Gene Page: MYH7

Summary
GeneID  4625
Symbol  MYH7
Synonyms  CMD1S|CMH1|DKFZp451F047|MGC138376|MGC138378|MPD1|MYHCB|SPMD|SPMM
Description  myosin, heavy chain 7, cardiac muscle, beta
See related  HGNC:7577|MIM:160760|Ensembl:ENSG00000092054|HPRD:01175|
Locus tag  -
Gene type  protein-coding
Map location  14q12
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.047 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
GOLIM40.860.85
TLN10.850.85
DOCK10.830.82
RIN20.800.79
LRIG10.800.84
FGFR20.800.77
KIAA11610.800.82
BMP70.790.78
GPT20.790.76
USP400.790.79
Top 10 negatively co-expressed genes
C20orf7-0.46-0.50
PSMA6-0.42-0.49
ZNF32-0.41-0.47
GTF3A-0.41-0.45
COX5A-0.40-0.42
ST20-0.40-0.44
HINT1-0.40-0.42
NDUFAF2-0.40-0.44
NOP10-0.39-0.45
PFDN5-0.39-0.47
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000146microfilament motor activityNAS3021460 
GO:0000166nucleotide bindingIEA-
GO:0003779actin bindingIEA-
GO:0005516calmodulin bindingIEA-
GO:0005524ATP bindingIC16088376 
GO:0008307structural constituent of muscleIDA15621050 |16088376 
GO:0016887ATPase activityIDA15621050 
GO:0030898actin-dependent ATPase activityIMP16088376 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0002027regulation of heart rateIDA15621050 
GO:0055010ventricular cardiac muscle morphogenesisIMP15856146 
GO:0006200ATP catabolic processIDA15621050 
GO:0007512adult heart developmentIMP15856146 
GO:0006941striated muscle contractionIEA-
GO:0030049muscle filament slidingIMP8514894 |16088376 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005863striated muscle thick filamentIEA-
GO:0005634nucleusIDA18029348 
GO:0005730nucleolusIDA18029348 
GO:0005737cytoplasmIEA-
GO:0005925focal adhesionIDA18029348 
GO:0016459myosin complexTAS12933792 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
NTHL1NTH1 | OCTS3nth endonuclease III-like 1 (E. coli)Affinity Capture-MSBioGRID17353931 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_CARDIAC_MUSCLE_CONTRACTION 8051All SZGR genes in this pathway
KEGG_TIGHT_JUNCTION 13486All SZGR genes in this pathway
KEGG_HYPERTROPHIC_CARDIOMYOPATHY_HCM 8565All SZGR genes in this pathway
KEGG_DILATED_CARDIOMYOPATHY 9268All SZGR genes in this pathway
KEGG_VIRAL_MYOCARDITIS 7358All SZGR genes in this pathway
SHETH_LIVER_CANCER_VS_TXNIP_LOSS_PAM5 9459All SZGR genes in this pathway
AFFAR_YY1_TARGETS_UP 214133All SZGR genes in this pathway
LEE_AGING_CEREBELLUM_DN 8666All SZGR genes in this pathway
LEE_CALORIE_RESTRICTION_MUSCLE_UP 4333All SZGR genes in this pathway
ACEVEDO_METHYLATED_IN_LIVER_CANCER_DN 940425All SZGR genes in this pathway
YOSHIMURA_MAPK8_TARGETS_UP 1305895All SZGR genes in this pathway
SWEET_LUNG_CANCER_KRAS_UP 491316All SZGR genes in this pathway
SWEET_KRAS_ONCOGENIC_SIGNATURE 8956All SZGR genes in this pathway
HOFFMANN_SMALL_PRE_BII_TO_IMMATURE_B_LYMPHOCYTE_UP 7049All SZGR genes in this pathway
YAO_TEMPORAL_RESPONSE_TO_PROGESTERONE_CLUSTER_1 6850All SZGR genes in this pathway
VANDESLUIS_COMMD1_TARGETS_GROUP_3_UP 8950All SZGR genes in this pathway
WANG_NFKB_TARGETS 2515All SZGR genes in this pathway
CHEMELLO_SOLEUS_VS_EDL_MYOFIBERS_UP 3516All SZGR genes in this pathway


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