Gene Page: NGLY1

Summary
GeneID  55768
Symbol  NGLY1
Synonyms  FLJ11005|FLJ12409|PNG1
Description  N-glycanase 1
See related  HGNC:17646|MIM:610661|Ensembl:ENSG00000151092|HPRD:10118|
Locus tag  -
Gene type  protein-coding
Map location  3p24.2
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.006 
ExpressionExpressionP value: 1.638 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CTNND20.810.74
TMEM167B0.810.76
NDRG10.810.77
GPD1L0.800.76
HERC30.800.74
NNT0.800.75
FAM124A0.790.74
MARS20.790.77
RP1-21O18.10.790.77
WASF10.790.70
Top 10 negatively co-expressed genes
AF347015.21-0.62-0.62
C11orf67-0.58-0.58
MT-CO2-0.58-0.58
AF347015.8-0.55-0.55
NOSTRIN-0.55-0.53
GNG11-0.55-0.52
AC098691.2-0.54-0.55
AF347015.27-0.54-0.55
AF347015.31-0.54-0.54
AL138743.2-0.54-0.52
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0000224peptide-N4-(N-acetyl-beta-glucosaminyl)asparagine amidase activityIEA-
GO:0005515protein bindingIPI15358861 
GO:0016787hydrolase activityIEA-
GO:0008270zinc ion bindingIEA-
GO:0046872metal ion bindingIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006516glycoprotein catabolic processIDA15358861 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005737cytoplasmIDA15358861 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
RAD23BHHR23B | HR23B | P58RAD23 homolog B (S. cerevisiae)-HPRD11562482 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
ZHONG_RESPONSE_TO_AZACITIDINE_AND_TSA_DN 7038All SZGR genes in this pathway
LIU_VMYB_TARGETS_UP 12778All SZGR genes in this pathway
WANG_RESPONSE_TO_ANDROGEN_UP 2921All SZGR genes in this pathway
WANG_RESPONSE_TO_FORSKOLIN_UP 2317All SZGR genes in this pathway
LASTOWSKA_NEUROBLASTOMA_COPY_NUMBER_DN 800473All SZGR genes in this pathway
INGRAM_SHH_TARGETS_UP 12779All SZGR genes in this pathway
HADDAD_B_LYMPHOCYTE_PROGENITOR 293193All SZGR genes in this pathway
ALCALAY_AML_BY_NPM1_LOCALIZATION_DN 184132All SZGR genes in this pathway
DOUGLAS_BMI1_TARGETS_DN 314188All SZGR genes in this pathway
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN 4938All SZGR genes in this pathway
MARSON_BOUND_BY_FOXP3_UNSTIMULATED 1229713All SZGR genes in this pathway
ACEVEDO_LIVER_CANCER_UP 973570All SZGR genes in this pathway
MITSIADES_RESPONSE_TO_APLIDIN_DN 249165All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
MARTENS_TRETINOIN_RESPONSE_DN 841431All SZGR genes in this pathway
PILON_KLF1_TARGETS_DN 19721213All SZGR genes in this pathway
WAKABAYASHI_ADIPOGENESIS_PPARG_BOUND_36HR 2923All SZGR genes in this pathway
NABA_ECM_REGULATORS 238125All SZGR genes in this pathway
NABA_MATRISOME_ASSOCIATED 753411All SZGR genes in this pathway
NABA_MATRISOME 1028559All SZGR genes in this pathway


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