Gene Page: MAML3

Summary
GeneID  55534
Symbol  MAML3
Synonyms  CAGH3|ERDA3|GDN|MAM-2|MAM2|TNRC3
Description  mastermind-like 3 (Drosophila)
See related  HGNC:16272|MIM:608991|HPRD:10066|
Locus tag  -
Gene type  protein-coding
Map location  4q28
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 1 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
PRPSAP20.960.94
HSF20.960.94
PTBP20.950.92
GART0.950.91
GPN10.950.93
DHX570.950.91
GSTA40.940.94
HMGN40.940.93
PWP10.940.93
POLR2B0.940.91
Top 10 negatively co-expressed genes
AF347015.27-0.76-0.89
MT-CO2-0.75-0.88
HLA-F-0.74-0.77
AF347015.33-0.74-0.88
AF347015.31-0.74-0.87
AIFM3-0.74-0.77
MT-CYB-0.74-0.88
AF347015.8-0.73-0.89
AF347015.15-0.71-0.88
HEPN1-0.71-0.76
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityTAS9225980 
GO:0003713transcription coactivator activityIDA12370315 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0007399nervous system developmentTASneurite (GO term level: 5)9225980 
GO:0006355regulation of transcription, DNA-dependentIEA-
GO:0006350transcriptionIEA-
GO:0007219Notch signaling pathwayIDA12370315 
GO:0045944positive regulation of transcription from RNA polymerase II promoterIDA12370315 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusIDA12370315 
GO:0005634nucleusTAS9225980 
GO:0016607nuclear speckIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CSHL1CS-5 | CSHP1 | CSL | MGC149868 | hCS-Lchorionic somatomammotropin hormone-like 1Affinity Capture-WesternBioGRID12370315 
MAML1KIAA0200 | Mam-1 | Mam1mastermind-like 1 (Drosophila)Affinity Capture-WesternBioGRID12370315 
NOTCH1TAN1 | hN1Notch homolog 1, translocation-associated (Drosophila)Two-hybridBioGRID12370315 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_NOTCH_SIGNALING_PATHWAY 4735All SZGR genes in this pathway
REACTOME_PRE_NOTCH_TRANSCRIPTION_AND_TRANSLATION 2917All SZGR genes in this pathway
REACTOME_PRE_NOTCH_EXPRESSION_AND_PROCESSING 4424All SZGR genes in this pathway
REACTOME_NOTCH1_INTRACELLULAR_DOMAIN_REGULATES_TRANSCRIPTION 4628All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH1 7046All SZGR genes in this pathway
REACTOME_GENERIC_TRANSCRIPTION_PATHWAY 352181All SZGR genes in this pathway
REACTOME_NOTCH_HLH_TRANSCRIPTION_PATHWAY 138All SZGR genes in this pathway
REACTOME_SIGNALING_BY_NOTCH 10364All SZGR genes in this pathway
DEURIG_T_CELL_PROLYMPHOCYTIC_LEUKEMIA_UP 368234All SZGR genes in this pathway
SENESE_HDAC3_TARGETS_UP 501327All SZGR genes in this pathway
RODRIGUES_THYROID_CARCINOMA_ANAPLASTIC_DN 537339All SZGR genes in this pathway
RODRIGUES_NTN1_AND_DCC_TARGETS 3525All SZGR genes in this pathway
MARCHINI_TRABECTEDIN_RESISTANCE_UP 2116All SZGR genes in this pathway
XU_GH1_AUTOCRINE_TARGETS_UP 268157All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_6HR_UP 953554All SZGR genes in this pathway
KRIGE_RESPONSE_TO_TOSEDOSTAT_24HR_UP 783442All SZGR genes in this pathway
MOLENAAR_TARGETS_OF_CCND1_AND_CDK4_UP 6748All SZGR genes in this pathway
CHUNG_BLISTER_CYTOTOXICITY_DN 4429All SZGR genes in this pathway
TAYLOR_METHYLATED_IN_ACUTE_LYMPHOBLASTIC_LEUKEMIA 7752All SZGR genes in this pathway
LEE_RECENT_THYMIC_EMIGRANT 227128All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-101237923861A,m8hsa-miR-101UACAGUACUGUGAUAACUGAAG
miR-133211121181A,m8hsa-miR-133aUUGGUCCCCUUCAACCAGCUGU
hsa-miR-133bUUGGUCCCCUUCAACCAGCUA
miR-13720122018m8hsa-miR-137UAUUGCUUAAGAAUACGCGUAG
miR-144238023861Ahsa-miR-144UACAGUAUAGAUGAUGUACUAG
miR-204/211279428011A,m8hsa-miR-204brainUUCCCUUUGUCAUCCUAUGCCU
hsa-miR-211UUCCCUUUGUCAUCCUUCGCCU
miR-485-3p23832389m8hsa-miR-485-3pGUCAUACACGGCUCUCCUCUCU
miR-486199320001A,m8hsa-miR-486UCCUGUACUGAGCUGCCCCGAG
miR-493-5p24792485m8hsa-miR-493-5pUUGUACAUGGUAGGCUUUCAUU
miR-49522882294m8hsa-miR-495brainAAACAAACAUGGUGCACUUCUUU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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