \|8188325
GO:0044419	interspecies interaction between organisms	IEA		-
Cellular component	GO term	Evidence	Neuro keywords	PubMed ID
GO:0000139	Golgi membrane	EXP		15569716
GO:0016020	membrane	IEA		-
GO:0016021	integral to membrane	IEA		-
GO:0005887	integral to plasma membrane	NAS		1431115 \|2437024 \|2715640 \|6609814 \|8188325
GO:0042612	MHC class I protein complex	IEA		-
GO:0031901	early endosome membrane	EXP		15569716

Section IV. Protein-protein interaction annotation

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
B2M	-	beta-2-microglobulin	-	HPRD	93026
CALR	CRT \| FLJ26680 \| RO \| SSA \| cC1qR	calreticulin	CRT interacts with HLA-A2. This interaction was modeled on a demonstrated interaction between rabbit CRT and human HLA-A2.	BIND	15383281
CD8A	CD8 \| Leu2 \| MAL \| p32	CD8a molecule	-	HPRD,BioGRID	9177355 \|10809759\|10809759
COPB1	COPB \| DKFZp761K102 \| FLJ10341	coatomer protein complex, subunit beta 1	Affinity Capture-Western	BioGRID	11884415
COPG	COPG1 \| FLJ21068	coatomer protein complex, subunit gamma	Affinity Capture-Western	BioGRID	11884415
DERL1	DER-1 \| DER1 \| FLJ13784 \| FLJ42092 \| MGC3067 \| PRO2577	Der1-like domain family, member 1	-	HPRD,BioGRID	15215855
ERBB2	CD340 \| HER-2 \| HER-2/neu \| HER2 \| NEU \| NGL \| TKR1	v-erb-b2 erythroblastic leukemia viral oncogene homolog 2, neuro/glioblastoma derived oncogene homolog (avian)	-	HPRD,BioGRID	10593938
KIR3DL2	CD158K \| MGC125321 \| NKAT4 \| NKAT4B \| p140	killer cell immunoglobulin-like receptor, three domains, long cytoplasmic tail, 2	-	HPRD,BioGRID	8617928 \|8760804
LILRB1	CD85 \| CD85J \| FLJ37515 \| ILT2 \| LIR-1 \| LIR1 \| MIR-7 \| MIR7	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 1	-	HPRD,BioGRID	12897781
LILRB2	CD85D \| ILT4 \| LILRA6 \| LIR-2 \| LIR2 \| MIR-10 \| MIR10	leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2	-	HPRD,BioGRID	9531263 \|12853576
MAGEA1	MAGE1 \| MGC9326	melanoma antigen family A, 1 (directs expression of antigen MZ2-E)	Reconstituted Complex	BioGRID	8647853
MAGEA4	MAGE-41 \| MAGE-X2 \| MAGE4 \| MAGE4A \| MAGE4B \| MGC21336	melanoma antigen family A, 4	-	HPRD,BioGRID	11502003
TAP1	ABC17 \| ABCB2 \| APT1 \| D6S114E \| FLJ26666 \| FLJ41500 \| PSF1 \| RING4 \| TAP1*0102N \| TAP1N	transporter 1, ATP-binding cassette, sub-family B (MDR/TAP)	Affinity Capture-Western	BioGRID	11884415
TAPBP	NGS17 \| TAPA \| TPN \| TPSN \| tapasin	TAP binding protein (tapasin)	-	HPRD	8769474
TAPBP	NGS17 \| TAPA \| TPN \| TPSN \| tapasin	TAP binding protein (tapasin)	Affinity Capture-Western	BioGRID	11884415
TRA@	FLJ22602 \| MGC117436 \| MGC22624 \| MGC23964 \| MGC71411 \| TCRA \| TCRD \| TRA	T cell receptor alpha locus	-	HPRD,BioGRID	9586631
TRB@	TCRB \| TRB	T cell receptor beta locus	Co-crystal Structure	BioGRID	9586631
UGCGL1	FLJ23671 \| FLJ23796 \| HUGT1	UDP-glucose ceramide glucosyltransferase-like 1	Affinity Capture-MS	BioGRID	17353931

