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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets

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Association Linkage Expression Literature GO_Annotation Gene Network miRNA Targets Datasets Gene Ranking

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Gene Page: RGL2

Summary

GeneID

5863

Symbol

RGL2

Synonyms

HKE1.5|KE1.5|RAB2L

Description

ral guanine nucleotide dissociation stimulator-like 2

Locus tag

DADB-159G18.6

Gene type

protein-coding

Map location

6p21.3

Gene in Data Sources

Gene set name

Method of gene set

Evidence

Info

GSMA_I

genome scan meta-analysis

Psr: 0.033

General Gene Expression (microarray) ?

Gene Expression in Brain Regions (new)

Top co-expressed genes in Brain Regions (new)

Gene

Pearson's Correlation

Spearman's Correlation

Top 10 positively co-expressed genes

Top 10 negatively co-expressed genes

Gene Ontology

Molecular function

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005085

guanyl-nucleotide exchange factor activity

IEA

GO:0005085

guanyl-nucleotide exchange factor activity

NAS

GO:0005088

Ras guanyl-nucleotide exchange factor activity

NAS

8976381

Biological process

GO term

Evidence

Neuro keywords

PubMed ID

GO:0007265

Ras protein signal transduction

NAS

8976381

GO:0007165

signal transduction

IEA

GO:0007264

small GTPase mediated signal transduction

IEA

GO:0051056

regulation of small GTPase mediated signal transduction

IEA

Cellular component

GO term

Evidence

Neuro keywords

PubMed ID

GO:0005575

cellular_component

GO:0005622

intracellular

IEA

Protein-protein Interactions

Shown by network

Interactors	Aliases B	Official full name B	Experimental	Source	PubMed ID
CCDC90B	MDS011 \| MDS025 \| MGC104239	coiled-coil domain containing 90B	Two-hybrid	BioGRID	16169070
CRMP1	DPYSL1 \| DRP-1 \| DRP1	collapsin response mediator protein 1	Two-hybrid	BioGRID	16169070
EEF1G	EF1G \| GIG35	eukaryotic translation elongation factor 1 gamma	Two-hybrid	BioGRID	16169070
HRAS	C-BAS/HAS \| C-H-RAS \| C-HA-RAS1 \| CTLO \| H-RASIDX \| HAMSV \| HRAS1 \| K-RAS \| N-RAS \| RASH1	v-Ha-ras Harvey rat sarcoma viral oncogene homolog	Reconstituted Complex Two-hybrid	BioGRID	8939933 \|15031288
KAT5	ESA1 \| HTATIP \| HTATIP1 \| PLIP \| TIP \| TIP60 \| cPLA2	K(lysine) acetyltransferase 5	Two-hybrid	BioGRID	16169070
MYST2	HBO1 \| HBOA \| KAT7	MYST histone acetyltransferase 2	Two-hybrid	BioGRID	16169070
RAC1	MGC111543 \| MIG5 \| TC-25 \| p21-Rac1	ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1)	Two-hybrid	BioGRID	8939933
RALA	MGC48949 \| RAL	v-ral simian leukemia viral oncogene homolog A (ras related)	Two-hybrid	BioGRID	8939933
RAP1B	DKFZp586H0723 \| K-REV \| RAL1B	RAP1B, member of RAS oncogene family	Reconstituted Complex Two-hybrid	BioGRID	8939933
UNC119	HRG4	unc-119 homolog (C. elegans)	Two-hybrid	BioGRID	16169070

Pathway annotation

Pathway name	Pathway size	# SZGR genes in pathway	Info
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN	634	384	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_BASAL_UP	380	215	All SZGR genes in this pathway
CHARAFE_BREAST_CANCER_LUMINAL_VS_MESENCHYMAL_UP	450	256	All SZGR genes in this pathway
BOGNI_TREATMENT_RELATED_MYELOID_LEUKEMIA_DN	33	19	All SZGR genes in this pathway
CREIGHTON_AKT1_SIGNALING_VIA_MTOR_DN	23	16	All SZGR genes in this pathway
FRIDMAN_SENESCENCE_UP	77	60	All SZGR genes in this pathway
BENPORATH_MYC_MAX_TARGETS	775	494	All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_QTL_TRANS	882	572	All SZGR genes in this pathway
HSIAO_LIVER_SPECIFIC_GENES	244	154	All SZGR genes in this pathway
YU_MYC_TARGETS_DN	55	38	All SZGR genes in this pathway
MA_MYELOID_DIFFERENTIATION_UP	39	29	All SZGR genes in this pathway
JAZAERI_BREAST_CANCER_BRCA1_VS_BRCA2_DN	43	31	All SZGR genes in this pathway
DANG_BOUND_BY_MYC	1103	714	All SZGR genes in this pathway
LI_INDUCED_T_TO_NATURAL_KILLER_DN	116	83	All SZGR genes in this pathway

miRNA Targets ?

miRNA family	Target position			miRNA ID	miRNA seq
miRNA family	UTR start	UTR end	Match method	miRNA ID	miRNA seq
miR-128	401	408	1A,m8	hsa-miR-128a	UCACAGUGAACCGGUCUCUUUU
miR-128	401	408	1A,m8	hsa-miR-128b	UCACAGUGAACCGGUCUCUUUC
miR-142-3p	432	438	m8	hsa-miR-142-3p	UGUAGUGUUUCCUACUUUAUGGA
miR-196	434	440	m8	hsa-miR-196a	UAGGUAGUUUCAUGUUGUUGG
miR-196	434	440	m8	hsa-miR-196b	UAGGUAGUUUCCUGUUGUUGG
miR-24	324	330	m8	hsa-miR-24^SZ	UGGCUCAGUUCAGCAGGAACAG
miR-27	402	408	m8	hsa-miR-27a^brain	UUCACAGUGGCUAAGUUCCGC
miR-27	402	408	m8	hsa-miR-27b^brain	UUCACAGUGGCUAAGUUCUGC

SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.