Gene Page: NSFL1C

Summary ?
GeneID55968
SymbolNSFL1C
SynonymsP47|UBX1|UBXD10|UBXN2C|dJ776F14.1
DescriptionNSFL1 (p97) cofactor (p47)
ReferenceMIM:606610|HGNC:HGNC:15912|Ensembl:ENSG00000088833|HPRD:09425|Vega:OTTHUMG00000031665
Gene typeprotein-coding
Map location20p13
Pascal p-value0.018
Sherlock p-value0.99
eGeneMyers' cis & trans
Meta
SupportEXOCYTOSIS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-CONSENSUS
G2Cdb.human_BAYES-COLLINS-HUMAN-PSD-FULL
CompositeSet

Gene in Data Sources
Gene set name Method of gene setDescriptionInfo
CV:PGCnpGenome-wide Association StudyGWAS

Section I. Genetics and epigenetics annotation

@eQTL annotation

SNP IDChromosomePositioneGeneGene Entrez IDpvalueqvalueTSS distanceeQTL type
rs6131468chr201387686NSFL1C559680.15cis
rs4814229chr201388218NSFL1C559680.16cis
rs5019244chr201402160NSFL1C559680.18cis
rs6042244chr201413091NSFL1C559680.03cis
rs6042292chr201419198NSFL1C559680.03cis
rs932524chr201420335NSFL1C559680.01cis
rs3171292chr201423908NSFL1C559680.01cis
rs1499662chr156057848NSFL1C559680.16trans

Section II. Transcriptome annotation

General gene expression (GTEx)

Not available

Gene expression of temporal and spatial changes (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes the lower 25% and upper 25% of the expression distribution.

Top co-expressed genes in brain regions

Top 10 positively co-expressed genes
GenePearson's Correlation Spearman's Correlation
RBM410.810.84
TTC370.810.83
TIAL10.810.85
PLEKHA50.810.83
ZNF6550.800.83
RBL20.800.82
KIAA05280.800.82
USP480.800.82
SENP60.800.82
KIAA17040.790.84
Top 10 negatively co-expressed genes
GenePearson's Correlation Spearman's Correlation
AF347015.31-0.69-0.71
MT-CO2-0.67-0.70
AF347015.21-0.66-0.70
HIGD1B-0.65-0.70
IFI27-0.65-0.69
MT-CYB-0.65-0.67
AF347015.27-0.65-0.68
AF347015.8-0.64-0.68
AF347015.2-0.63-0.67
AF347015.33-0.61-0.64

Section III. Gene Ontology annotation

Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0008289lipid bindingIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005794Golgi apparatusIEA-
GO:0005634nucleusIEA-

Section V. Pathway annotation

Pathway namePathway size# SZGR 2.0 genes in pathwayInfo
CHARAFE BREAST CANCER LUMINAL VS BASAL DN 455304All SZGR 2.0 genes in this pathway
MULLIGHAN MLL SIGNATURE 2 UP 418263All SZGR 2.0 genes in this pathway
KINSEY TARGETS OF EWSR1 FLII FUSION UP 1278748All SZGR 2.0 genes in this pathway
CONCANNON APOPTOSIS BY EPOXOMICIN UP 239157All SZGR 2.0 genes in this pathway
GRAESSMANN APOPTOSIS BY DOXORUBICIN DN 17811082All SZGR 2.0 genes in this pathway
GRAESSMANN RESPONSE TO MC AND DOXORUBICIN DN 770415All SZGR 2.0 genes in this pathway
OLSSON E2F3 TARGETS UP 2814All SZGR 2.0 genes in this pathway
SPIELMAN LYMPHOBLAST EUROPEAN VS ASIAN DN 584395All SZGR 2.0 genes in this pathway
SHEN SMARCA2 TARGETS UP 424268All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE DN 1237837All SZGR 2.0 genes in this pathway
BLALOCK ALZHEIMERS DISEASE INCIPIENT DN 165106All SZGR 2.0 genes in this pathway
MARSON BOUND BY FOXP3 STIMULATED 1022619All SZGR 2.0 genes in this pathway
ACEVEDO NORMAL TISSUE ADJACENT TO LIVER TUMOR DN 354216All SZGR 2.0 genes in this pathway
GRADE COLON CANCER UP 871505All SZGR 2.0 genes in this pathway
PILON KLF1 TARGETS UP 504321All SZGR 2.0 genes in this pathway
KOINUMA TARGETS OF SMAD2 OR SMAD3 824528All SZGR 2.0 genes in this pathway