Section V. Pathway annotation

Pathway name	Pathway size	# SZGR 2.0 genes in pathway	Info
KEGG ENDOCYTOSIS	183	132	All SZGR 2.0 genes in this pathway
KEGG CELL ADHESION MOLECULES CAMS	134	93	All SZGR 2.0 genes in this pathway
KEGG ANTIGEN PROCESSING AND PRESENTATION	89	65	All SZGR 2.0 genes in this pathway
KEGG NATURAL KILLER CELL MEDIATED CYTOTOXICITY	137	92	All SZGR 2.0 genes in this pathway
KEGG TYPE I DIABETES MELLITUS	44	38	All SZGR 2.0 genes in this pathway
KEGG AUTOIMMUNE THYROID DISEASE	53	49	All SZGR 2.0 genes in this pathway
KEGG ALLOGRAFT REJECTION	38	34	All SZGR 2.0 genes in this pathway
KEGG GRAFT VERSUS HOST DISEASE	42	31	All SZGR 2.0 genes in this pathway
KEGG VIRAL MYOCARDITIS	73	58	All SZGR 2.0 genes in this pathway
BIOCARTA CTL PATHWAY	15	11	All SZGR 2.0 genes in this pathway
BIOCARTA NKCELLS PATHWAY	20	13	All SZGR 2.0 genes in this pathway
PID IL12 2PATHWAY	63	54	All SZGR 2.0 genes in this pathway
PID CD8 TCR PATHWAY	53	42	All SZGR 2.0 genes in this pathway
PID AP1 PATHWAY	70	60	All SZGR 2.0 genes in this pathway
PID CD8 TCR DOWNSTREAM PATHWAY	65	56	All SZGR 2.0 genes in this pathway
REACTOME NEF MEDIATED DOWNREGULATION OF MHC CLASS I COMPLEX CELL SURFACE EXPRESSION	10	5	All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN PROCESSING CROSS PRESENTATION	76	48	All SZGR 2.0 genes in this pathway
REACTOME ENDOSOMAL VACUOLAR PATHWAY	9	7	All SZGR 2.0 genes in this pathway
REACTOME ER PHAGOSOME PATHWAY	61	40	All SZGR 2.0 genes in this pathway
REACTOME NEF MEDIATES DOWN MODULATION OF CELL SURFACE RECEPTORS BY RECRUITING THEM TO CLATHRIN ADAPTERS	21	12	All SZGR 2.0 genes in this pathway
REACTOME IMMUNOREGULATORY INTERACTIONS BETWEEN A LYMPHOID AND A NON LYMPHOID CELL	70	37	All SZGR 2.0 genes in this pathway
REACTOME INTERFERON GAMMA SIGNALING	63	48	All SZGR 2.0 genes in this pathway
REACTOME INTERFERON ALPHA BETA SIGNALING	64	50	All SZGR 2.0 genes in this pathway
REACTOME INTERFERON SIGNALING	159	116	All SZGR 2.0 genes in this pathway
REACTOME HIV INFECTION	207	122	All SZGR 2.0 genes in this pathway
REACTOME HOST INTERACTIONS OF HIV FACTORS	132	81	All SZGR 2.0 genes in this pathway
REACTOME THE ROLE OF NEF IN HIV1 REPLICATION AND DISEASE PATHOGENESIS	28	19	All SZGR 2.0 genes in this pathway
REACTOME IMMUNE SYSTEM	933	616	All SZGR 2.0 genes in this pathway
REACTOME ADAPTIVE IMMUNE SYSTEM	539	350	All SZGR 2.0 genes in this pathway
REACTOME CYTOKINE SIGNALING IN IMMUNE SYSTEM	270	204	All SZGR 2.0 genes in this pathway
REACTOME ANTIGEN PRESENTATION FOLDING ASSEMBLY AND PEPTIDE LOADING OF CLASS I MHC	21	17	All SZGR 2.0 genes in this pathway
REACTOME CLASS I MHC MEDIATED ANTIGEN PROCESSING PRESENTATION	251	156	All SZGR 2.0 genes in this pathway
DOANE RESPONSE TO ANDROGEN DN	241	146	All SZGR 2.0 genes in this pathway
ENK UV RESPONSE KERATINOCYTE UP	530	342	All SZGR 2.0 genes in this pathway
