Gene Page: TAPBP

Summary
GeneID  6892
Symbol  TAPBP
Synonyms  NGS17|TAPA|TPN|TPSN|tapasin
Description  TAP binding protein (tapasin)
See related  HGNC:11566|MIM:601962|Ensembl:ENSG00000112493|HPRD:09061|
Locus tag  DAMC-227D19.13
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenia, schizophrenias, schizophrenic]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
CCDC1350.730.29
RFX20.720.60
CCDC1140.710.46
RIBC10.710.34
CCDC110.700.28
C1orf920.700.28
MYLK30.690.29
FAM179A0.690.30
GLB1L0.690.42
NEK50.680.30
Top 10 negatively co-expressed genes
EPHX4-0.24-0.22
ABCC12-0.22-0.23
KRT17-0.21-0.19
SPHAR-0.21-0.29
SLC26A4-0.21-0.22
KMO-0.20-0.19
CARD16-0.20-0.21
HSPB3-0.20-0.21
SERPINB2-0.20-0.21
RGS4-0.20-0.10
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0015433peptide antigen-transporting ATPase activityTAS9238042 
GO:0042288MHC class I protein bindingTAS12788224 
GO:0051082unfolded protein bindingTAS12788224 
GO:0042605peptide antigen bindingTAS12788224 
GO:0046979TAP2 bindingTAS12788224 
GO:0046978TAP1 bindingTAS12788224 
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006461protein complex assemblyTAS9271576 
GO:0019885antigen processing and presentation of endogenous peptide antigen via MHC class IIEA-
GO:0006955immune responseTAS9271576 
GO:0006890retrograde vesicle-mediated transport, Golgi to ERNAS11884415 
GO:0050823peptide antigen stabilizationISS-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0000139Golgi membraneIDA11884415 
GO:0005792microsomeNAS11884415 
GO:0005789endoplasmic reticulum membraneIDA11884415 
GO:0005783endoplasmic reticulumTAS9238042 |9271576 
GO:0016020membraneIEA-
GO:0016021integral to membraneTAS9238042 
GO:0042824MHC class I peptide loading complexNAS12788224 
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
CALRCRT | FLJ26680 | RO | SSA | cC1qRcalreticulin-HPRD,BioGRID8769474 
COPB1COPB | DKFZp761K102 | FLJ10341coatomer protein complex, subunit beta 1-HPRD,BioGRID11884415 
COPGCOPG1 | FLJ21068coatomer protein complex, subunit gamma-HPRD,BioGRID11884415 
HLA-AHLAAmajor histocompatibility complex, class I, A-HPRD8769474 
Affinity Capture-WesternBioGRID11884415 
TAP1ABC17 | ABCB2 | APT1 | D6S114E | FLJ26666 | FLJ41500 | PSF1 | RING4 | TAP1*0102N | TAP1Ntransporter 1, ATP-binding cassette, sub-family B (MDR/TAP)-HPRD,BioGRID12213826 
TAP2ABC18 | ABCB3 | APT2 | D6S217E | PSF2 | RING11transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)-HPRD,BioGRID12213826 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_ANTIGEN_PROCESSING_AND_PRESENTATION 8965All SZGR genes in this pathway
NAKAMURA_TUMOR_ZONE_PERIPHERAL_VS_CENTRAL_DN 634384All SZGR genes in this pathway
ONKEN_UVEAL_MELANOMA_UP 783507All SZGR genes in this pathway
HORIUCHI_WTAP_TARGETS_UP 306188All SZGR genes in this pathway
WANG_CLIM2_TARGETS_UP 269146All SZGR genes in this pathway
OSMAN_BLADDER_CANCER_UP 404246All SZGR genes in this pathway
