Gene Page: SOX1

Summary
GeneID  6656
Symbol  SOX1
Synonyms  -
Description  SRY (sex determining region Y)-box 1
See related  HGNC:11189|MIM:602148|Ensembl:ENSG00000182968|HPRD:03687|
Locus tag  -
Gene type  protein-coding
Map location  13q34
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GO_AnnotationMapping neuro-related keywords to Gene Ontology annotationsHits with neuro-related keywords: 3 
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
LILRA40.690.59
CLDND10.670.75
C10orf1280.650.65
CNDP10.650.53
SLC31A20.650.68
TMEM1440.640.64
LRP20.640.66
LASS20.640.75
RNF130.640.69
PLA2G70.630.62
Top 10 negatively co-expressed genes
OLFM2-0.31-0.37
EMID1-0.30-0.44
TBC1D10A-0.29-0.33
WDR86-0.27-0.39
SLC29A4-0.27-0.32
KLHL1-0.27-0.25
SCUBE1-0.27-0.40
RPRM-0.27-0.30
PPAPR5-0.27-0.24
MPPED1-0.26-0.23
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0003700transcription factor activityNAS9337405 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0001764neuron migrationIEAneuron (GO term level: 8)-
GO:0030900forebrain developmentIEABrain (GO term level: 8)-
GO:0021884forebrain neuron developmentIEAneuron, Brain (GO term level: 11)-
GO:0006355regulation of transcription, DNA-dependentNAS9337405 
GO:0006325establishment or maintenance of chromatin architectureNAS9337405 
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005634nucleusNAS9337405 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
RIZ_ERYTHROID_DIFFERENTIATION_HBZ 4127All SZGR genes in this pathway
RIZ_ERYTHROID_DIFFERENTIATION_HEMGN 3121All SZGR genes in this pathway
ROVERSI_GLIOMA_COPY_NUMBER_DN 5437All SZGR genes in this pathway
DAWSON_METHYLATED_IN_LYMPHOMA_TCL1 5945All SZGR genes in this pathway
HATADA_METHYLATED_IN_LUNG_CANCER_UP 390236All SZGR genes in this pathway
BENPORATH_SUZ12_TARGETS 1038678All SZGR genes in this pathway
BENPORATH_EED_TARGETS 1062725All SZGR genes in this pathway
TESAR_ALK_TARGETS_HUMAN_ES_5D_UP 55All SZGR genes in this pathway
HU_GENOTOXIN_ACTION_DIRECT_VS_INDIRECT_4HR 3722All SZGR genes in this pathway
XU_GH1_EXOGENOUS_TARGETS_DN 12069All SZGR genes in this pathway
TESAR_ALK_TARGETS_EPISC_3D_UP 77All SZGR genes in this pathway
MEISSNER_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 142103All SZGR genes in this pathway
MEISSNER_BRAIN_HCP_WITH_H3K4ME3_AND_H3K27ME3 1069729All SZGR genes in this pathway
MIKKELSEN_NPC_HCP_WITH_H3K4ME3_AND_H3K27ME3 210148All SZGR genes in this pathway
MIKKELSEN_MEF_HCP_WITH_H3K27ME3 590403All SZGR genes in this pathway
BROWNE_HCMV_INFECTION_4HR_DN 254158All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_B 549316All SZGR genes in this pathway
miRNA Targets ?
miRNA familyTarget positionmiRNA IDmiRNA seq
UTR startUTR endMatch method
miR-13916551661m8hsa-miR-139brainUCUACAGUGCACGUGUCU
miR-155162716341A,m8hsa-miR-155UUAAUGCUAAUCGUGAUAGGGG
miR-200bc/429256262m8hsa-miR-200bUAAUACUGCCUGGUAAUGAUGAC
hsa-miR-200cUAAUACUGCCGGGUAAUGAUGG
hsa-miR-429UAAUACUGUCUGGUAAAACCGU
miR-221/222165716631Ahsa-miR-221brainAGCUACAUUGUCUGCUGGGUUUC
hsa-miR-222brainAGCUACAUCUGGCUACUGGGUCUC
miR-410565571m8hsa-miR-410AAUAUAACACAGAUGGCCUGU
  • SZ: miRNAs which differentially expressed in brain cortex of schizophrenia patients comparing with control samples using microarray. Click here to see the list of SZ related miRNAs.
  • Brain: miRNAs which are expressed in brain based on miRNA microarray expression studies. Click here to see the list of brain related miRNAs.


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