WANG ESOPHAGUS CANCER VS NORMAL UP	121	72	All SZGR 2.0 genes in this pathway
EBAUER TARGETS OF PAX3 FOXO1 FUSION UP	207	128	All SZGR 2.0 genes in this pathway
DACOSTA UV RESPONSE VIA ERCC3 UP	309	199	All SZGR 2.0 genes in this pathway
JAZAG TGFB1 SIGNALING UP	108	69	All SZGR 2.0 genes in this pathway
ALCALA APOPTOSIS	88	60	All SZGR 2.0 genes in this pathway
MANTOVANI VIRAL GPCR SIGNALING DN	49	37	All SZGR 2.0 genes in this pathway
LIU NASOPHARYNGEAL CARCINOMA	70	38	All SZGR 2.0 genes in this pathway
SCHAEFFER PROSTATE DEVELOPMENT 48HR UP	487	286	All SZGR 2.0 genes in this pathway
COLIN PILOCYTIC ASTROCYTOMA VS GLIOBLASTOMA UP	35	32	All SZGR 2.0 genes in this pathway
BENPORATH EED TARGETS	1062	725	All SZGR 2.0 genes in this pathway
BENPORATH ES WITH H3K27ME3	1118	744	All SZGR 2.0 genes in this pathway
BENPORATH MYC MAX TARGETS	775	494	All SZGR 2.0 genes in this pathway
IIZUKA LIVER CANCER PROGRESSION L0 L1 DN	21	14	All SZGR 2.0 genes in this pathway
DER IFN ALPHA RESPONSE UP	74	48	All SZGR 2.0 genes in this pathway
WIELAND UP BY HBV INFECTION	101	66	All SZGR 2.0 genes in this pathway
DER IFN BETA RESPONSE UP	102	67	All SZGR 2.0 genes in this pathway
SANA RESPONSE TO IFNG UP	78	50	All SZGR 2.0 genes in this pathway
SANA TNF SIGNALING UP	83	56	All SZGR 2.0 genes in this pathway
SHIPP DLBCL VS FOLLICULAR LYMPHOMA DN	45	28	All SZGR 2.0 genes in this pathway
FLECHNER BIOPSY KIDNEY TRANSPLANT OK VS DONOR UP	555	346	All SZGR 2.0 genes in this pathway
DER IFN GAMMA RESPONSE UP	71	45	All SZGR 2.0 genes in this pathway
CHIBA RESPONSE TO TSA UP	52	33	All SZGR 2.0 genes in this pathway
RODWELL AGING KIDNEY UP	487	303	All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 6HR UP	953	554	All SZGR 2.0 genes in this pathway
KRIGE RESPONSE TO TOSEDOSTAT 24HR UP	783	442	All SZGR 2.0 genes in this pathway
KIM LRRC3B TARGETS	30	24	All SZGR 2.0 genes in this pathway
PELLICCIOTTA HDAC IN ANTIGEN PRESENTATION DN	49	38	All SZGR 2.0 genes in this pathway
GAURNIER PSMD4 TARGETS	73	55	All SZGR 2.0 genes in this pathway
GOLDRATH ANTIGEN RESPONSE	346	192	All SZGR 2.0 genes in this pathway
WUNDER INFLAMMATORY RESPONSE AND CHOLESTEROL DN	12	7	All SZGR 2.0 genes in this pathway
LEE EARLY T LYMPHOCYTE DN	57	36	All SZGR 2.0 genes in this pathway
HSIAO HOUSEKEEPING GENES	389	245	All SZGR 2.0 genes in this pathway
JISON SICKLE CELL DISEASE UP	181	106	All SZGR 2.0 genes in this pathway
KUROKAWA LIVER CANCER EARLY RECURRENCE DN	7	6	All SZGR 2.0 genes in this pathway
SENGUPTA EBNA1 ANTICORRELATED	173	85	All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP	504	321	All SZGR 2.0 genes in this pathway
JOHNSTONE PARVB TARGETS 2 UP	140	94	All SZGR 2.0 genes in this pathway
PEDERSEN METASTASIS BY ERBB2 ISOFORM 7	403	240	All SZGR 2.0 genes in this pathway
PHONG TNF RESPONSE NOT VIA P38	337	236	All SZGR 2.0 genes in this pathway

Gene Page: HLA-A