GINESTIER_BREAST_CANCER_20Q13_AMPLIFICATION_DN 180101All SZGR genes in this pathway
MARKEY_RB1_ACUTE_LOF_UP 215137All SZGR genes in this pathway
GRAESSMANN_APOPTOSIS_BY_DOXORUBICIN_UP 1142669All SZGR genes in this pathway
BERENJENO_TRANSFORMED_BY_RHOA_DN 394258All SZGR genes in this pathway
AUNG_GASTRIC_CANCER 5420All SZGR genes in this pathway
SCHLOSSER_SERUM_RESPONSE_UP 13493All SZGR genes in this pathway
NUYTTEN_EZH2_TARGETS_UP 1037673All SZGR genes in this pathway
LIU_NASOPHARYNGEAL_CARCINOMA 7038All SZGR genes in this pathway
MORI_LARGE_PRE_BII_LYMPHOCYTE_DN 5839All SZGR genes in this pathway
MORI_IMMATURE_B_LYMPHOCYTE_UP 5335All SZGR genes in this pathway
BYSTRYKH_HEMATOPOIESIS_STEM_CELL_AND_BRAIN_QTL_TRANS 185114All SZGR genes in this pathway
WIELAND_UP_BY_HBV_INFECTION 10166All SZGR genes in this pathway
SANA_TNF_SIGNALING_UP 8356All SZGR genes in this pathway
FLECHNER_BIOPSY_KIDNEY_TRANSPLANT_OK_VS_DONOR_UP 555346All SZGR genes in this pathway
GALINDO_IMMUNE_RESPONSE_TO_ENTEROTOXIN 8567All SZGR genes in this pathway
ABBUD_LIF_SIGNALING_1_UP 4629All SZGR genes in this pathway
REN_ALVEOLAR_RHABDOMYOSARCOMA_DN 408274All SZGR genes in this pathway
IVANOVA_HEMATOPOIESIS_STEM_CELL_LONG_TERM 302191All SZGR genes in this pathway
LINDVALL_IMMORTALIZED_BY_TERT_UP 7848All SZGR genes in this pathway
BLALOCK_ALZHEIMERS_DISEASE_UP 16911088All SZGR genes in this pathway
BURTON_ADIPOGENESIS_8 8657All SZGR genes in this pathway
YIH_RESPONSE_TO_ARSENITE_C4 1812All SZGR genes in this pathway
TSENG_IRS1_TARGETS_DN 13588All SZGR genes in this pathway
RODWELL_AGING_KIDNEY_UP 487303All SZGR genes in this pathway
BAELDE_DIABETIC_NEPHROPATHY_DN 434302All SZGR genes in this pathway
KIM_LRRC3B_TARGETS 3024All SZGR genes in this pathway
MONNIER_POSTRADIATION_TUMOR_ESCAPE_DN 373196All SZGR genes in this pathway
PELLICCIOTTA_HDAC_IN_ANTIGEN_PRESENTATION_DN 4938All SZGR genes in this pathway
MARSON_BOUND_BY_E2F4_UNSTIMULATED 728415All SZGR genes in this pathway
ZHANG_BREAST_CANCER_PROGENITORS_DN 14593All SZGR genes in this pathway
GRADE_COLON_CANCER_UP 871505All SZGR genes in this pathway
CHAUHAN_RESPONSE_TO_METHOXYESTRADIOL_DN 10265All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_D7_UP 10767All SZGR genes in this pathway
ICHIBA_GRAFT_VERSUS_HOST_DISEASE_35D_UP 13179All SZGR genes in this pathway
ZHANG_TLX_TARGETS_36HR_UP 221150All SZGR genes in this pathway
MILI_PSEUDOPODIA_CHEMOTAXIS_DN 457302All SZGR genes in this pathway
CAIRO_LIVER_DEVELOPMENT_DN 222141All SZGR genes in this pathway
DASU_IL6_SIGNALING_UP 5944All SZGR genes in this pathway
JOHNSTONE_PARVB_TARGETS_3_UP 430288All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_VIA_TP53_GROUP_A 898516All SZGR genes in this pathway
BRUINS_UVC_RESPONSE_LATE 1137655All SZGR genes in this pathway
LEE_BMP2_TARGETS_UP 745475All SZGR genes in this pathway
PHONG_TNF_RESPONSE_VIA_P38_PARTIAL 160106All SZGR genes in this pathway


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