Gene Page: C4B

Summary
GeneID  721
Symbol  C4B
Synonyms  C4A|C4A13|C4A91|C4B1|C4B12|C4B2|C4B3|C4B5|C4F|CH|CO4|CPAMD3|FLJ60561|MGC164979
Description  complement component 4B (Childo blood group)
See related  HGNC:1324|MIM:120820|Ensembl:ENSG00000204342|HPRD:00402|HPRD:18631|
Locus tag  DADB-112B14.11
Gene type  protein-coding
Map location  6p21.3
 
Gene in Data Sources
Gene set name Method of gene set Evidence Info
AssociationA combined odds ratio method (Sun et al. 2008), association studies2Link to SZGene
GSMA_Igenome scan meta-analysisPsr: 0.033 
LiteratureHigh-throughput literature-searchCo-occurance with Schizophrenia keywords: [schizophrenias, schizophrenia]Click to show detail
 
General Gene Expression (microarray) ?
 
Gene Expression in Brain Regions (new)
 
Top co-expressed genes in Brain Regions (new)
GenePearson's Correlation Spearman's Correlation
Top 10 positively co-expressed genes
Top 10 negatively co-expressed genes
Gene Ontology
Molecular functionGO termEvidenceNeuro keywordsPubMed ID
GO:0005515protein bindingIEA-
GO:0004866endopeptidase inhibitor activityIEA-
Biological processGO termEvidenceNeuro keywordsPubMed ID
GO:0006958complement activation, classical pathwayIEA-
GO:0006954inflammatory responseIEA-
GO:0045087innate immune responseIEA-
Cellular componentGO termEvidenceNeuro keywordsPubMed ID
GO:0005576extracellular regionIEA-
 
InteractionsShown by Network
InteractorsAliases BOfficial full name BExperimentalSourcePubMed ID
C2CO2 | DKFZp779M0311complement component 2-HPRD,BioGRID10946278 
C4BPAC4BP | PRPcomplement component 4 binding protein, alpha-HPRD,BioGRID10383431 
CD46MCP | MGC26544 | MIC10 | TLX | TRA2.10CD46 molecule, complement regulatory protein-HPRD,BioGRID1717583 
CFBBF | BFD | CFAB | FB | FBI12 | GBG | H2-Bf | PBF2complement factor B-HPRD11341920 
CR1C3BR | CD35 | KNcomplement component (3b/4b) receptor 1 (Knops blood group)-HPRD,BioGRID10528211 
EEF1A1CCS-3 | CCS3 | EEF-1 | EEF1A | EF-Tu | EF1A | FLJ25721 | GRAF-1EF | HNGC:16303 | LENG7 | MGC102687 | MGC131894 | MGC16224 | PTI1 | eEF1A-1eukaryotic translation elongation factor 1 alpha 1-HPRD,BioGRID10851272 
 
Pathway annotation
Pathway namePathway size# SZGR genes in pathwayInfo
KEGG_COMPLEMENT_AND_COAGULATION_CASCADES 6949All SZGR genes in this pathway
KEGG_SYSTEMIC_LUPUS_ERYTHEMATOSUS 140100All SZGR genes in this pathway
BIOCARTA_CLASSIC_PATHWAY 1411All SZGR genes in this pathway
BIOCARTA_COMP_PATHWAY 1915All SZGR genes in this pathway
BIOCARTA_LECTIN_PATHWAY 1210All SZGR genes in this pathway
BENPORATH_CYCLING_GENES 648385All SZGR genes in this pathway
LEE_TARGETS_OF_PTCH1_AND_SUFU_UP 5337All SZGR genes in this pathway
ZHENG_GLIOBLASTOMA_PLASTICITY_UP 250168All SZGR genes in this pathway
VANTVEER_BREAST_CANCER_ESR1_UP 16799All SZGR genes in this pathway
COLINA_TARGETS_OF_4EBP1_AND_4EBP2 356214All SZGR genes in this pathway
LIU_VAV3_PROSTATE_CARCINOGENESIS_UP 8961All SZGR genes in this pathway
KARLSSON_TGFB1_TARGETS_DN 207139All SZGR genes in this pathway
GOBERT_OLIGODENDROCYTE_DIFFERENTIATION_DN 1080713All SZGR genes in this pathway


Copyright © Bioinformatics and Systems Medicine Laboratory All Rights Reserved since 2009.